Characterization of education, technical practices and attitudes of Portuguese pharmacy technicians towards manipulation of cytotoxic drugs

• Autor(a) principal: Campos, Daniela
• Data de Publicação: 2023
• Outros Autores: Silva, Inês, Rego, Mariana, Correia, Patrícia, Moreira, Fernando
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: http://hdl.handle.net/10400.22/24920
• topic: Cytotoxic; Chemotherapy; Antineoplastic agents; Occupational exposure; Pharmacy technicians

Pharmacy professionals that manipulate cytotoxic drugs need to undergo educational programs, adopt the most convenient practices, and use appropriate equipment to avoid, as far as possible, occupational exposure to cytotoxic drugs. The main goal of this work is to characterize the education, technical practices, and attitudes towards cytotoxic drugs, of Portuguese pharmacy technicians. A questionnaire comprising eleven questions deemed pertinent was elaborated and subsequently validated by a pilot test. The anonymous, web-based survey was conducted between December 2022 and January 2023, by graduated pharmacy technicians that had manipulated cytotoxic drugs between 2017 and 2022. A total of 77 pharmacy technicians responded to the survey. Although sixty-six pharmacy technicians (86%) had been trained before beginning to manipulate cytotoxic drugs, the promotion of regular post-admission training by the institutions is sparse – only assumed by 53% of the pharmacy technicians (n=41). All participants reported using gloves and gown during manipulation and the use of double gloves was common (99%; n=76). Compliances with the recommended limit time for uninterrupted manipulation activity (82%; n=63) and systematic double-checking (86%; n=66) were high, but the regular use of sterile gauze around syringe connection sites 58% (n=45), was less frequent. None of the surveyed pharmacy technicians used closed-system transfer devices (CSTD) and 41 (53%) of those who used spikes did not thoughtfully use these devices. The implementation of regular training programs in manipulating cytotoxic drugs should be fostered, to promote the more judicious use of engineering controls and transversal adoption of the safest technical practices.