Determinants for hospitalisations, intensive care unit admission and death among 20,293 reported COVID-19 cases in Portugal, March to April 2020

Detalhes bibliográficos
Autor(a) principal: Peixoto, Vasco Ricoca
Data de Publicação: 2021
Outros Autores: Vieira, André, Aguiar, Pedro, Sousa, Paulo, Carvalho, Carlos, Thomas, Daniel, Abrantes, Alexandre, Nunes, Carla
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/125708
Resumo: Publisher Copyright: © 2021 European Centre for Disease Prevention and Control (ECDC). All rights reserved.
id RCAP_ca47ce3fbf9aa347824b1c61d2982eea
oai_identifier_str oai:run.unl.pt:10362/125708
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Determinants for hospitalisations, intensive care unit admission and death among 20,293 reported COVID-19 cases in Portugal, March to April 2020EpidemiologyPublic Health, Environmental and Occupational HealthVirologySDG 3 - Good Health and Well-beingPublisher Copyright: © 2021 European Centre for Disease Prevention and Control (ECDC). All rights reserved.Background: Determinants of hospitalisation, intensive care unit (ICU) admission and death are still unclear for COVID-19. Few studies have adjusted for confounding for different clinical outcomes including all reported cases within a country. Aim: We used routine surveillance data from Portugal to identify risk factors for severe COVID-19 outcomes, and to support risk stratification, public health interventions, and planning of healthcare resources. Methods: We conducted a retrospective cohort study including 20,293 laboratory- confirmed cases of COVID-19 reported between 1 March and 28 April 2020 through the national epidemiological surveillance system. We calculated absolute risk, relative risk (RR) and adjusted relative risk (aRR) to identify demographic and clinical factors associated with hospitalisation, ICU admission and death using Poisson regressions. Results: Increasing age (≥ 60 years) was the major determinant for all outcomes. Age ≥ 90 years was the strongest determinant of hospital admission (aRR: 6.1), and 70-79 years for ICU (aRR: 10.4). Comorbidities of cardiovascular, immunodeficiency, kidney and lung disease (aRR: 4.3, 2.8, 2.4, 2.0, respectively) had stronger associations with ICU admission, while for death they were kidney, cardiovascular and chronic neurological disease (aRR: 2.9, 2.6, 2.0). Conclusions: Older age was the strongest risk factor for all severe outcomes. These findings from the early stages of the COVID-19 pandemic support risk-stratified public health measures that should prioritise protecting older people. Epidemiological scenarios and clinical guidelines should consider this, even though under-ascertainment should also be considered.Comprehensive Health Research Centre (CHRC) - Pólo ENSPEscola Nacional de Saúde Pública (ENSP)Centro de Investigação em Saúde Pública (CISP/PHRC)RUNPeixoto, Vasco RicocaVieira, AndréAguiar, PedroSousa, PauloCarvalho, CarlosThomas, DanielAbrantes, AlexandreNunes, Carla2021-10-06T23:21:53Z2021-08-192021-08-19T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/125708eng1025-496XPURE: 34123055https://doi.org/10.2807/1560-7917.ES.2021.26.33.2001059info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:06:33Zoai:run.unl.pt:10362/125708Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:45:45.491982Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Determinants for hospitalisations, intensive care unit admission and death among 20,293 reported COVID-19 cases in Portugal, March to April 2020
title Determinants for hospitalisations, intensive care unit admission and death among 20,293 reported COVID-19 cases in Portugal, March to April 2020
spellingShingle Determinants for hospitalisations, intensive care unit admission and death among 20,293 reported COVID-19 cases in Portugal, March to April 2020
Peixoto, Vasco Ricoca
Epidemiology
Public Health, Environmental and Occupational Health
Virology
SDG 3 - Good Health and Well-being
title_short Determinants for hospitalisations, intensive care unit admission and death among 20,293 reported COVID-19 cases in Portugal, March to April 2020
title_full Determinants for hospitalisations, intensive care unit admission and death among 20,293 reported COVID-19 cases in Portugal, March to April 2020
title_fullStr Determinants for hospitalisations, intensive care unit admission and death among 20,293 reported COVID-19 cases in Portugal, March to April 2020
title_full_unstemmed Determinants for hospitalisations, intensive care unit admission and death among 20,293 reported COVID-19 cases in Portugal, March to April 2020
title_sort Determinants for hospitalisations, intensive care unit admission and death among 20,293 reported COVID-19 cases in Portugal, March to April 2020
author Peixoto, Vasco Ricoca
author_facet Peixoto, Vasco Ricoca
Vieira, André
Aguiar, Pedro
Sousa, Paulo
Carvalho, Carlos
Thomas, Daniel
Abrantes, Alexandre
Nunes, Carla
author_role author
author2 Vieira, André
Aguiar, Pedro
Sousa, Paulo
Carvalho, Carlos
Thomas, Daniel
Abrantes, Alexandre
Nunes, Carla
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Comprehensive Health Research Centre (CHRC) - Pólo ENSP
Escola Nacional de Saúde Pública (ENSP)
Centro de Investigação em Saúde Pública (CISP/PHRC)
RUN
dc.contributor.author.fl_str_mv Peixoto, Vasco Ricoca
Vieira, André
Aguiar, Pedro
Sousa, Paulo
Carvalho, Carlos
Thomas, Daniel
Abrantes, Alexandre
Nunes, Carla
dc.subject.por.fl_str_mv Epidemiology
Public Health, Environmental and Occupational Health
Virology
SDG 3 - Good Health and Well-being
topic Epidemiology
Public Health, Environmental and Occupational Health
Virology
SDG 3 - Good Health and Well-being
description Publisher Copyright: © 2021 European Centre for Disease Prevention and Control (ECDC). All rights reserved.
publishDate 2021
dc.date.none.fl_str_mv 2021-10-06T23:21:53Z
2021-08-19
2021-08-19T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/125708
url http://hdl.handle.net/10362/125708
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1025-496X
PURE: 34123055
https://doi.org/10.2807/1560-7917.ES.2021.26.33.2001059
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799138062094041088

Registros relacionados