Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants

Detalhes bibliográficos
Autor(a) principal: P. Essoh, Anyse
Data de Publicação: 2022
Outros Autores: Liberal, Ângela, Fernandes, Ângela, Dias, Maria Inês, Pereira, Carla, Mandim, Filipa, Moldão-Martins, Margarida, Cravo, Pedro, Duarte, Maria Paula, Moura, Mónica, Romeiras, Maria M., Barros, Lillian
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/148589
Resumo: Funding Information: The authors are grateful to the Foundation for Science and Technology (FCT, Portugal) for financial support through national funds FCT/MCTES (PIDDAC) to CIMO (UIDB/00690/2020 and UIDP/00690/2020) and SusTEC (LA/P/0007/2021); National funding by FCT, P.I., through the individual scientific employment program contract for L. Barros, A. Fernandes, M.I. Dias and C. Pereira. This research was funded by Fundação para a Ciência e a Tecnologia (FCT) and Aga Khan Development Network (AKDN) under the project CVAgrobiodiversity/333111699. Publisher Copyright: © 2022 by the authors.
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spelling Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plantsbioactive propertiesCabo Verdeendemic medicinal plantstraditional medicineRM Therapeutics. PharmacologyRS Pharmacy and materia medicaRV Botanic, Thomsonian, and eclectic medicineMolecular MedicinePharmaceutical ScienceDrug DiscoverySDG 3 - Good Health and Well-beingSDG 12 - Responsible Consumption and ProductionFunding Information: The authors are grateful to the Foundation for Science and Technology (FCT, Portugal) for financial support through national funds FCT/MCTES (PIDDAC) to CIMO (UIDB/00690/2020 and UIDP/00690/2020) and SusTEC (LA/P/0007/2021); National funding by FCT, P.I., through the individual scientific employment program contract for L. Barros, A. Fernandes, M.I. Dias and C. Pereira. This research was funded by Fundação para a Ciência e a Tecnologia (FCT) and Aga Khan Development Network (AKDN) under the project CVAgrobiodiversity/333111699. Publisher Copyright: © 2022 by the authors.The use of medicinal plants in a variety of health conditions remains essential for the discovery of new treatments. The present study aimed to investigate the bioactive properties of three native plants from Cabo Verde Islands, namely Artemisia gorgonum Webb, Sideroxylon marginatum (Decne. ex Webb) Cout., and Tamarix senegalensis DC., contributing to the characterization of less-known medicinal plants and their potential benefits for human health. Known compounds, such as kaempferol, quercetin, caffeyolquinic, and apigenin derivatives, among others, were detected in the plant species under study. Overall, all species demonstrated good antioxidant capacity, especially the ethanolic extracts of A. gorgonum (EC50 = 0.149 mg/mL) in TBARS assay. Moreover, the ethanolic extracts of the studied plants showed cytotoxic properties against tumor cells, and again the A. gorgonum extract proved to be the most effective in inhibiting tumor growth, mainly in the CaCO2 (GI50 = 17.3 μg/mL) and AGS (GI50 = 18.2 μg/mL) cell lines. Only the ethanolic extracts of T. senegalensis and S. marginatum demonstrated anti-inflammatory activity, albeit weak (EC50 = 35 and 43 μg/mL, respectively). The present study contributed to increased knowledge about the bioactive properties of these plants commonly used in traditional medicine, some of which was discussed for the first time, opening new perspectives for their use in a wider range of health conditions, especially in African countries, where access to modern health care is more limited.Vector borne diseases and pathogens (VBD)Global Health and Tropical Medicine (GHTM)Instituto de Higiene e Medicina Tropical (IHMT)Universidade NOVA de LisboaMEtRICS - Centro de Engenharia Mecânica e Sustentabilidade de RecursosFaculdade de Ciências e Tecnologia (FCT)RUNP. Essoh, AnyseLiberal, ÂngelaFernandes, ÂngelaDias, Maria InêsPereira, CarlaMandim, FilipaMoldão-Martins, MargaridaCravo, PedroDuarte, Maria PaulaMoura, MónicaRomeiras, Maria M.Barros, Lillian2023-02-02T22:20:21Z2022-092022-09-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/148589eng1424-8247PURE: 50798936https://doi.org/10.3390/ph15091162info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:30:15Zoai:run.unl.pt:10362/148589Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:53:25.707133Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants
title Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants
spellingShingle Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants
P. Essoh, Anyse
bioactive properties
Cabo Verde
endemic medicinal plants
traditional medicine
RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
RV Botanic, Thomsonian, and eclectic medicine
Molecular Medicine
Pharmaceutical Science
Drug Discovery
SDG 3 - Good Health and Well-being
SDG 12 - Responsible Consumption and Production
title_short Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants
title_full Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants
title_fullStr Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants
title_full_unstemmed Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants
title_sort Evaluation of the Polyphenolic Composition and Bioactivities of Three Native Cabo Verde Medicinal Plants
author P. Essoh, Anyse
author_facet P. Essoh, Anyse
Liberal, Ângela
Fernandes, Ângela
Dias, Maria Inês
Pereira, Carla
Mandim, Filipa
Moldão-Martins, Margarida
Cravo, Pedro
Duarte, Maria Paula
Moura, Mónica
Romeiras, Maria M.
Barros, Lillian
author_role author
author2 Liberal, Ângela
Fernandes, Ângela
Dias, Maria Inês
Pereira, Carla
Mandim, Filipa
Moldão-Martins, Margarida
Cravo, Pedro
Duarte, Maria Paula
Moura, Mónica
Romeiras, Maria M.
Barros, Lillian
author2_role author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Vector borne diseases and pathogens (VBD)
Global Health and Tropical Medicine (GHTM)
Instituto de Higiene e Medicina Tropical (IHMT)
Universidade NOVA de Lisboa
MEtRICS - Centro de Engenharia Mecânica e Sustentabilidade de Recursos
Faculdade de Ciências e Tecnologia (FCT)
RUN
dc.contributor.author.fl_str_mv P. Essoh, Anyse
Liberal, Ângela
Fernandes, Ângela
Dias, Maria Inês
Pereira, Carla
Mandim, Filipa
Moldão-Martins, Margarida
Cravo, Pedro
Duarte, Maria Paula
Moura, Mónica
Romeiras, Maria M.
Barros, Lillian
dc.subject.por.fl_str_mv bioactive properties
Cabo Verde
endemic medicinal plants
traditional medicine
RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
RV Botanic, Thomsonian, and eclectic medicine
Molecular Medicine
Pharmaceutical Science
Drug Discovery
SDG 3 - Good Health and Well-being
SDG 12 - Responsible Consumption and Production
topic bioactive properties
Cabo Verde
endemic medicinal plants
traditional medicine
RM Therapeutics. Pharmacology
RS Pharmacy and materia medica
RV Botanic, Thomsonian, and eclectic medicine
Molecular Medicine
Pharmaceutical Science
Drug Discovery
SDG 3 - Good Health and Well-being
SDG 12 - Responsible Consumption and Production
description Funding Information: The authors are grateful to the Foundation for Science and Technology (FCT, Portugal) for financial support through national funds FCT/MCTES (PIDDAC) to CIMO (UIDB/00690/2020 and UIDP/00690/2020) and SusTEC (LA/P/0007/2021); National funding by FCT, P.I., through the individual scientific employment program contract for L. Barros, A. Fernandes, M.I. Dias and C. Pereira. This research was funded by Fundação para a Ciência e a Tecnologia (FCT) and Aga Khan Development Network (AKDN) under the project CVAgrobiodiversity/333111699. Publisher Copyright: © 2022 by the authors.
publishDate 2022
dc.date.none.fl_str_mv 2022-09
2022-09-01T00:00:00Z
2023-02-02T22:20:21Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/148589
url http://hdl.handle.net/10362/148589
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1424-8247
PURE: 50798936
https://doi.org/10.3390/ph15091162
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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