Study of InDel genetic markers with forensic and ancestry informative interest in PALOP's immigrant populations in Lisboa

Detalhes bibliográficos
Autor(a) principal: Inácio, Ana
Data de Publicação: 2017
Outros Autores: Costa, Heloísa Afonso, Silva, Cláudia Vieira da, Ribeiro, Teresa, Porto, Maria João, Santos, Jorge Costa, Igrejas, Gilberto, Amorim, António
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.26/19475
Resumo: The migratory phenomenon in Portugal has become one of the main factors for the genetic variability. In the last few years, a new class of autosomal insertion/deletion markers—InDel—has attracted interest in forensic genetics. Since there is no data for InDel markers of Portuguese-speaking African countries (PALOP) immigrants living in Lisboa, our aim is the characterization of those groups of individuals by typing them with at least 30 InDel markers and to compare different groups of individuals/populations. We studied 454 bloodstain samples belonging to immigrant individuals from Angola, Guinea-Bissau, and Mozambique. DNA extraction was performed with the Chelex® 100 method. After extraction, all samples were typed with the Investigator® DIPplex method. Through the obtained results, allelic frequencies show that all markers are at Hardy-Weinberg equilibrium, and we can confirm that those populations show significant genetic distances between themselves, between them, and the host Lisboa population. Because of this, they introduce genetic variability in Lisboa population.
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spelling Study of InDel genetic markers with forensic and ancestry informative interest in PALOP's immigrant populations in LisboaPALOP immigrantsInDelLisboa populationThe migratory phenomenon in Portugal has become one of the main factors for the genetic variability. In the last few years, a new class of autosomal insertion/deletion markers—InDel—has attracted interest in forensic genetics. Since there is no data for InDel markers of Portuguese-speaking African countries (PALOP) immigrants living in Lisboa, our aim is the characterization of those groups of individuals by typing them with at least 30 InDel markers and to compare different groups of individuals/populations. We studied 454 bloodstain samples belonging to immigrant individuals from Angola, Guinea-Bissau, and Mozambique. DNA extraction was performed with the Chelex® 100 method. After extraction, all samples were typed with the Investigator® DIPplex method. Through the obtained results, allelic frequencies show that all markers are at Hardy-Weinberg equilibrium, and we can confirm that those populations show significant genetic distances between themselves, between them, and the host Lisboa population. Because of this, they introduce genetic variability in Lisboa population.SpringerRepositório ComumInácio, AnaCosta, Heloísa AfonsoSilva, Cláudia Vieira daRibeiro, TeresaPorto, Maria JoãoSantos, Jorge CostaIgrejas, GilbertoAmorim, António2017-11-22T15:30:09Z2017-05-01T00:00:00Z2017-05-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/19475engInácio, A., Costa, H.A., da Silva, C.V. et al. Int J Legal Med (2017) 131: 657. https://doi.org/10.1007/s00414-016-1484-30937-982710.1007/s00414-016-1484-3info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-10-06T14:53:02Zoai:comum.rcaap.pt:10400.26/19475Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:09:00.839945Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Study of InDel genetic markers with forensic and ancestry informative interest in PALOP's immigrant populations in Lisboa
title Study of InDel genetic markers with forensic and ancestry informative interest in PALOP's immigrant populations in Lisboa
spellingShingle Study of InDel genetic markers with forensic and ancestry informative interest in PALOP's immigrant populations in Lisboa
Inácio, Ana
PALOP immigrants
InDel
Lisboa population
title_short Study of InDel genetic markers with forensic and ancestry informative interest in PALOP's immigrant populations in Lisboa
title_full Study of InDel genetic markers with forensic and ancestry informative interest in PALOP's immigrant populations in Lisboa
title_fullStr Study of InDel genetic markers with forensic and ancestry informative interest in PALOP's immigrant populations in Lisboa
title_full_unstemmed Study of InDel genetic markers with forensic and ancestry informative interest in PALOP's immigrant populations in Lisboa
title_sort Study of InDel genetic markers with forensic and ancestry informative interest in PALOP's immigrant populations in Lisboa
author Inácio, Ana
author_facet Inácio, Ana
Costa, Heloísa Afonso
Silva, Cláudia Vieira da
Ribeiro, Teresa
Porto, Maria João
Santos, Jorge Costa
Igrejas, Gilberto
Amorim, António
author_role author
author2 Costa, Heloísa Afonso
Silva, Cláudia Vieira da
Ribeiro, Teresa
Porto, Maria João
Santos, Jorge Costa
Igrejas, Gilberto
Amorim, António
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Comum
dc.contributor.author.fl_str_mv Inácio, Ana
Costa, Heloísa Afonso
Silva, Cláudia Vieira da
Ribeiro, Teresa
Porto, Maria João
Santos, Jorge Costa
Igrejas, Gilberto
Amorim, António
dc.subject.por.fl_str_mv PALOP immigrants
InDel
Lisboa population
topic PALOP immigrants
InDel
Lisboa population
description The migratory phenomenon in Portugal has become one of the main factors for the genetic variability. In the last few years, a new class of autosomal insertion/deletion markers—InDel—has attracted interest in forensic genetics. Since there is no data for InDel markers of Portuguese-speaking African countries (PALOP) immigrants living in Lisboa, our aim is the characterization of those groups of individuals by typing them with at least 30 InDel markers and to compare different groups of individuals/populations. We studied 454 bloodstain samples belonging to immigrant individuals from Angola, Guinea-Bissau, and Mozambique. DNA extraction was performed with the Chelex® 100 method. After extraction, all samples were typed with the Investigator® DIPplex method. Through the obtained results, allelic frequencies show that all markers are at Hardy-Weinberg equilibrium, and we can confirm that those populations show significant genetic distances between themselves, between them, and the host Lisboa population. Because of this, they introduce genetic variability in Lisboa population.
publishDate 2017
dc.date.none.fl_str_mv 2017-11-22T15:30:09Z
2017-05-01T00:00:00Z
2017-05-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/19475
url http://hdl.handle.net/10400.26/19475
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Inácio, A., Costa, H.A., da Silva, C.V. et al. Int J Legal Med (2017) 131: 657. https://doi.org/10.1007/s00414-016-1484-3
0937-9827
10.1007/s00414-016-1484-3
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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