Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals

Detalhes bibliográficos
Autor(a) principal: Souto, Eliana B.
Data de Publicação: 2020
Outros Autores: Fernandes, Ana Rita, Martins-Gomes, Carlos, Coutinho, Tiago E., Durazzo, Alessandra, Lucarini, Massimo, Souto, Selma B., Silva, Amélia M., Santini, Antonello
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/64215
Resumo: Featured Application: The loading of pharmaceuticals and cosmeceuticals into nanomaterials is discussed as new formulations for potential treatment of age-related skin problems. Topical administration of active ingredients formulated as nanopharmaceuticals and nanonutraceuticals is discussed.Abstract: Skin aging is described as dermatologic changes either naturally occurring over the course of years or as the result of the exposure to environmental factors (e.g., chemical products, pollution, infrared and ultraviolet radiations). The production of collagen and elastin, the main structural proteins responsible for skin strength and elasticity, is reduced during aging, while their role in skin rejuvenation can trigger a wrinkle reversing effect. Elasticity loss, wrinkles, dry skin, and thinning are some of the signs that can be associated with skin aging. To overcome skin aging, many strategies using natural and synthetic ingredients are being developed aiming to reduce the signs of aging and/or to treat age-related skin problems (e.g., spots, hyper- or hypopigmentation). Among the different approaches in tissue regeneration, the use of nanomaterials loaded with cosmeceuticals (e.g., phytochemicals, vitamins, hyaluronic acid, and growth factors) has become an interesting alternative. Based on their bioactivities and using different nanoformulations as efficient delivery systems, several cosmeceutical and pharmaceutical products are now available on the market aiming to mitigate the signs of aged skin. This manuscript discusses the state of the art of nanomaterials commonly used for topical administration of active ingredients formulated in nanopharmaceuticals and nanocosmeceuticals for skin anti-aging.
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spelling Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticalsskin agingnanomaterialsnanocosmeceuticalsnanopharmaceuticalsScience & TechnologyFeatured Application: The loading of pharmaceuticals and cosmeceuticals into nanomaterials is discussed as new formulations for potential treatment of age-related skin problems. Topical administration of active ingredients formulated as nanopharmaceuticals and nanonutraceuticals is discussed.Abstract: Skin aging is described as dermatologic changes either naturally occurring over the course of years or as the result of the exposure to environmental factors (e.g., chemical products, pollution, infrared and ultraviolet radiations). The production of collagen and elastin, the main structural proteins responsible for skin strength and elasticity, is reduced during aging, while their role in skin rejuvenation can trigger a wrinkle reversing effect. Elasticity loss, wrinkles, dry skin, and thinning are some of the signs that can be associated with skin aging. To overcome skin aging, many strategies using natural and synthetic ingredients are being developed aiming to reduce the signs of aging and/or to treat age-related skin problems (e.g., spots, hyper- or hypopigmentation). Among the different approaches in tissue regeneration, the use of nanomaterials loaded with cosmeceuticals (e.g., phytochemicals, vitamins, hyaluronic acid, and growth factors) has become an interesting alternative. Based on their bioactivities and using different nanoformulations as efficient delivery systems, several cosmeceutical and pharmaceutical products are now available on the market aiming to mitigate the signs of aged skin. This manuscript discusses the state of the art of nanomaterials commonly used for topical administration of active ingredients formulated in nanopharmaceuticals and nanocosmeceuticals for skin anti-aging.The authors acknowledge the financial support received from Portuguese Science and Technology Foundation (FCT/MCT) and from European Funds (PRODER/COMPETE) for the projects M-ERANET/0004/2015-PAIRED and UIDB/04469/2020 (strategic fund) co-financed by FEDER, under the Partnership Agreement PT2020. The FCT grant to CMG (SFRH/BD/145855/2019) and project PEst-OE/UID/AGR/04033/2019 (CITAB strategic fund) are also acknowledged. The authors acknowledge the support of the research project: Nutraceutica come supporto nutrizionale nel paziente oncologico, CUP: B83D18000140007.info:eu-repo/semantics/publishedVersionMDPIUniversidade do MinhoSouto, Eliana B.Fernandes, Ana RitaMartins-Gomes, CarlosCoutinho, Tiago E.Durazzo, AlessandraLucarini, MassimoSouto, Selma B.Silva, Amélia M.Santini, Antonello20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/64215engSouto, Eliana; Fernandes, Ana Rita; Martins-Gomes, Carlos; Coutinho, Tiago E.; Durazzo, Alessandra; Lucarini, Massimo; Souto, Selma B.; Silva, Amélia M.; Santini, Antonello, Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals. Applied Sciences-Basel, 10(5), 1594, 20202076-341710.3390/app10051594http://www.mdpi.com/journal/applsciinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:34:05Zoai:repositorium.sdum.uminho.pt:1822/64215Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:29:42.481235Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals
title Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals
spellingShingle Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals
Souto, Eliana B.
skin aging
nanomaterials
nanocosmeceuticals
nanopharmaceuticals
Science & Technology
title_short Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals
title_full Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals
title_fullStr Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals
title_full_unstemmed Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals
title_sort Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals
author Souto, Eliana B.
author_facet Souto, Eliana B.
Fernandes, Ana Rita
Martins-Gomes, Carlos
Coutinho, Tiago E.
Durazzo, Alessandra
Lucarini, Massimo
Souto, Selma B.
Silva, Amélia M.
Santini, Antonello
author_role author
author2 Fernandes, Ana Rita
Martins-Gomes, Carlos
Coutinho, Tiago E.
Durazzo, Alessandra
Lucarini, Massimo
Souto, Selma B.
Silva, Amélia M.
Santini, Antonello
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Souto, Eliana B.
Fernandes, Ana Rita
Martins-Gomes, Carlos
Coutinho, Tiago E.
Durazzo, Alessandra
Lucarini, Massimo
Souto, Selma B.
Silva, Amélia M.
Santini, Antonello
dc.subject.por.fl_str_mv skin aging
nanomaterials
nanocosmeceuticals
nanopharmaceuticals
Science & Technology
topic skin aging
nanomaterials
nanocosmeceuticals
nanopharmaceuticals
Science & Technology
description Featured Application: The loading of pharmaceuticals and cosmeceuticals into nanomaterials is discussed as new formulations for potential treatment of age-related skin problems. Topical administration of active ingredients formulated as nanopharmaceuticals and nanonutraceuticals is discussed.Abstract: Skin aging is described as dermatologic changes either naturally occurring over the course of years or as the result of the exposure to environmental factors (e.g., chemical products, pollution, infrared and ultraviolet radiations). The production of collagen and elastin, the main structural proteins responsible for skin strength and elasticity, is reduced during aging, while their role in skin rejuvenation can trigger a wrinkle reversing effect. Elasticity loss, wrinkles, dry skin, and thinning are some of the signs that can be associated with skin aging. To overcome skin aging, many strategies using natural and synthetic ingredients are being developed aiming to reduce the signs of aging and/or to treat age-related skin problems (e.g., spots, hyper- or hypopigmentation). Among the different approaches in tissue regeneration, the use of nanomaterials loaded with cosmeceuticals (e.g., phytochemicals, vitamins, hyaluronic acid, and growth factors) has become an interesting alternative. Based on their bioactivities and using different nanoformulations as efficient delivery systems, several cosmeceutical and pharmaceutical products are now available on the market aiming to mitigate the signs of aged skin. This manuscript discusses the state of the art of nanomaterials commonly used for topical administration of active ingredients formulated in nanopharmaceuticals and nanocosmeceuticals for skin anti-aging.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/64215
url http://hdl.handle.net/1822/64215
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Souto, Eliana; Fernandes, Ana Rita; Martins-Gomes, Carlos; Coutinho, Tiago E.; Durazzo, Alessandra; Lucarini, Massimo; Souto, Selma B.; Silva, Amélia M.; Santini, Antonello, Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals. Applied Sciences-Basel, 10(5), 1594, 2020
2076-3417
10.3390/app10051594
http://www.mdpi.com/journal/applsci
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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