IMMUNE RECONSTITUTION INFLAMMATORY SYNDROME: A POTENTIAL PITFALL IN THE MANAGEMENT OF KAPOSI’S SARCOMA IN HIV POSITIVE PATIENTS? – A CASE REPORT

• Autor(a) principal: Ladeira de Oliveira, Felipe
• Data de Publicação: 2014
• Outros Autores: Sírio, Deborah Maria Brito, Cerutti, Gisele, de Natividade, Natalia Barreiros, de Menezes, Vinicius Martins, Miranda, Alice, Azulay-Abulafia, Luna, Nery, José Augusto da Costa
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: https://doi.org/10.29021/spdv.71.2.177
• topic: Antiretroviral therapy; highly active; HIV infections; Sarcoma; Kaposi; Infecção por VIH; Sarcoma de Kaposi; HAART

The variety of immune reconstitution inflammatory syndrome’s (IRIS) clinical presentations makes this syndrome a challenge, in that it is difficult to manage opportunistic infections and other serious clinical conditions related to the manifestation of this syndrome. The relevance of immune reconstitution inflammatory syndrome – associated with Kaposi sarcoma (IRIS-KS) after initiation of highly active antiretroviral therapy (HAART) is noteworthy, mainly in coun tries that still have high levels of transmission of sexually transmitted diseases and HIV. Clinicians and dermatologists should be aware to identify signs and symptoms of this neoplasm progression and to differentiate them from KS related IRIS according to the recent classification criteria of this disease and antiretroviral therapy should not be discontinued in the most cases.