Therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: a case report
Autor(a) principal: | |
---|---|
Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Relatório |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692018000400010 |
Resumo: | Severe hypertriglyceridemia is defined as a serum triglyceride level >885mg/dl. It is an uncommon condition associated with serious complications, mainly acute pancreatitis. Treatment includes lifestyle changes, medical therapy and, more recently, extracorporeal apheresis techniques. Herein, we report a case of severe hypertriglyceridemia managed with therapeutic plasma exchange. Our patient presented with severe upper abdominal pain. Bloodwork showed extremely severe hypertriglyceridemia (14871mg/dl) and hypercholesterolemia (1536mg/dl) with only slight elevation of amylase and lipase and no echographic signs of acute pancreatitis. Two sessions of therapeutic plasma exchange were performed, with a mean 3L of plasma treated per session. The triglyceride levels dropped to 2325mg/dl after the first session and to 1207mg/dl after the second. Medical therapy was started, and the patient was discharged a week later. After 36 months of follow-up she remains stable, with triglyceride levels 427mg/dl. In this case therapeutic plasma exchange was an effective and well tolerated treatment for severe hypertriglyceridemia |
id |
RCAP_cfa495ba6433701b0241b9c45f0608fa |
---|---|
oai_identifier_str |
oai:scielo:S0872-01692018000400010 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
|
spelling |
Therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: a case reportHypertriglyceridemiaTherapeutic Plasma ExchangeAbdominal PainSevere hypertriglyceridemia is defined as a serum triglyceride level >885mg/dl. It is an uncommon condition associated with serious complications, mainly acute pancreatitis. Treatment includes lifestyle changes, medical therapy and, more recently, extracorporeal apheresis techniques. Herein, we report a case of severe hypertriglyceridemia managed with therapeutic plasma exchange. Our patient presented with severe upper abdominal pain. Bloodwork showed extremely severe hypertriglyceridemia (14871mg/dl) and hypercholesterolemia (1536mg/dl) with only slight elevation of amylase and lipase and no echographic signs of acute pancreatitis. Two sessions of therapeutic plasma exchange were performed, with a mean 3L of plasma treated per session. The triglyceride levels dropped to 2325mg/dl after the first session and to 1207mg/dl after the second. Medical therapy was started, and the patient was discharged a week later. After 36 months of follow-up she remains stable, with triglyceride levels 427mg/dl. In this case therapeutic plasma exchange was an effective and well tolerated treatment for severe hypertriglyceridemiaSociedade Portuguesa de Nefrologia2018-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/reporttext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692018000400010Portuguese Journal of Nephrology & Hypertension v.32 n.4 2018reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692018000400010Carvalho,Tiago JMartins,Ana RitaCalça,RitaTorres,João SousaGil,CéliaRodrigues,IlídioGaspar,Maria AugustaAdragão,TeresaBruges,Margaridainfo:eu-repo/semantics/openAccess2023-07-27T12:22:28ZPortal AgregadorONG |
dc.title.none.fl_str_mv |
Therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: a case report |
title |
Therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: a case report |
spellingShingle |
Therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: a case report Carvalho,Tiago J Hypertriglyceridemia Therapeutic Plasma Exchange Abdominal Pain |
title_short |
Therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: a case report |
title_full |
Therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: a case report |
title_fullStr |
Therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: a case report |
title_full_unstemmed |
Therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: a case report |
title_sort |
Therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: a case report |
author |
Carvalho,Tiago J |
author_facet |
Carvalho,Tiago J Martins,Ana Rita Calça,Rita Torres,João Sousa Gil,Célia Rodrigues,Ilídio Gaspar,Maria Augusta Adragão,Teresa Bruges,Margarida |
author_role |
author |
author2 |
Martins,Ana Rita Calça,Rita Torres,João Sousa Gil,Célia Rodrigues,Ilídio Gaspar,Maria Augusta Adragão,Teresa Bruges,Margarida |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Carvalho,Tiago J Martins,Ana Rita Calça,Rita Torres,João Sousa Gil,Célia Rodrigues,Ilídio Gaspar,Maria Augusta Adragão,Teresa Bruges,Margarida |
dc.subject.por.fl_str_mv |
Hypertriglyceridemia Therapeutic Plasma Exchange Abdominal Pain |
topic |
Hypertriglyceridemia Therapeutic Plasma Exchange Abdominal Pain |
description |
Severe hypertriglyceridemia is defined as a serum triglyceride level >885mg/dl. It is an uncommon condition associated with serious complications, mainly acute pancreatitis. Treatment includes lifestyle changes, medical therapy and, more recently, extracorporeal apheresis techniques. Herein, we report a case of severe hypertriglyceridemia managed with therapeutic plasma exchange. Our patient presented with severe upper abdominal pain. Bloodwork showed extremely severe hypertriglyceridemia (14871mg/dl) and hypercholesterolemia (1536mg/dl) with only slight elevation of amylase and lipase and no echographic signs of acute pancreatitis. Two sessions of therapeutic plasma exchange were performed, with a mean 3L of plasma treated per session. The triglyceride levels dropped to 2325mg/dl after the first session and to 1207mg/dl after the second. Medical therapy was started, and the patient was discharged a week later. After 36 months of follow-up she remains stable, with triglyceride levels 427mg/dl. In this case therapeutic plasma exchange was an effective and well tolerated treatment for severe hypertriglyceridemia |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-12-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/report |
format |
report |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692018000400010 |
url |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692018000400010 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692018000400010 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Nefrologia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Nefrologia |
dc.source.none.fl_str_mv |
Portuguese Journal of Nephrology & Hypertension v.32 n.4 2018 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
|
repository.mail.fl_str_mv |
|
_version_ |
1777304401768087552 |