Adipose tissue insulin resistance and lipidome alterations as the characterizing factors of non-alcoholic steatohepatitis

Detalhes bibliográficos
Autor(a) principal: Guerra, Sara Isabel da Silva
Data de Publicação: 2022
Outros Autores: Mocciaro, Gabriele, Gastaldelli, Amalia
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10316/103991
https://doi.org/10.1111/eci.13695
Resumo: The prevalence of non-alcoholic fatty liver disease (NAFLD) is now 25% in the general population but increases to more than 55% in subjects with obesity and/or type 2 diabetes. Simple steatosis (NAFL) can develop into more severe forms, that is non-alcoholic steatohepatitis (NASH), cirrhosis and hepatocellular carcinoma leading to death.
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spelling Adipose tissue insulin resistance and lipidome alterations as the characterizing factors of non-alcoholic steatohepatitislipidomics; lipotoxicity; mitochondrial dysfunction; non-alcoholic fatty liver diseaseAdipose TissueHumansNon-alcoholic Fatty Liver DiseaseInsulin ResistanceLipidomicsThe prevalence of non-alcoholic fatty liver disease (NAFLD) is now 25% in the general population but increases to more than 55% in subjects with obesity and/or type 2 diabetes. Simple steatosis (NAFL) can develop into more severe forms, that is non-alcoholic steatohepatitis (NASH), cirrhosis and hepatocellular carcinoma leading to death.2022-03info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/103991http://hdl.handle.net/10316/103991https://doi.org/10.1111/eci.13695por0014-29721365-2362https://onlinelibrary.wiley.com/doi/10.1111/eci.13695Guerra, Sara Isabel da SilvaMocciaro, GabrieleGastaldelli, Amaliainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-12-14T21:38:42Zoai:estudogeral.uc.pt:10316/103991Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:20:43.724552Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Adipose tissue insulin resistance and lipidome alterations as the characterizing factors of non-alcoholic steatohepatitis
title Adipose tissue insulin resistance and lipidome alterations as the characterizing factors of non-alcoholic steatohepatitis
spellingShingle Adipose tissue insulin resistance and lipidome alterations as the characterizing factors of non-alcoholic steatohepatitis
Guerra, Sara Isabel da Silva
lipidomics; lipotoxicity; mitochondrial dysfunction; non-alcoholic fatty liver disease
Adipose Tissue
Humans
Non-alcoholic Fatty Liver Disease
Insulin Resistance
Lipidomics
title_short Adipose tissue insulin resistance and lipidome alterations as the characterizing factors of non-alcoholic steatohepatitis
title_full Adipose tissue insulin resistance and lipidome alterations as the characterizing factors of non-alcoholic steatohepatitis
title_fullStr Adipose tissue insulin resistance and lipidome alterations as the characterizing factors of non-alcoholic steatohepatitis
title_full_unstemmed Adipose tissue insulin resistance and lipidome alterations as the characterizing factors of non-alcoholic steatohepatitis
title_sort Adipose tissue insulin resistance and lipidome alterations as the characterizing factors of non-alcoholic steatohepatitis
author Guerra, Sara Isabel da Silva
author_facet Guerra, Sara Isabel da Silva
Mocciaro, Gabriele
Gastaldelli, Amalia
author_role author
author2 Mocciaro, Gabriele
Gastaldelli, Amalia
author2_role author
author
dc.contributor.author.fl_str_mv Guerra, Sara Isabel da Silva
Mocciaro, Gabriele
Gastaldelli, Amalia
dc.subject.por.fl_str_mv lipidomics; lipotoxicity; mitochondrial dysfunction; non-alcoholic fatty liver disease
Adipose Tissue
Humans
Non-alcoholic Fatty Liver Disease
Insulin Resistance
Lipidomics
topic lipidomics; lipotoxicity; mitochondrial dysfunction; non-alcoholic fatty liver disease
Adipose Tissue
Humans
Non-alcoholic Fatty Liver Disease
Insulin Resistance
Lipidomics
description The prevalence of non-alcoholic fatty liver disease (NAFLD) is now 25% in the general population but increases to more than 55% in subjects with obesity and/or type 2 diabetes. Simple steatosis (NAFL) can develop into more severe forms, that is non-alcoholic steatohepatitis (NASH), cirrhosis and hepatocellular carcinoma leading to death.
publishDate 2022
dc.date.none.fl_str_mv 2022-03
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10316/103991
http://hdl.handle.net/10316/103991
https://doi.org/10.1111/eci.13695
url http://hdl.handle.net/10316/103991
https://doi.org/10.1111/eci.13695
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv 0014-2972
1365-2362
https://onlinelibrary.wiley.com/doi/10.1111/eci.13695
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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