Leprosy and Rheumatoid Arthritis: Consequence or Association?

Detalhes bibliográficos
Autor(a) principal: Coelho Henriques, C
Data de Publicação: 2012
Outros Autores: Lopéz, B, Mestre, T, Grima, B, Panarra, A, Riso, N
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.17/2986
Resumo: Leprosy or Hansen's disease is a chronic granulomatous infectious disease caused by Mycobacterium leprae with a high prevalence in some developing countries however, it is rarely seen in non-endemic regions. Arthritis has been described in all types of Hansen's disease. Chronic arthritis is known to exist even in paucibacillary forms, resolved or treated disease and in patients without reaction, suggesting a perpetuated inflammatory process. In these cases leprosy can mimic some autoimmune diseases such as rheumatoid arthritis. When a patient with a history of leprosy presents with a symmetric, distal, polyarthritis the diagnosis may not be linear. Possibly it is a rheumatoid-like leprous arthritis with M leprae acting as the trigger element for the chronic process or it is an overlap condition, with a concomitant rheumatoid arthritis? A case report of a patient with a chronic inflammatory arthritis with 10 years of evolution is presented. The differential diagnosis between leprous and rheumatoid arthritis is discussed.
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spelling Leprosy and Rheumatoid Arthritis: Consequence or Association?Antirheumatic AgentsArthritis, InfectiousArthritis, RheumatoidDiagnosis, DifferentialFemaleHumansLeprostatic AgentsLeprosyMiddle AgedHCC MEDHCC DERLeprosy or Hansen's disease is a chronic granulomatous infectious disease caused by Mycobacterium leprae with a high prevalence in some developing countries however, it is rarely seen in non-endemic regions. Arthritis has been described in all types of Hansen's disease. Chronic arthritis is known to exist even in paucibacillary forms, resolved or treated disease and in patients without reaction, suggesting a perpetuated inflammatory process. In these cases leprosy can mimic some autoimmune diseases such as rheumatoid arthritis. When a patient with a history of leprosy presents with a symmetric, distal, polyarthritis the diagnosis may not be linear. Possibly it is a rheumatoid-like leprous arthritis with M leprae acting as the trigger element for the chronic process or it is an overlap condition, with a concomitant rheumatoid arthritis? A case report of a patient with a chronic inflammatory arthritis with 10 years of evolution is presented. The differential diagnosis between leprous and rheumatoid arthritis is discussed.BMJ Publishing GroupRepositório do Centro Hospitalar Universitário de Lisboa Central, EPECoelho Henriques, CLopéz, BMestre, TGrima, BPanarra, ARiso, N2018-05-23T10:53:16Z2012-08-132012-08-13T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/2986engBMJ Case Rep. 2012 Aug 13;2012. pii: bcr1220115346.10.1136/bcr.12.2011.5346info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:40:40ZPortal AgregadorONG
dc.title.none.fl_str_mv Leprosy and Rheumatoid Arthritis: Consequence or Association?
title Leprosy and Rheumatoid Arthritis: Consequence or Association?
spellingShingle Leprosy and Rheumatoid Arthritis: Consequence or Association?
Coelho Henriques, C
Antirheumatic Agents
Arthritis, Infectious
Arthritis, Rheumatoid
Diagnosis, Differential
Female
Humans
Leprostatic Agents
Leprosy
Middle Aged
HCC MED
HCC DER
title_short Leprosy and Rheumatoid Arthritis: Consequence or Association?
title_full Leprosy and Rheumatoid Arthritis: Consequence or Association?
title_fullStr Leprosy and Rheumatoid Arthritis: Consequence or Association?
title_full_unstemmed Leprosy and Rheumatoid Arthritis: Consequence or Association?
title_sort Leprosy and Rheumatoid Arthritis: Consequence or Association?
author Coelho Henriques, C
author_facet Coelho Henriques, C
Lopéz, B
Mestre, T
Grima, B
Panarra, A
Riso, N
author_role author
author2 Lopéz, B
Mestre, T
Grima, B
Panarra, A
Riso, N
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE
dc.contributor.author.fl_str_mv Coelho Henriques, C
Lopéz, B
Mestre, T
Grima, B
Panarra, A
Riso, N
dc.subject.por.fl_str_mv Antirheumatic Agents
Arthritis, Infectious
Arthritis, Rheumatoid
Diagnosis, Differential
Female
Humans
Leprostatic Agents
Leprosy
Middle Aged
HCC MED
HCC DER
topic Antirheumatic Agents
Arthritis, Infectious
Arthritis, Rheumatoid
Diagnosis, Differential
Female
Humans
Leprostatic Agents
Leprosy
Middle Aged
HCC MED
HCC DER
description Leprosy or Hansen's disease is a chronic granulomatous infectious disease caused by Mycobacterium leprae with a high prevalence in some developing countries however, it is rarely seen in non-endemic regions. Arthritis has been described in all types of Hansen's disease. Chronic arthritis is known to exist even in paucibacillary forms, resolved or treated disease and in patients without reaction, suggesting a perpetuated inflammatory process. In these cases leprosy can mimic some autoimmune diseases such as rheumatoid arthritis. When a patient with a history of leprosy presents with a symmetric, distal, polyarthritis the diagnosis may not be linear. Possibly it is a rheumatoid-like leprous arthritis with M leprae acting as the trigger element for the chronic process or it is an overlap condition, with a concomitant rheumatoid arthritis? A case report of a patient with a chronic inflammatory arthritis with 10 years of evolution is presented. The differential diagnosis between leprous and rheumatoid arthritis is discussed.
publishDate 2012
dc.date.none.fl_str_mv 2012-08-13
2012-08-13T00:00:00Z
2018-05-23T10:53:16Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.17/2986
url http://hdl.handle.net/10400.17/2986
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv BMJ Case Rep. 2012 Aug 13;2012. pii: bcr1220115346.
10.1136/bcr.12.2011.5346
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv BMJ Publishing Group
publisher.none.fl_str_mv BMJ Publishing Group
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv
repository.mail.fl_str_mv
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