Late Preterm Newborns: Do We Already Know Everything About Them?

Detalhes bibliográficos
Autor(a) principal: Pereira, Miguel Paiva
Data de Publicação: 2022
Outros Autores: Esteves, Catarina, Fernandes, Cláudia, Ferreira, Ana Rute, Lucas, Mafalda, Rodrigues, Ana, Matos, Cristina, Serrão Neto, Ana
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.25754/pjp.2022.24957
Resumo: Introduction: The preterm birth rate is on the rise, and late preterm deliveries account for 75% of preterm deliveries. Late preterm newborns were for many years considered full-term newborns; however, their particularities have been recognized in the last decade, particularly in terms of the higher rate of complications in the neonatal period. This study aimed to analyze the factors associated with greater morbidity in late preterm newborns. Methods: In this cross-sectional study we reviewed the medical records of mothers and their late preterm infants born at our hospital during a four-year period. Logistic binary regression analysis was used to identify predictors of morbidity and control the confounding variables. Results: The study included 576 newborns, of whom 28% (n = 164) had some morbidities, the most common of which included respiratory distress syndrome and hyperbilirubinemia. The morbidity rate varied inversely with gestational age. A lower gesta- tional age, being small for gestational age, and the incomplete use of antenatal corticosteroids were identified as risk factors for morbidities (p < 0.01). Antenatal corticosteroids were apparently more used on the newborns who later developed respiratory distress syndrome (p < 0.01). In contrast, type of delivery, medically assisted reproduction, and pregnancy morbidity did not influence neonatal morbidity. Discussion: Some well-known risk factors were confirmed for neonatal morbidity; however, there was no evidence to confirm the association between other determinants mentioned in previous studies and the increased risk of morbidity in our study samples, such as cesarean section, gemelarity, or fetal growth restriction.
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spelling Late Preterm Newborns: Do We Already Know Everything About Them?Original articlesIntroduction: The preterm birth rate is on the rise, and late preterm deliveries account for 75% of preterm deliveries. Late preterm newborns were for many years considered full-term newborns; however, their particularities have been recognized in the last decade, particularly in terms of the higher rate of complications in the neonatal period. This study aimed to analyze the factors associated with greater morbidity in late preterm newborns. Methods: In this cross-sectional study we reviewed the medical records of mothers and their late preterm infants born at our hospital during a four-year period. Logistic binary regression analysis was used to identify predictors of morbidity and control the confounding variables. Results: The study included 576 newborns, of whom 28% (n = 164) had some morbidities, the most common of which included respiratory distress syndrome and hyperbilirubinemia. The morbidity rate varied inversely with gestational age. A lower gesta- tional age, being small for gestational age, and the incomplete use of antenatal corticosteroids were identified as risk factors for morbidities (p < 0.01). Antenatal corticosteroids were apparently more used on the newborns who later developed respiratory distress syndrome (p < 0.01). In contrast, type of delivery, medically assisted reproduction, and pregnancy morbidity did not influence neonatal morbidity. Discussion: Some well-known risk factors were confirmed for neonatal morbidity; however, there was no evidence to confirm the association between other determinants mentioned in previous studies and the increased risk of morbidity in our study samples, such as cesarean section, gemelarity, or fetal growth restriction.Introdução: A taxa de nascimento prematuro está a aumentar, e os recém-nascidos prematuros tardios correspondem a 75% de todos os partos prematuros. Os recém-nascidos prematuros tardios foram durante muitos anos considerados como recém-nascidos de termo, mas na última década as suas especificidades foram reconhecidas, principalmente no que se refere ao maior índice de complicações no período neonatal. O nosso objetivo é analisar quais os fatores associados a maior morbilidade neonatal nesta população. Métodos: Realizámos um estudo de coorte com revisão dos registos médicos dos prematuros tardios (e respetivas mães) nascidos no nosso hospital durante um período de 4 anos. A análise de regressão logística binária foi usada para identificar preditores de morbidade e controlar as variáveis ​​confundidoras. Nível de significância considerado p <0,05. Resultados: Quinhentos e setenta e seis recém-nascidos foram incluídos. Destes, 28% (n = 164) apresentaram alguma morbilidade, sendo a síndrome de dificuldade respiratória e a hiperbilirrubinémia as mais frequentes. A taxa de morbilidade variou inversamente com a idade gestacional. Ter uma menor idade gestacional, ser leve para a idade gestacional e a utilização incompleta de corticoterapia pré-natal foram identificados como fatores de risco para morbilidade (p <0,01). A utilização de corticoterapia pré-natal aumentou a ocorrência de síndrome de dificuldade respiratória (p <0,01). Em contraste, o tipo de parto, reprodução medicamente assistida e morbilidade obstétrica não influenciaram a morbilidade neonatal. Discussão: Confirmámos alguns fatores de risco bem conhecidos para morbilidade neonatal, contudo, outros determinantes citados em estudos anteriores não apresentaram evidência relativamente ao aumento do risco de morbilidade na nossa amostra, como o parto por cesariana, a gemelaridade ou a restrição do crescimento fetal. Um achado relevante que merece investigação adicional é o impacto negativo da corticoterapia pré-natal na morbilidade respiratória.Sociedade Portuguesa de Pediatria2022-05-23info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.25754/pjp.2022.24957eng2184-44532184-3333Pereira, Miguel PaivaEsteves, CatarinaFernandes, CláudiaFerreira, Ana RuteLucas, MafaldaRodrigues, AnaMatos, CristinaSerrão Neto, Anainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-08-03T02:58:20Zoai:ojs.revistas.rcaap.pt:article/24957Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:25:38.988794Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Late Preterm Newborns: Do We Already Know Everything About Them?
title Late Preterm Newborns: Do We Already Know Everything About Them?
spellingShingle Late Preterm Newborns: Do We Already Know Everything About Them?
Pereira, Miguel Paiva
Original articles
title_short Late Preterm Newborns: Do We Already Know Everything About Them?
title_full Late Preterm Newborns: Do We Already Know Everything About Them?
title_fullStr Late Preterm Newborns: Do We Already Know Everything About Them?
title_full_unstemmed Late Preterm Newborns: Do We Already Know Everything About Them?
title_sort Late Preterm Newborns: Do We Already Know Everything About Them?
author Pereira, Miguel Paiva
author_facet Pereira, Miguel Paiva
Esteves, Catarina
Fernandes, Cláudia
Ferreira, Ana Rute
Lucas, Mafalda
Rodrigues, Ana
Matos, Cristina
Serrão Neto, Ana
author_role author
author2 Esteves, Catarina
Fernandes, Cláudia
Ferreira, Ana Rute
Lucas, Mafalda
Rodrigues, Ana
Matos, Cristina
Serrão Neto, Ana
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Pereira, Miguel Paiva
Esteves, Catarina
Fernandes, Cláudia
Ferreira, Ana Rute
Lucas, Mafalda
Rodrigues, Ana
Matos, Cristina
Serrão Neto, Ana
dc.subject.por.fl_str_mv Original articles
topic Original articles
description Introduction: The preterm birth rate is on the rise, and late preterm deliveries account for 75% of preterm deliveries. Late preterm newborns were for many years considered full-term newborns; however, their particularities have been recognized in the last decade, particularly in terms of the higher rate of complications in the neonatal period. This study aimed to analyze the factors associated with greater morbidity in late preterm newborns. Methods: In this cross-sectional study we reviewed the medical records of mothers and their late preterm infants born at our hospital during a four-year period. Logistic binary regression analysis was used to identify predictors of morbidity and control the confounding variables. Results: The study included 576 newborns, of whom 28% (n = 164) had some morbidities, the most common of which included respiratory distress syndrome and hyperbilirubinemia. The morbidity rate varied inversely with gestational age. A lower gesta- tional age, being small for gestational age, and the incomplete use of antenatal corticosteroids were identified as risk factors for morbidities (p < 0.01). Antenatal corticosteroids were apparently more used on the newborns who later developed respiratory distress syndrome (p < 0.01). In contrast, type of delivery, medically assisted reproduction, and pregnancy morbidity did not influence neonatal morbidity. Discussion: Some well-known risk factors were confirmed for neonatal morbidity; however, there was no evidence to confirm the association between other determinants mentioned in previous studies and the increased risk of morbidity in our study samples, such as cesarean section, gemelarity, or fetal growth restriction.
publishDate 2022
dc.date.none.fl_str_mv 2022-05-23
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