Chronic spontaneous urticaria in pediatric age

Detalhes bibliográficos
Autor(a) principal: Machado Cunha, Inês
Data de Publicação: 2020
Outros Autores: Rebelo Gomes, Eva
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.16/2574
Resumo: Introduction: Chronic spontaneous urticaria is characterized by emergence of pruritic maculopapular cutaneous lesions recurring for more than six weeks, without known triggering factor. Association with autoimmunity is sometimes present, with urticaria preceding the onset of autoimmune disease. Clinical case: A five-year-old female with a personal history of allergic asthma and family history of thyroid disease was referred to the Immunoallergology consultation for cutaneous complaints compatible with urticaria with more than three years of evolution. Inducible urticaria forms were excluded. Analytical study revealed positive antinuclear antibodies with a 1/320 titer and positive basophil activation test after stimulation with autologous serum. Control of cutaneous manifestations was achieved with full dose antihistaminic H1. Conclusion: Chronic spontaneous urticaria associated with autoimmunity is rare in children. Clinical follow-up should be maintained to evaluate disease control and enable early recognition of other autoimmunity manifestations.
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spelling Chronic spontaneous urticaria in pediatric ageUrticária crónica espontânea em idade pediátricaautoimmune urticariachildchronic spontaneous urticariadiagnostic investigationIntroduction: Chronic spontaneous urticaria is characterized by emergence of pruritic maculopapular cutaneous lesions recurring for more than six weeks, without known triggering factor. Association with autoimmunity is sometimes present, with urticaria preceding the onset of autoimmune disease. Clinical case: A five-year-old female with a personal history of allergic asthma and family history of thyroid disease was referred to the Immunoallergology consultation for cutaneous complaints compatible with urticaria with more than three years of evolution. Inducible urticaria forms were excluded. Analytical study revealed positive antinuclear antibodies with a 1/320 titer and positive basophil activation test after stimulation with autologous serum. Control of cutaneous manifestations was achieved with full dose antihistaminic H1. Conclusion: Chronic spontaneous urticaria associated with autoimmunity is rare in children. Clinical follow-up should be maintained to evaluate disease control and enable early recognition of other autoimmunity manifestations.Centro Hospitalar Universitário do PortoRepositório Científico do Centro Hospitalar Universitário de Santo AntónioMachado Cunha, InêsRebelo Gomes, Eva2021-11-18T10:42:23Z2020-092020-09-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.16/2574engMachado-Cunha I, Rebelo-Gomes E, Nascer e Crescer - Birth and Growth Medical Journal 2020;29(3): 145-148. doi:10.25753/BirthGrowthMJ.v29.i3.170022183-941710.25753/BirthGrowthMJ.v29.i3.17002info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-10-20T11:01:09Zoai:repositorio.chporto.pt:10400.16/2574Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:38:46.340380Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Chronic spontaneous urticaria in pediatric age
Urticária crónica espontânea em idade pediátrica
title Chronic spontaneous urticaria in pediatric age
spellingShingle Chronic spontaneous urticaria in pediatric age
Machado Cunha, Inês
autoimmune urticaria
child
chronic spontaneous urticaria
diagnostic investigation
title_short Chronic spontaneous urticaria in pediatric age
title_full Chronic spontaneous urticaria in pediatric age
title_fullStr Chronic spontaneous urticaria in pediatric age
title_full_unstemmed Chronic spontaneous urticaria in pediatric age
title_sort Chronic spontaneous urticaria in pediatric age
author Machado Cunha, Inês
author_facet Machado Cunha, Inês
Rebelo Gomes, Eva
author_role author
author2 Rebelo Gomes, Eva
author2_role author
dc.contributor.none.fl_str_mv Repositório Científico do Centro Hospitalar Universitário de Santo António
dc.contributor.author.fl_str_mv Machado Cunha, Inês
Rebelo Gomes, Eva
dc.subject.por.fl_str_mv autoimmune urticaria
child
chronic spontaneous urticaria
diagnostic investigation
topic autoimmune urticaria
child
chronic spontaneous urticaria
diagnostic investigation
description Introduction: Chronic spontaneous urticaria is characterized by emergence of pruritic maculopapular cutaneous lesions recurring for more than six weeks, without known triggering factor. Association with autoimmunity is sometimes present, with urticaria preceding the onset of autoimmune disease. Clinical case: A five-year-old female with a personal history of allergic asthma and family history of thyroid disease was referred to the Immunoallergology consultation for cutaneous complaints compatible with urticaria with more than three years of evolution. Inducible urticaria forms were excluded. Analytical study revealed positive antinuclear antibodies with a 1/320 titer and positive basophil activation test after stimulation with autologous serum. Control of cutaneous manifestations was achieved with full dose antihistaminic H1. Conclusion: Chronic spontaneous urticaria associated with autoimmunity is rare in children. Clinical follow-up should be maintained to evaluate disease control and enable early recognition of other autoimmunity manifestations.
publishDate 2020
dc.date.none.fl_str_mv 2020-09
2020-09-01T00:00:00Z
2021-11-18T10:42:23Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.16/2574
url http://hdl.handle.net/10400.16/2574
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Machado-Cunha I, Rebelo-Gomes E, Nascer e Crescer - Birth and Growth Medical Journal 2020;29(3): 145-148. doi:10.25753/BirthGrowthMJ.v29.i3.17002
2183-9417
10.25753/BirthGrowthMJ.v29.i3.17002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Centro Hospitalar Universitário do Porto
publisher.none.fl_str_mv Centro Hospitalar Universitário do Porto
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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