Hereditary Thrombophilia and Pregnancy: Thrombotic Risk and Pregnancy Outcome

Detalhes bibliográficos
Autor(a) principal: Fonseca, Ana Glória
Data de Publicação: 2013
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1362
Resumo: Thromboembolic disease and obstetric complications related to ischemia of the placenta are currently the major causes of maternalmortality and morbidity. Thrombophilia been implicated in their aetiology and the magnitude of the risk depends on the type of thrombophilia.As the evidence is still unclear and controversial, questions about the clinical management of pregnant women with thrombophiliaare a daily issue. We aim to review, bearing in mind the consensus and controversies, the impact of inherited thrombophilia in the risk ofthrombosis related to pregnancy and of obstetric complications. Moreover, the diagnostic, preventive and therapeutic approach duringpregnancy and puerperium, including the role of antithrombotic pharmacopoeia available, will be discussed.
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spelling Hereditary Thrombophilia and Pregnancy: Thrombotic Risk and Pregnancy OutcomeAs Trombofilias Hereditárias na Grávida: do Risco Trombótico ao Sucesso da GravidezThromboembolic disease and obstetric complications related to ischemia of the placenta are currently the major causes of maternalmortality and morbidity. Thrombophilia been implicated in their aetiology and the magnitude of the risk depends on the type of thrombophilia.As the evidence is still unclear and controversial, questions about the clinical management of pregnant women with thrombophiliaare a daily issue. We aim to review, bearing in mind the consensus and controversies, the impact of inherited thrombophilia in the risk ofthrombosis related to pregnancy and of obstetric complications. Moreover, the diagnostic, preventive and therapeutic approach duringpregnancy and puerperium, including the role of antithrombotic pharmacopoeia available, will be discussed.A doença tromboembólica e as complicações obstétricas relacionadas com isquémia da placenta são actualmente as principais causasde mortalidade e morbilidade maternas. As trombofilias foram implicadas na sua etiologia, variando a magnitude do risco emfunção do tipo de trombofilia. Sendo a evidência ainda pouco clara e controversa, as questões sobre a abordagem clínica da grávidacom trombofilia colocam-se diariamente. Neste sentido, pretende-se rever, tendo em conta os consensos e controvérsias, o impactodas trombofilias hereditárias no risco trombótico e no sucesso da gravidez, desde a perspectiva diagnóstica à abordagem preventivae terapêutica, incluindo o papel da farmacopeia antitrombótica disponível.Ordem dos Médicos2013-01-28info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/x-pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1362oai:ojs.www.actamedicaportuguesa.com:article/1362Acta Médica Portuguesa; Vol. 25 No. 6 (2012): November-December; 433-441Acta Médica Portuguesa; Vol. 25 N.º 6 (2012): Novembro-Dezembro; 433-4411646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1362https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1362/954Fonseca, Ana Glóriainfo:eu-repo/semantics/openAccess2022-12-20T10:57:47Zoai:ojs.www.actamedicaportuguesa.com:article/1362Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:17:05.497255Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Hereditary Thrombophilia and Pregnancy: Thrombotic Risk and Pregnancy Outcome
As Trombofilias Hereditárias na Grávida: do Risco Trombótico ao Sucesso da Gravidez
title Hereditary Thrombophilia and Pregnancy: Thrombotic Risk and Pregnancy Outcome
spellingShingle Hereditary Thrombophilia and Pregnancy: Thrombotic Risk and Pregnancy Outcome
Fonseca, Ana Glória
title_short Hereditary Thrombophilia and Pregnancy: Thrombotic Risk and Pregnancy Outcome
title_full Hereditary Thrombophilia and Pregnancy: Thrombotic Risk and Pregnancy Outcome
title_fullStr Hereditary Thrombophilia and Pregnancy: Thrombotic Risk and Pregnancy Outcome
title_full_unstemmed Hereditary Thrombophilia and Pregnancy: Thrombotic Risk and Pregnancy Outcome
title_sort Hereditary Thrombophilia and Pregnancy: Thrombotic Risk and Pregnancy Outcome
author Fonseca, Ana Glória
author_facet Fonseca, Ana Glória
author_role author
dc.contributor.author.fl_str_mv Fonseca, Ana Glória
description Thromboembolic disease and obstetric complications related to ischemia of the placenta are currently the major causes of maternalmortality and morbidity. Thrombophilia been implicated in their aetiology and the magnitude of the risk depends on the type of thrombophilia.As the evidence is still unclear and controversial, questions about the clinical management of pregnant women with thrombophiliaare a daily issue. We aim to review, bearing in mind the consensus and controversies, the impact of inherited thrombophilia in the risk ofthrombosis related to pregnancy and of obstetric complications. Moreover, the diagnostic, preventive and therapeutic approach duringpregnancy and puerperium, including the role of antithrombotic pharmacopoeia available, will be discussed.
publishDate 2013
dc.date.none.fl_str_mv 2013-01-28
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1362
oai:ojs.www.actamedicaportuguesa.com:article/1362
url https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1362
identifier_str_mv oai:ojs.www.actamedicaportuguesa.com:article/1362
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1362
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1362/954
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/x-pdf
dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 25 No. 6 (2012): November-December; 433-441
Acta Médica Portuguesa; Vol. 25 N.º 6 (2012): Novembro-Dezembro; 433-441
1646-0758
0870-399X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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