Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/64215 |
Resumo: | Featured Application: The loading of pharmaceuticals and cosmeceuticals into nanomaterials is discussed as new formulations for potential treatment of age-related skin problems. Topical administration of active ingredients formulated as nanopharmaceuticals and nanonutraceuticals is discussed.Abstract: Skin aging is described as dermatologic changes either naturally occurring over the course of years or as the result of the exposure to environmental factors (e.g., chemical products, pollution, infrared and ultraviolet radiations). The production of collagen and elastin, the main structural proteins responsible for skin strength and elasticity, is reduced during aging, while their role in skin rejuvenation can trigger a wrinkle reversing effect. Elasticity loss, wrinkles, dry skin, and thinning are some of the signs that can be associated with skin aging. To overcome skin aging, many strategies using natural and synthetic ingredients are being developed aiming to reduce the signs of aging and/or to treat age-related skin problems (e.g., spots, hyper- or hypopigmentation). Among the different approaches in tissue regeneration, the use of nanomaterials loaded with cosmeceuticals (e.g., phytochemicals, vitamins, hyaluronic acid, and growth factors) has become an interesting alternative. Based on their bioactivities and using different nanoformulations as efficient delivery systems, several cosmeceutical and pharmaceutical products are now available on the market aiming to mitigate the signs of aged skin. This manuscript discusses the state of the art of nanomaterials commonly used for topical administration of active ingredients formulated in nanopharmaceuticals and nanocosmeceuticals for skin anti-aging. |
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Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticalsskin agingnanomaterialsnanocosmeceuticalsnanopharmaceuticalsScience & TechnologyFeatured Application: The loading of pharmaceuticals and cosmeceuticals into nanomaterials is discussed as new formulations for potential treatment of age-related skin problems. Topical administration of active ingredients formulated as nanopharmaceuticals and nanonutraceuticals is discussed.Abstract: Skin aging is described as dermatologic changes either naturally occurring over the course of years or as the result of the exposure to environmental factors (e.g., chemical products, pollution, infrared and ultraviolet radiations). The production of collagen and elastin, the main structural proteins responsible for skin strength and elasticity, is reduced during aging, while their role in skin rejuvenation can trigger a wrinkle reversing effect. Elasticity loss, wrinkles, dry skin, and thinning are some of the signs that can be associated with skin aging. To overcome skin aging, many strategies using natural and synthetic ingredients are being developed aiming to reduce the signs of aging and/or to treat age-related skin problems (e.g., spots, hyper- or hypopigmentation). Among the different approaches in tissue regeneration, the use of nanomaterials loaded with cosmeceuticals (e.g., phytochemicals, vitamins, hyaluronic acid, and growth factors) has become an interesting alternative. Based on their bioactivities and using different nanoformulations as efficient delivery systems, several cosmeceutical and pharmaceutical products are now available on the market aiming to mitigate the signs of aged skin. This manuscript discusses the state of the art of nanomaterials commonly used for topical administration of active ingredients formulated in nanopharmaceuticals and nanocosmeceuticals for skin anti-aging.The authors acknowledge the financial support received from Portuguese Science and Technology Foundation (FCT/MCT) and from European Funds (PRODER/COMPETE) for the projects M-ERANET/0004/2015-PAIRED and UIDB/04469/2020 (strategic fund) co-financed by FEDER, under the Partnership Agreement PT2020. The FCT grant to CMG (SFRH/BD/145855/2019) and project PEst-OE/UID/AGR/04033/2019 (CITAB strategic fund) are also acknowledged. The authors acknowledge the support of the research project: Nutraceutica come supporto nutrizionale nel paziente oncologico, CUP: B83D18000140007.info:eu-repo/semantics/publishedVersionMDPIUniversidade do MinhoSouto, Eliana B.Fernandes, Ana RitaMartins-Gomes, CarlosCoutinho, Tiago E.Durazzo, AlessandraLucarini, MassimoSouto, Selma B.Silva, Amélia M.Santini, Antonello20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/64215engSouto, Eliana; Fernandes, Ana Rita; Martins-Gomes, Carlos; Coutinho, Tiago E.; Durazzo, Alessandra; Lucarini, Massimo; Souto, Selma B.; Silva, Amélia M.; Santini, Antonello, Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals. Applied Sciences-Basel, 10(5), 1594, 20202076-341710.3390/app10051594http://www.mdpi.com/journal/applsciinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:34:05Zoai:repositorium.sdum.uminho.pt:1822/64215Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:29:42.481235Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals |
title |
Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals |
spellingShingle |
Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals Souto, Eliana B. skin aging nanomaterials nanocosmeceuticals nanopharmaceuticals Science & Technology |
title_short |
Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals |
title_full |
Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals |
title_fullStr |
Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals |
title_full_unstemmed |
Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals |
title_sort |
Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals |
author |
Souto, Eliana B. |
author_facet |
Souto, Eliana B. Fernandes, Ana Rita Martins-Gomes, Carlos Coutinho, Tiago E. Durazzo, Alessandra Lucarini, Massimo Souto, Selma B. Silva, Amélia M. Santini, Antonello |
author_role |
author |
author2 |
Fernandes, Ana Rita Martins-Gomes, Carlos Coutinho, Tiago E. Durazzo, Alessandra Lucarini, Massimo Souto, Selma B. Silva, Amélia M. Santini, Antonello |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Souto, Eliana B. Fernandes, Ana Rita Martins-Gomes, Carlos Coutinho, Tiago E. Durazzo, Alessandra Lucarini, Massimo Souto, Selma B. Silva, Amélia M. Santini, Antonello |
dc.subject.por.fl_str_mv |
skin aging nanomaterials nanocosmeceuticals nanopharmaceuticals Science & Technology |
topic |
skin aging nanomaterials nanocosmeceuticals nanopharmaceuticals Science & Technology |
description |
Featured Application: The loading of pharmaceuticals and cosmeceuticals into nanomaterials is discussed as new formulations for potential treatment of age-related skin problems. Topical administration of active ingredients formulated as nanopharmaceuticals and nanonutraceuticals is discussed.Abstract: Skin aging is described as dermatologic changes either naturally occurring over the course of years or as the result of the exposure to environmental factors (e.g., chemical products, pollution, infrared and ultraviolet radiations). The production of collagen and elastin, the main structural proteins responsible for skin strength and elasticity, is reduced during aging, while their role in skin rejuvenation can trigger a wrinkle reversing effect. Elasticity loss, wrinkles, dry skin, and thinning are some of the signs that can be associated with skin aging. To overcome skin aging, many strategies using natural and synthetic ingredients are being developed aiming to reduce the signs of aging and/or to treat age-related skin problems (e.g., spots, hyper- or hypopigmentation). Among the different approaches in tissue regeneration, the use of nanomaterials loaded with cosmeceuticals (e.g., phytochemicals, vitamins, hyaluronic acid, and growth factors) has become an interesting alternative. Based on their bioactivities and using different nanoformulations as efficient delivery systems, several cosmeceutical and pharmaceutical products are now available on the market aiming to mitigate the signs of aged skin. This manuscript discusses the state of the art of nanomaterials commonly used for topical administration of active ingredients formulated in nanopharmaceuticals and nanocosmeceuticals for skin anti-aging. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020 2020-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/64215 |
url |
http://hdl.handle.net/1822/64215 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Souto, Eliana; Fernandes, Ana Rita; Martins-Gomes, Carlos; Coutinho, Tiago E.; Durazzo, Alessandra; Lucarini, Massimo; Souto, Selma B.; Silva, Amélia M.; Santini, Antonello, Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals. Applied Sciences-Basel, 10(5), 1594, 2020 2076-3417 10.3390/app10051594 http://www.mdpi.com/journal/applsci |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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