Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 with grinch
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.18/8059 |
Resumo: | Late in 2020, two genetically-distinct clusters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with mutations of biological concern were reported, one in the United Kingdom and one in South Africa. Using a combination of data from routine surveillance, genomic sequencing and international travel we track the international dispersal of lineages B.1.1.7 and B.1.351 (variant 501Y-V2). We account for potential biases in genomic surveillance efforts by including passenger volumes from location of where the lineage was first reported, London and South Africa respectively. Using the software tool grinch (global report investigating novel coronavirus haplotypes), we track the international spread of lineages of concern with automated daily reports, Further, we have built a custom tracking website (cov-lineages.org/global_report.html) which hosts this daily report and will continue to include novel SARS-CoV-2 lineages of concern as they are detected. |
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Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 with grinchB.1.1.7; B.1.351N501YSARS-CoV-2Air TravelCoronavirusGenome SequencingGenomic EpidemiologyGenomic SurveillanceGenomicsPandemicSequencingSurveillanceVirusCOVID-19Infecções RespiratóriasLate in 2020, two genetically-distinct clusters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with mutations of biological concern were reported, one in the United Kingdom and one in South Africa. Using a combination of data from routine surveillance, genomic sequencing and international travel we track the international dispersal of lineages B.1.1.7 and B.1.351 (variant 501Y-V2). We account for potential biases in genomic surveillance efforts by including passenger volumes from location of where the lineage was first reported, London and South Africa respectively. Using the software tool grinch (global report investigating novel coronavirus haplotypes), we track the international spread of lineages of concern with automated daily reports, Further, we have built a custom tracking website (cov-lineages.org/global_report.html) which hosts this daily report and will continue to include novel SARS-CoV-2 lineages of concern as they are detected.I.I.B. is supported by the Canadian Institutes of Health Research, COVID-19 Rapid Research Funding Opportunity (02179-000). K.K. is the founder of BlueDot, a social enterprise that develops digital technologies for public health. K.K., A.W., A.T.B. and C.H. are employed at BlueDot. I.I.B. has consulted for BlueDot. T.d.O. and the NGS-SA is funded by the South African Medical Research Council (SAMRC), MRC SHIP and the Department of Science and Innovation (DSI) of South Africa. N.R.F. acknowledges support from a Wellcome Trust and Royal Society Sir Henry Dale Fellowship (204311/Z/16/Z) and a Medical Research Council-São Paulo Research Foundation CADDE partnership award (MR/S0195/1 and FAPESP 18/14389-0). VH was supported by the Biotechnology and Biological Sciences Research Council (BBSRC) [grant number BB/M010996/1]. M.U.G.K. acknowledges support from the Branco Weiss Fellowship and EU grant 874850 MOOD. O.G.P. , J.P.M. and M.U.G.K. acknowledge support from the Oxford Martin School. AR acknowledges the support of the Wellcome Trust (Collaborators Award 206298/Z/17/Z – ARTIC network) and the European Research Council (grant agreement no. 725422 – ReservoirDOCS). A.OT is supported by the Wellcome Trust Hosts, Pathogens & Global Health Programme [grant number: grant.203783/Z/16/Z] and Fast Grants [award number: 2236]. COG-UK is supported by funding from the Medical Research Council (MRC) part of UK Research & Innovation (UKRI), the National Institute of Health Research (NIHR) and Genome Research Limited, operating as the Wellcome Sanger Institute.TFS acknowledges support from the Deutsche Forschungsgemeinschaft (SFB900, EXC2155 RESIST). SeqCOVID-SPAIN is supported by a grant from the Instituto de Salud Carlos III COV0020/00140.F1000ResearchRepositório Científico do Instituto Nacional de SaúdeO'Toole, ÁineHill, VerityPybus, Oliver G.Watts, AlexanderBogoch, Issac I.Khan, KamranMessina, Jane P.Tegally, HouriiyahLessells, Richard R.Giandhari, JenniferPillay, SureshneeTumedi, Kefentse ArnoldNyepetsi, GapeKebabonye, MalebogoMatsheka, MaitshwareloMine, MadisaTokajian, SimaHassan, HamadSalloum, TamaraMerhi, GeorgiKoweyes, JadGeoghegan, Jemma L.de Ligt, JoepRen, XiaoyunStorey, MatthewFreed, Nikki E.Pattabiraman, ChitraPrasad, PramadaDesai, Anita S.Vasanthapuram, RaviSchulz, Thomas F.Steinbrück, LarsStadler, TanjaParisi, AntonioBianco, AngelicaGarcía de Viedma, DaríoBuenestado-Serrano, SergioBorges, VítorIsidro, JoanaDuarte, SílviaGomes, João PauloZuckerman, Neta S.Mandelboim, MichalMor, OrnaSeemann, TorstenArnott, AliciaDraper, JennyGall, MailieRawlinson, WilliamDeveson, IraSchlebusch, SanmariéMcMahon, JamieLeong, LexLim, Chuan KokChironna, MariaLoconsole, DanielaBal, AntoninJosset, LaurenceHolmes, EdwardSt. George, KirstenLasek-Nesselquist, EricaSikkema, Reina S.Oude Munnink, BasKoopmans, MarionBrytting, MiaSudha rani, V.Pavani, S.Smura, TeemuHeim, AlbertKurkela, SatuUmair, MassabSalman, MuhammadBartolini, BarbaraRueca, MartinaDrosten, ChristianWolff, ThorstenSilander, OlinEggink, DirkReusken, ChantalVennema, HarryPark, AekyungCarrington, ChristineSahadeo, NikitaCarr, MichaelGonzalez, Gabode Oliveira, TulioFaria, NunoRambaut, AndrewKraemer, Moritz U.G.2022-07-05T15:12:38Z2021-09-172021-09-17T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/8059engWellcome Open Res. 2021 Sep 17;6:121. doi: 10.12688/wellcomeopenres.16661.2. eCollection 20212398-502X10.12688/wellcomeopenres.16661.2info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:42:25Zoai:repositorio.insa.pt:10400.18/8059Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:42:50.579597Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 with grinch |
title |
Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 with grinch |
spellingShingle |
Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 with grinch O'Toole, Áine B.1.1.7; B.1.351 N501Y SARS-CoV-2 Air Travel Coronavirus Genome Sequencing Genomic Epidemiology Genomic Surveillance Genomics Pandemic Sequencing Surveillance Virus COVID-19 Infecções Respiratórias |
title_short |
Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 with grinch |
title_full |
Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 with grinch |
title_fullStr |
Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 with grinch |
title_full_unstemmed |
Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 with grinch |
title_sort |
Tracking the international spread of SARS-CoV-2 lineages B.1.1.7 and B.1.351/501Y-V2 with grinch |
author |
O'Toole, Áine |
author_facet |
O'Toole, Áine Hill, Verity Pybus, Oliver G. Watts, Alexander Bogoch, Issac I. Khan, Kamran Messina, Jane P. Tegally, Houriiyah Lessells, Richard R. Giandhari, Jennifer Pillay, Sureshnee Tumedi, Kefentse Arnold Nyepetsi, Gape Kebabonye, Malebogo Matsheka, Maitshwarelo Mine, Madisa Tokajian, Sima Hassan, Hamad Salloum, Tamara Merhi, Georgi Koweyes, Jad Geoghegan, Jemma L. de Ligt, Joep Ren, Xiaoyun Storey, Matthew Freed, Nikki E. Pattabiraman, Chitra Prasad, Pramada Desai, Anita S. Vasanthapuram, Ravi Schulz, Thomas F. Steinbrück, Lars Stadler, Tanja Parisi, Antonio Bianco, Angelica García de Viedma, Darío Buenestado-Serrano, Sergio Borges, Vítor Isidro, Joana Duarte, Sílvia Gomes, João Paulo Zuckerman, Neta S. Mandelboim, Michal Mor, Orna Seemann, Torsten Arnott, Alicia Draper, Jenny Gall, Mailie Rawlinson, William Deveson, Ira Schlebusch, Sanmarié McMahon, Jamie Leong, Lex Lim, Chuan Kok Chironna, Maria Loconsole, Daniela Bal, Antonin Josset, Laurence Holmes, Edward St. George, Kirsten Lasek-Nesselquist, Erica Sikkema, Reina S. Oude Munnink, Bas Koopmans, Marion Brytting, Mia Sudha rani, V. Pavani, S. Smura, Teemu Heim, Albert Kurkela, Satu Umair, Massab Salman, Muhammad Bartolini, Barbara Rueca, Martina Drosten, Christian Wolff, Thorsten Silander, Olin Eggink, Dirk Reusken, Chantal Vennema, Harry Park, Aekyung Carrington, Christine Sahadeo, Nikita Carr, Michael Gonzalez, Gabo de Oliveira, Tulio Faria, Nuno Rambaut, Andrew Kraemer, Moritz U.G. |
author_role |
author |
author2 |
Hill, Verity Pybus, Oliver G. Watts, Alexander Bogoch, Issac I. Khan, Kamran Messina, Jane P. Tegally, Houriiyah Lessells, Richard R. Giandhari, Jennifer Pillay, Sureshnee Tumedi, Kefentse Arnold Nyepetsi, Gape Kebabonye, Malebogo Matsheka, Maitshwarelo Mine, Madisa Tokajian, Sima Hassan, Hamad Salloum, Tamara Merhi, Georgi Koweyes, Jad Geoghegan, Jemma L. de Ligt, Joep Ren, Xiaoyun Storey, Matthew Freed, Nikki E. Pattabiraman, Chitra Prasad, Pramada Desai, Anita S. Vasanthapuram, Ravi Schulz, Thomas F. Steinbrück, Lars Stadler, Tanja Parisi, Antonio Bianco, Angelica García de Viedma, Darío Buenestado-Serrano, Sergio Borges, Vítor Isidro, Joana Duarte, Sílvia Gomes, João Paulo Zuckerman, Neta S. Mandelboim, Michal Mor, Orna Seemann, Torsten Arnott, Alicia Draper, Jenny Gall, Mailie Rawlinson, William Deveson, Ira Schlebusch, Sanmarié McMahon, Jamie Leong, Lex Lim, Chuan Kok Chironna, Maria Loconsole, Daniela Bal, Antonin Josset, Laurence Holmes, Edward St. George, Kirsten Lasek-Nesselquist, Erica Sikkema, Reina S. Oude Munnink, Bas Koopmans, Marion Brytting, Mia Sudha rani, V. Pavani, S. Smura, Teemu Heim, Albert Kurkela, Satu Umair, Massab Salman, Muhammad Bartolini, Barbara Rueca, Martina Drosten, Christian Wolff, Thorsten Silander, Olin Eggink, Dirk Reusken, Chantal Vennema, Harry Park, Aekyung Carrington, Christine Sahadeo, Nikita Carr, Michael Gonzalez, Gabo de Oliveira, Tulio Faria, Nuno Rambaut, Andrew Kraemer, Moritz U.G. |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Repositório Científico do Instituto Nacional de Saúde |
dc.contributor.author.fl_str_mv |
O'Toole, Áine Hill, Verity Pybus, Oliver G. Watts, Alexander Bogoch, Issac I. Khan, Kamran Messina, Jane P. Tegally, Houriiyah Lessells, Richard R. Giandhari, Jennifer Pillay, Sureshnee Tumedi, Kefentse Arnold Nyepetsi, Gape Kebabonye, Malebogo Matsheka, Maitshwarelo Mine, Madisa Tokajian, Sima Hassan, Hamad Salloum, Tamara Merhi, Georgi Koweyes, Jad Geoghegan, Jemma L. de Ligt, Joep Ren, Xiaoyun Storey, Matthew Freed, Nikki E. Pattabiraman, Chitra Prasad, Pramada Desai, Anita S. Vasanthapuram, Ravi Schulz, Thomas F. Steinbrück, Lars Stadler, Tanja Parisi, Antonio Bianco, Angelica García de Viedma, Darío Buenestado-Serrano, Sergio Borges, Vítor Isidro, Joana Duarte, Sílvia Gomes, João Paulo Zuckerman, Neta S. Mandelboim, Michal Mor, Orna Seemann, Torsten Arnott, Alicia Draper, Jenny Gall, Mailie Rawlinson, William Deveson, Ira Schlebusch, Sanmarié McMahon, Jamie Leong, Lex Lim, Chuan Kok Chironna, Maria Loconsole, Daniela Bal, Antonin Josset, Laurence Holmes, Edward St. George, Kirsten Lasek-Nesselquist, Erica Sikkema, Reina S. Oude Munnink, Bas Koopmans, Marion Brytting, Mia Sudha rani, V. Pavani, S. Smura, Teemu Heim, Albert Kurkela, Satu Umair, Massab Salman, Muhammad Bartolini, Barbara Rueca, Martina Drosten, Christian Wolff, Thorsten Silander, Olin Eggink, Dirk Reusken, Chantal Vennema, Harry Park, Aekyung Carrington, Christine Sahadeo, Nikita Carr, Michael Gonzalez, Gabo de Oliveira, Tulio Faria, Nuno Rambaut, Andrew Kraemer, Moritz U.G. |
dc.subject.por.fl_str_mv |
B.1.1.7; B.1.351 N501Y SARS-CoV-2 Air Travel Coronavirus Genome Sequencing Genomic Epidemiology Genomic Surveillance Genomics Pandemic Sequencing Surveillance Virus COVID-19 Infecções Respiratórias |
topic |
B.1.1.7; B.1.351 N501Y SARS-CoV-2 Air Travel Coronavirus Genome Sequencing Genomic Epidemiology Genomic Surveillance Genomics Pandemic Sequencing Surveillance Virus COVID-19 Infecções Respiratórias |
description |
Late in 2020, two genetically-distinct clusters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with mutations of biological concern were reported, one in the United Kingdom and one in South Africa. Using a combination of data from routine surveillance, genomic sequencing and international travel we track the international dispersal of lineages B.1.1.7 and B.1.351 (variant 501Y-V2). We account for potential biases in genomic surveillance efforts by including passenger volumes from location of where the lineage was first reported, London and South Africa respectively. Using the software tool grinch (global report investigating novel coronavirus haplotypes), we track the international spread of lineages of concern with automated daily reports, Further, we have built a custom tracking website (cov-lineages.org/global_report.html) which hosts this daily report and will continue to include novel SARS-CoV-2 lineages of concern as they are detected. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-09-17 2021-09-17T00:00:00Z 2022-07-05T15:12:38Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.18/8059 |
url |
http://hdl.handle.net/10400.18/8059 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Wellcome Open Res. 2021 Sep 17;6:121. doi: 10.12688/wellcomeopenres.16661.2. eCollection 2021 2398-502X 10.12688/wellcomeopenres.16661.2 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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F1000Research |
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F1000Research |
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