Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15031 |
Resumo: | Introduction: Since the publication of endovascular treatment trials and European Stroke Guidelines, Portugal has re-organized stroke healthcare. The nine centers performing endovascular treatment are not equally distributed within the country, which may lead to differential access to endovascular treatment. Our main aim was to perform a descriptive analysis of the main treatment metrics regarding endovascular treatment in mainland Portugal and its administrative districts.Material and Methods: A retrospective national multicentric cohort study was conducted, including all ischemic stroke patients treated with endovascular treatment in mainland Portugal over two years (July 2015 to June 2017). All endovascular treatment centers contributed to an anonymized database. Demographic, stroke-related and procedure-related variables were collected. Crude endovascular treatment rates were calculated per 100 000 inhabitants for mainland Portugal, and each district and endovascular treatment standardized ratios (indirect age-sex standardization) were also calculated. Patient time metrics were computed as the median time between stroke onset, first-door, and puncture.Results: A total of 1625 endovascular treatment procedures were registered. The endovascular treatment rate was 8.27/100 000 inhabitants/year. We found regional heterogeneity in endovascular treatment rates (1.58 to 16.53/100 000/year), with higher rates in districts closer to endovascular treatment centers. When analyzed by district, the median time from stroke onset to puncture ranged from 212 to 432 minutes, reflecting regional heterogeneity.Conclusion: The overall national rate of EVT in the first two years after the organization of EVT-capable centers is one of the highest among European countries, however, significant regional disparities were documented. Moreover, stroke-onset-to-first-door times and in-hospital procedural times in the EVT centers were comparable to those reported in the randomized controlled trials performed in high-volume tertiary hospitals. |
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Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in PortugalAcesso a Tratamento Endovascular para Acidente Vascular Cerebral Isquémico em PortugalEndovascular ProceduresIschemic StrokeMechanical ThrombolysisPortugalThrombectomyAcidente Vascular Cerebral IsquémicoPortugalProcedimentos EndovascularesTrombólise MecânicaTrombectomiaIntroduction: Since the publication of endovascular treatment trials and European Stroke Guidelines, Portugal has re-organized stroke healthcare. The nine centers performing endovascular treatment are not equally distributed within the country, which may lead to differential access to endovascular treatment. Our main aim was to perform a descriptive analysis of the main treatment metrics regarding endovascular treatment in mainland Portugal and its administrative districts.Material and Methods: A retrospective national multicentric cohort study was conducted, including all ischemic stroke patients treated with endovascular treatment in mainland Portugal over two years (July 2015 to June 2017). All endovascular treatment centers contributed to an anonymized database. Demographic, stroke-related and procedure-related variables were collected. Crude endovascular treatment rates were calculated per 100 000 inhabitants for mainland Portugal, and each district and endovascular treatment standardized ratios (indirect age-sex standardization) were also calculated. Patient time metrics were computed as the median time between stroke onset, first-door, and puncture.Results: A total of 1625 endovascular treatment procedures were registered. The endovascular treatment rate was 8.27/100 000 inhabitants/year. We found regional heterogeneity in endovascular treatment rates (1.58 to 16.53/100 000/year), with higher rates in districts closer to endovascular treatment centers. When analyzed by district, the median time from stroke onset to puncture ranged from 212 to 432 minutes, reflecting regional heterogeneity.Conclusion: The overall national rate of EVT in the first two years after the organization of EVT-capable centers is one of the highest among European countries, however, significant regional disparities were documented. Moreover, stroke-onset-to-first-door times and in-hospital procedural times in the EVT centers were comparable to those reported in the randomized controlled trials performed in high-volume tertiary hospitals.Introdução: A aprovação do tratamento endovascular para o acidente vascular cerebral isquémico obrigou à reorganização dos cuidados de saúde em Portugal. Os nove centros que realizam tratamento endovascular não estão distribuídos equitativamente pelo território, o que poderá causar acesso diferencial a tratamento. O principal objetivo deste estudo é realizar uma análise descritiva da frequência e métricas temporais do tratamento endovascular em Portugal continental e seus distritos.Material e Métodos: Estudo de coorte nacional multicêntrico, incluindo todos os doentes com acidente vascular cerebral isquémico submetidos a tratamento endovascular em Portugal continental durante um período de dois anos (julho 2015 a junho 2017). Foram colhidos dados demográficos, relacionados com o acidente vascular cerebral e variáveis do procedimento. Taxas de tratamento endovascular brutas e ajustadas (ajuste indireto a idade e sexo) foram calculadas por 100 000 habitantes/ano para Portugal continental e cada distrito. Métricas de procedimento como tempo entre instalação, primeira porta e punção foram também analisadas.Resultados: Foram registados 1625 tratamentos endovasculares, indicando uma taxa bruta nacional de tratamento endovascular de 8,27/100 000 habitantes/ano. As taxas de tratamento endovascular entre distritos variaram entre 1,58 e 16,53/100 000/ano, com taxas mais elevadas nos distritos próximos a hospitais com tratamento endovascular. O tempo entre sintomas e punção femural entre distritos variou entre 212 e 432 minutos.Conclusão: Portugal continental apresenta uma taxa nacional de tratamento endovascular elevada, apresentando, contudo, assimetrias regionais no acesso. As métricas temporais foram comparáveis com as observadas nos ensaios clínicos piloto.Ordem dos Médicos2022-02-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15031Acta Médica Portuguesa; Vol. 35 No. 2 (2022): February; 127-134Acta Médica Portuguesa; Vol. 35 N.º 2 (2022): Fevereiro; 127-1341646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15031https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15031/6436https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15031/6437https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15031/6438Direitos de Autor (c) 2021 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessDias, Mariana Carvalhodos Reis, Ricardo SoaresSantos, João VascoNunes, Ana PaivaFerreira, PatriciaMaia, BrunoFragata, IsabelReis, JoaoLopes, Joana RamosCruz, LuisSanto, GustavoMachado, EgidioGabriel, DenisFelgueiras, RuiDória, Hugo MotaCarneiro, AngeloCorreia, ManuelVeloso, Luis MiguelBarros, PedroGregorio, TiagoCarvalho, AndreiaRibeiro, ManuelTeotonio, PedroNeto, Liae Melo, Teresa PinhoCanhao, PatriciaFilipe, João PedroMoreira, GoretiAzevedo, ElsaSilva, Maria LuisCosta, Elisa CamposOliveira, GuilhermePereira, LilianaNeves, LigiaRodrigues, MiguelMarto, João PedroCalado, SofiaGrenho, FatimaBranco, GabrielBaptista, TiagoRocha, JaimeFerreira, CarlaPinho, JoaoAmorim, José ManuelAraujo, José ManuelNeiva, Rui ManuelViana, JoãoLobo, MarianaFreitas, AlbertoCruz, Vitor TedimSargento-Freitas, JoãoLopes, José Castro2023-01-22T03:00:45Zoai:ojs.www.actamedicaportuguesa.com:article/15031Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:20:33.881823Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal Acesso a Tratamento Endovascular para Acidente Vascular Cerebral Isquémico em Portugal |
title |
Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal |
spellingShingle |
Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal Dias, Mariana Carvalho Endovascular Procedures Ischemic Stroke Mechanical Thrombolysis Portugal Thrombectomy Acidente Vascular Cerebral Isquémico Portugal Procedimentos Endovasculares Trombólise Mecânica Trombectomia |
title_short |
Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal |
title_full |
Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal |
title_fullStr |
Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal |
title_full_unstemmed |
Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal |
title_sort |
Nationwide Access to Endovascular Treatment for Acute Ischemic Stroke in Portugal |
author |
Dias, Mariana Carvalho |
author_facet |
Dias, Mariana Carvalho dos Reis, Ricardo Soares Santos, João Vasco Nunes, Ana Paiva Ferreira, Patricia Maia, Bruno Fragata, Isabel Reis, Joao Lopes, Joana Ramos Cruz, Luis Santo, Gustavo Machado, Egidio Gabriel, Denis Felgueiras, Rui Dória, Hugo Mota Carneiro, Angelo Correia, Manuel Veloso, Luis Miguel Barros, Pedro Gregorio, Tiago Carvalho, Andreia Ribeiro, Manuel Teotonio, Pedro Neto, Lia e Melo, Teresa Pinho Canhao, Patricia Filipe, João Pedro Moreira, Goreti Azevedo, Elsa Silva, Maria Luis Costa, Elisa Campos Oliveira, Guilherme Pereira, Liliana Neves, Ligia Rodrigues, Miguel Marto, João Pedro Calado, Sofia Grenho, Fatima Branco, Gabriel Baptista, Tiago Rocha, Jaime Ferreira, Carla Pinho, Joao Amorim, José Manuel Araujo, José Manuel Neiva, Rui Manuel Viana, João Lobo, Mariana Freitas, Alberto Cruz, Vitor Tedim Sargento-Freitas, João Lopes, José Castro |
author_role |
author |
author2 |
dos Reis, Ricardo Soares Santos, João Vasco Nunes, Ana Paiva Ferreira, Patricia Maia, Bruno Fragata, Isabel Reis, Joao Lopes, Joana Ramos Cruz, Luis Santo, Gustavo Machado, Egidio Gabriel, Denis Felgueiras, Rui Dória, Hugo Mota Carneiro, Angelo Correia, Manuel Veloso, Luis Miguel Barros, Pedro Gregorio, Tiago Carvalho, Andreia Ribeiro, Manuel Teotonio, Pedro Neto, Lia e Melo, Teresa Pinho Canhao, Patricia Filipe, João Pedro Moreira, Goreti Azevedo, Elsa Silva, Maria Luis Costa, Elisa Campos Oliveira, Guilherme Pereira, Liliana Neves, Ligia Rodrigues, Miguel Marto, João Pedro Calado, Sofia Grenho, Fatima Branco, Gabriel Baptista, Tiago Rocha, Jaime Ferreira, Carla Pinho, Joao Amorim, José Manuel Araujo, José Manuel Neiva, Rui Manuel Viana, João Lobo, Mariana Freitas, Alberto Cruz, Vitor Tedim Sargento-Freitas, João Lopes, José Castro |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Dias, Mariana Carvalho dos Reis, Ricardo Soares Santos, João Vasco Nunes, Ana Paiva Ferreira, Patricia Maia, Bruno Fragata, Isabel Reis, Joao Lopes, Joana Ramos Cruz, Luis Santo, Gustavo Machado, Egidio Gabriel, Denis Felgueiras, Rui Dória, Hugo Mota Carneiro, Angelo Correia, Manuel Veloso, Luis Miguel Barros, Pedro Gregorio, Tiago Carvalho, Andreia Ribeiro, Manuel Teotonio, Pedro Neto, Lia e Melo, Teresa Pinho Canhao, Patricia Filipe, João Pedro Moreira, Goreti Azevedo, Elsa Silva, Maria Luis Costa, Elisa Campos Oliveira, Guilherme Pereira, Liliana Neves, Ligia Rodrigues, Miguel Marto, João Pedro Calado, Sofia Grenho, Fatima Branco, Gabriel Baptista, Tiago Rocha, Jaime Ferreira, Carla Pinho, Joao Amorim, José Manuel Araujo, José Manuel Neiva, Rui Manuel Viana, João Lobo, Mariana Freitas, Alberto Cruz, Vitor Tedim Sargento-Freitas, João Lopes, José Castro |
dc.subject.por.fl_str_mv |
Endovascular Procedures Ischemic Stroke Mechanical Thrombolysis Portugal Thrombectomy Acidente Vascular Cerebral Isquémico Portugal Procedimentos Endovasculares Trombólise Mecânica Trombectomia |
topic |
Endovascular Procedures Ischemic Stroke Mechanical Thrombolysis Portugal Thrombectomy Acidente Vascular Cerebral Isquémico Portugal Procedimentos Endovasculares Trombólise Mecânica Trombectomia |
description |
Introduction: Since the publication of endovascular treatment trials and European Stroke Guidelines, Portugal has re-organized stroke healthcare. The nine centers performing endovascular treatment are not equally distributed within the country, which may lead to differential access to endovascular treatment. Our main aim was to perform a descriptive analysis of the main treatment metrics regarding endovascular treatment in mainland Portugal and its administrative districts.Material and Methods: A retrospective national multicentric cohort study was conducted, including all ischemic stroke patients treated with endovascular treatment in mainland Portugal over two years (July 2015 to June 2017). All endovascular treatment centers contributed to an anonymized database. Demographic, stroke-related and procedure-related variables were collected. Crude endovascular treatment rates were calculated per 100 000 inhabitants for mainland Portugal, and each district and endovascular treatment standardized ratios (indirect age-sex standardization) were also calculated. Patient time metrics were computed as the median time between stroke onset, first-door, and puncture.Results: A total of 1625 endovascular treatment procedures were registered. The endovascular treatment rate was 8.27/100 000 inhabitants/year. We found regional heterogeneity in endovascular treatment rates (1.58 to 16.53/100 000/year), with higher rates in districts closer to endovascular treatment centers. When analyzed by district, the median time from stroke onset to puncture ranged from 212 to 432 minutes, reflecting regional heterogeneity.Conclusion: The overall national rate of EVT in the first two years after the organization of EVT-capable centers is one of the highest among European countries, however, significant regional disparities were documented. Moreover, stroke-onset-to-first-door times and in-hospital procedural times in the EVT centers were comparable to those reported in the randomized controlled trials performed in high-volume tertiary hospitals. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-02-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15031 |
url |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15031 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15031 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15031/6436 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15031/6437 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/15031/6438 |
dc.rights.driver.fl_str_mv |
Direitos de Autor (c) 2021 Acta Médica Portuguesa info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Direitos de Autor (c) 2021 Acta Médica Portuguesa |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
Ordem dos Médicos |
publisher.none.fl_str_mv |
Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 35 No. 2 (2022): February; 127-134 Acta Médica Portuguesa; Vol. 35 N.º 2 (2022): Fevereiro; 127-134 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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