Marine sponges : a new source of bioactive ceramics for tissue engineering and regenerative medicine applications

Detalhes bibliográficos
Autor(a) principal: Barros, Alexandre A.
Data de Publicação: 2013
Outros Autores: Aroso, Ivo Manuel Ascensão, Silva, Tiago H., Mano, J. F., Duarte, Ana Rita C., Reis, R. L.
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/36584
Resumo: Publicado em : "Journal of Tissue Engineering and Regenerative Medicine", vol, 7, supp. 1 (2013)
id RCAP_c641856a0894dca83fe86a6a0e8d0d1e
oai_identifier_str oai:repositorium.sdum.uminho.pt:1822/36584
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Marine sponges : a new source of bioactive ceramics for tissue engineering and regenerative medicine applicationsBioactiveMarine spongesTissue engineering and regenerative medicinePublicado em : "Journal of Tissue Engineering and Regenerative Medicine", vol, 7, supp. 1 (2013)Marine organisms are exceptionally rich in natural products and present huge prospective for biomedical applications. In this work we have studied the potential of bioceramics from different sponge species, namely Petrosia ficidormis, Agelas oroides and Chondrosia reniformis, for novel biomedical applications. Studies reported in the literature have already demonstrated the potential of carbonate corals as a source of bioceramics. However, similar studies directed towards the valorization of marine sponge skeletons are still missing. The bioceramics, exempt of organic components, were obtained after calcination of the sponges at 750°C for 6 hours in a furnace. The powder was recovered and Scanning electron microscopy (SEM) was used to observe the morphology and gain insight of the elements spatial arrangement. Spectroscopic elemental analysis (EDS) was used to determine the chemical composition and has shown that Petrosia ficidormis skeleton is constituted mainly by silicate, while Chondrosia reniformis spicules are mostly calcium carbonates. On the other hand, the ceramics obtained from Agelas oroides present a combination of silicate and calcium salts. In vitro bioactivity of the bioceramics was evaluated in simulated body fluid (SBF), after 3, 7 and 14 days of incubation. Observation of the bioceramics by SEM, coupled with EDS, has shown that it is possible to induce the precipitation of calcium-phosphate crystals, consistent with similar to hydroxyapatite (HA) coating. The determination of Ca/P ratio, together with the infrared spectrum by Fourier transform infrared spectroscopy (FTIR) and x-Ray diffraction (XRD) pattern, has confirmed the deposition of HA. Cytotoxicity of developed bioceramics materials was also assessed, comparing their behaviour with synthetized bioactive glass as reference. Results obtained thus far have shown the potential of bioceramics from marine sponges for its use in biomedical applications, namely in tissue regeneration approachesJohn Wiley and SonsUniversidade do MinhoBarros, Alexandre A.Aroso, Ivo Manuel AscensãoSilva, Tiago H.Mano, J. F.Duarte, Ana Rita C.Reis, R. L.2013-102013-10-01T00:00:00Zconference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/1822/36584engBarros A. A., Aroso I. M., Silva T. H., Mano J. F., Duarte A. R. C., Reis R. L. Marine sponges – a new source of bioactive ceramics for tissue engineering and regenerative medicine applications, Journal of Tissue Engineering and Regenerative Medicine, Vol. 7, Issue 10, pp. 46, doi:10.1002/term.1822, 2013http://onlinelibrary.wiley.com/doi/10.1002/term.1822/pdfinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-05-11T06:47:10Zoai:repositorium.sdum.uminho.pt:1822/36584Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-05-11T06:47:10Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Marine sponges : a new source of bioactive ceramics for tissue engineering and regenerative medicine applications
title Marine sponges : a new source of bioactive ceramics for tissue engineering and regenerative medicine applications
spellingShingle Marine sponges : a new source of bioactive ceramics for tissue engineering and regenerative medicine applications
Barros, Alexandre A.
Bioactive
Marine sponges
Tissue engineering and regenerative medicine
title_short Marine sponges : a new source of bioactive ceramics for tissue engineering and regenerative medicine applications
title_full Marine sponges : a new source of bioactive ceramics for tissue engineering and regenerative medicine applications
title_fullStr Marine sponges : a new source of bioactive ceramics for tissue engineering and regenerative medicine applications
title_full_unstemmed Marine sponges : a new source of bioactive ceramics for tissue engineering and regenerative medicine applications
title_sort Marine sponges : a new source of bioactive ceramics for tissue engineering and regenerative medicine applications
author Barros, Alexandre A.
author_facet Barros, Alexandre A.
Aroso, Ivo Manuel Ascensão
Silva, Tiago H.
Mano, J. F.
Duarte, Ana Rita C.
Reis, R. L.
author_role author
author2 Aroso, Ivo Manuel Ascensão
Silva, Tiago H.
Mano, J. F.
Duarte, Ana Rita C.
Reis, R. L.
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Barros, Alexandre A.
Aroso, Ivo Manuel Ascensão
Silva, Tiago H.
Mano, J. F.
Duarte, Ana Rita C.
Reis, R. L.
dc.subject.por.fl_str_mv Bioactive
Marine sponges
Tissue engineering and regenerative medicine
topic Bioactive
Marine sponges
Tissue engineering and regenerative medicine
description Publicado em : "Journal of Tissue Engineering and Regenerative Medicine", vol, 7, supp. 1 (2013)
publishDate 2013
dc.date.none.fl_str_mv 2013-10
2013-10-01T00:00:00Z
dc.type.driver.fl_str_mv conference object
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/36584
url http://hdl.handle.net/1822/36584
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Barros A. A., Aroso I. M., Silva T. H., Mano J. F., Duarte A. R. C., Reis R. L. Marine sponges – a new source of bioactive ceramics for tissue engineering and regenerative medicine applications, Journal of Tissue Engineering and Regenerative Medicine, Vol. 7, Issue 10, pp. 46, doi:10.1002/term.1822, 2013
http://onlinelibrary.wiley.com/doi/10.1002/term.1822/pdf
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv John Wiley and Sons
publisher.none.fl_str_mv John Wiley and Sons
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv mluisa.alvim@gmail.com
_version_ 1817545092724948992

Registros relacionados