Kyrieleis Plaques in Ocular Tuberculosis: A Case Report

• Autor(a) principal: Leuzinger-Dias, Mariana
• Data de Publicação: 2022
• Outros Autores: Lima-Fontes, Mário, Oliveira-Ferreira, Cláudia, Falcão-Reis, Fernando, Figueira, Luís
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: https://doi.org/10.48560/rspo.25706
• topic: Casos Clínicos

Kyrieleis plaques are a rare fundoscopic sign, in which multiple yellowish-white deposits are arranged in a beaded pattern along the branches of the central retinal artery. Their presence reflects severe intraocular inflammation, typically associated with infectious posterior uveitis. Here, we describe the case of a 58-year-old man who presented to our emergency department with a right red-eye, vision loss and floaters. The ophthalmological exam revealed unilateral panuveitis with the presence of Kyrieleis plaques. Laboratory evaluation was marked by a positive Mantoux skin test and a presumptive diagnosis of ocular tuberculosis was made. The patient was treated for active disease with a 4-drug anti-tuberculosis regimen, along with topical and oral corticosteroids, which allowed for the complete resolution of vitritis, gradual fading of the plaques and total vision recovery. Due to its rarity and strong association with infectious etiologies, the presence of Kyrieleis plaques in our patient ́s eye fundus was crucial to narrow the range of possible differential diagnoses. Accurate diagnosis subsequently led to prompt and adequate treatment, with great visual outcomes.