Rare Case of Sarcomatoid Squamous Cell Carcinoma Arising in an Ovarian Mature Teratoma

Detalhes bibliográficos
Autor(a) principal: Sousa Pedrosa, I
Data de Publicação: 2019
Outros Autores: Alpendre, F, Sousa, R, Raposo Dinis, S, Gomes, D
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.17/3354
Resumo: Although mature cystic teratoma (MCT) is benign, malignant transformation (MT) occurs in ∼ 1% to 2% of all cases, and usually consists of squamous cell carcinoma (SCC), which accounts for ∼ 80% of the cases. Spindle-cell (sarcomatoid) carcinoma (SCSC) is an uncommon type of SCC, comprising up to 3% of all cases. The lack of characteristic symptoms and specific imaging findings may lead to preoperative misdiagnosis. Moreover, the clinicopathologic characteristics, the treatment, the prognostic factors and the mechanism of MT have not yet been well understood due to the rarity of such tumors, especially in women of reproductive age. The authors present a case of a 34-year-old patient with 14 weeks of gestation who was diagnosed with an adnexal mass suggestive of ovarian teratoma. A laparoscopy salpingo-oophorectomy was performed after 6 months of delivery, and the histological exam revealed a sarcomatoid SCC in the MCT.
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spelling Rare Case of Sarcomatoid Squamous Cell Carcinoma Arising in an Ovarian Mature TeratomaMAC OBSAdultFemaleHumansCarcinoma, Squamous Cell / diagnostic imagingCarcinoma, Squamous Cell / pathologyCarcinoma, Squamous Cell / surgeryFertility PreservationOvarian Neoplasms / diagnostic imagingOvarian Neoplasms / pathologyOvarian Neoplasms / surgeryOvary / diagnostic imagingOvary / pathologyOvary / surgeryPregnancyTeratoma / diagnostic imagingTeratoma / pathologyTeratoma / surgeryTime-to-TreatmentAlthough mature cystic teratoma (MCT) is benign, malignant transformation (MT) occurs in ∼ 1% to 2% of all cases, and usually consists of squamous cell carcinoma (SCC), which accounts for ∼ 80% of the cases. Spindle-cell (sarcomatoid) carcinoma (SCSC) is an uncommon type of SCC, comprising up to 3% of all cases. The lack of characteristic symptoms and specific imaging findings may lead to preoperative misdiagnosis. Moreover, the clinicopathologic characteristics, the treatment, the prognostic factors and the mechanism of MT have not yet been well understood due to the rarity of such tumors, especially in women of reproductive age. The authors present a case of a 34-year-old patient with 14 weeks of gestation who was diagnosed with an adnexal mass suggestive of ovarian teratoma. A laparoscopy salpingo-oophorectomy was performed after 6 months of delivery, and the histological exam revealed a sarcomatoid SCC in the MCT.Thieme OpenRepositório do Centro Hospitalar Universitário de Lisboa Central, EPESousa Pedrosa, IAlpendre, FSousa, RRaposo Dinis, SGomes, D2019-11-12T15:36:33Z2019-102019-10-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/3354engRev Bras Ginecol Obstet. 2019 Oct;41(10):628-632.10.1055/s-0039-1698773info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:42:33Zoai:repositorio.chlc.min-saude.pt:10400.17/3354Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:20:40.299475Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Rare Case of Sarcomatoid Squamous Cell Carcinoma Arising in an Ovarian Mature Teratoma
title Rare Case of Sarcomatoid Squamous Cell Carcinoma Arising in an Ovarian Mature Teratoma
spellingShingle Rare Case of Sarcomatoid Squamous Cell Carcinoma Arising in an Ovarian Mature Teratoma
Sousa Pedrosa, I
MAC OBS
Adult
Female
Humans
Carcinoma, Squamous Cell / diagnostic imaging
Carcinoma, Squamous Cell / pathology
Carcinoma, Squamous Cell / surgery
Fertility Preservation
Ovarian Neoplasms / diagnostic imaging
Ovarian Neoplasms / pathology
Ovarian Neoplasms / surgery
Ovary / diagnostic imaging
Ovary / pathology
Ovary / surgery
Pregnancy
Teratoma / diagnostic imaging
Teratoma / pathology
Teratoma / surgery
Time-to-Treatment
title_short Rare Case of Sarcomatoid Squamous Cell Carcinoma Arising in an Ovarian Mature Teratoma
title_full Rare Case of Sarcomatoid Squamous Cell Carcinoma Arising in an Ovarian Mature Teratoma
title_fullStr Rare Case of Sarcomatoid Squamous Cell Carcinoma Arising in an Ovarian Mature Teratoma
title_full_unstemmed Rare Case of Sarcomatoid Squamous Cell Carcinoma Arising in an Ovarian Mature Teratoma
title_sort Rare Case of Sarcomatoid Squamous Cell Carcinoma Arising in an Ovarian Mature Teratoma
author Sousa Pedrosa, I
author_facet Sousa Pedrosa, I
Alpendre, F
Sousa, R
Raposo Dinis, S
Gomes, D
author_role author
author2 Alpendre, F
Sousa, R
Raposo Dinis, S
Gomes, D
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE
dc.contributor.author.fl_str_mv Sousa Pedrosa, I
Alpendre, F
Sousa, R
Raposo Dinis, S
Gomes, D
dc.subject.por.fl_str_mv MAC OBS
Adult
Female
Humans
Carcinoma, Squamous Cell / diagnostic imaging
Carcinoma, Squamous Cell / pathology
Carcinoma, Squamous Cell / surgery
Fertility Preservation
Ovarian Neoplasms / diagnostic imaging
Ovarian Neoplasms / pathology
Ovarian Neoplasms / surgery
Ovary / diagnostic imaging
Ovary / pathology
Ovary / surgery
Pregnancy
Teratoma / diagnostic imaging
Teratoma / pathology
Teratoma / surgery
Time-to-Treatment
topic MAC OBS
Adult
Female
Humans
Carcinoma, Squamous Cell / diagnostic imaging
Carcinoma, Squamous Cell / pathology
Carcinoma, Squamous Cell / surgery
Fertility Preservation
Ovarian Neoplasms / diagnostic imaging
Ovarian Neoplasms / pathology
Ovarian Neoplasms / surgery
Ovary / diagnostic imaging
Ovary / pathology
Ovary / surgery
Pregnancy
Teratoma / diagnostic imaging
Teratoma / pathology
Teratoma / surgery
Time-to-Treatment
description Although mature cystic teratoma (MCT) is benign, malignant transformation (MT) occurs in ∼ 1% to 2% of all cases, and usually consists of squamous cell carcinoma (SCC), which accounts for ∼ 80% of the cases. Spindle-cell (sarcomatoid) carcinoma (SCSC) is an uncommon type of SCC, comprising up to 3% of all cases. The lack of characteristic symptoms and specific imaging findings may lead to preoperative misdiagnosis. Moreover, the clinicopathologic characteristics, the treatment, the prognostic factors and the mechanism of MT have not yet been well understood due to the rarity of such tumors, especially in women of reproductive age. The authors present a case of a 34-year-old patient with 14 weeks of gestation who was diagnosed with an adnexal mass suggestive of ovarian teratoma. A laparoscopy salpingo-oophorectomy was performed after 6 months of delivery, and the histological exam revealed a sarcomatoid SCC in the MCT.
publishDate 2019
dc.date.none.fl_str_mv 2019-11-12T15:36:33Z
2019-10
2019-10-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.17/3354
url http://hdl.handle.net/10400.17/3354
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Rev Bras Ginecol Obstet. 2019 Oct;41(10):628-632.
10.1055/s-0039-1698773
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Thieme Open
publisher.none.fl_str_mv Thieme Open
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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