Plasmodium falciparum malaria, bilateral sixth cranial nerve palsy and delayed cerebellar ataxia

Detalhes bibliográficos
Autor(a) principal: Duque, V
Data de Publicação: 2012
Outros Autores: Seixas, D, Ventura, C, Saraiva da Cunha, JG, Meliço-Silvestre, A
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.4/1348
Resumo: We describe the case of a 14-year-old Caucasian male, a resident in the Democratic Republic of the Congo, who was observed in Portugal with severe Plasmodium falciparum malaria with high-level parasitemia and severe thrombocytopenia. The course was complicated by bilateral sixth cranial nerve palsy during acute malaria, followed by the appearance of delayed cerebellar ataxia during the recovery phase. This occurred after successful treatment with quinine plus doxycycline over seven days. Different levels of thrombocytopenia and C-reactive protein were observed during both neurologic events in the presence of HRP-2 positive tests for Plasmodium falciparum antigen. The patient recovered completely after three months.
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spelling Plasmodium falciparum malaria, bilateral sixth cranial nerve palsy and delayed cerebellar ataxiaAtaxia CerebelarMalaria CerebralWe describe the case of a 14-year-old Caucasian male, a resident in the Democratic Republic of the Congo, who was observed in Portugal with severe Plasmodium falciparum malaria with high-level parasitemia and severe thrombocytopenia. The course was complicated by bilateral sixth cranial nerve palsy during acute malaria, followed by the appearance of delayed cerebellar ataxia during the recovery phase. This occurred after successful treatment with quinine plus doxycycline over seven days. Different levels of thrombocytopenia and C-reactive protein were observed during both neurologic events in the presence of HRP-2 positive tests for Plasmodium falciparum antigen. The patient recovered completely after three months.RIHUCDuque, VSeixas, DVentura, CSaraiva da Cunha, JGMeliço-Silvestre, A2012-03-22T18:51:12Z20122012-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.4/1348engJ Infect Dev Ctries. 2012;6(3):290-4.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-11T14:22:37Zoai:rihuc.huc.min-saude.pt:10400.4/1348Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:03:52.673510Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Plasmodium falciparum malaria, bilateral sixth cranial nerve palsy and delayed cerebellar ataxia
title Plasmodium falciparum malaria, bilateral sixth cranial nerve palsy and delayed cerebellar ataxia
spellingShingle Plasmodium falciparum malaria, bilateral sixth cranial nerve palsy and delayed cerebellar ataxia
Duque, V
Ataxia Cerebelar
Malaria Cerebral
title_short Plasmodium falciparum malaria, bilateral sixth cranial nerve palsy and delayed cerebellar ataxia
title_full Plasmodium falciparum malaria, bilateral sixth cranial nerve palsy and delayed cerebellar ataxia
title_fullStr Plasmodium falciparum malaria, bilateral sixth cranial nerve palsy and delayed cerebellar ataxia
title_full_unstemmed Plasmodium falciparum malaria, bilateral sixth cranial nerve palsy and delayed cerebellar ataxia
title_sort Plasmodium falciparum malaria, bilateral sixth cranial nerve palsy and delayed cerebellar ataxia
author Duque, V
author_facet Duque, V
Seixas, D
Ventura, C
Saraiva da Cunha, JG
Meliço-Silvestre, A
author_role author
author2 Seixas, D
Ventura, C
Saraiva da Cunha, JG
Meliço-Silvestre, A
author2_role author
author
author
author
dc.contributor.none.fl_str_mv RIHUC
dc.contributor.author.fl_str_mv Duque, V
Seixas, D
Ventura, C
Saraiva da Cunha, JG
Meliço-Silvestre, A
dc.subject.por.fl_str_mv Ataxia Cerebelar
Malaria Cerebral
topic Ataxia Cerebelar
Malaria Cerebral
description We describe the case of a 14-year-old Caucasian male, a resident in the Democratic Republic of the Congo, who was observed in Portugal with severe Plasmodium falciparum malaria with high-level parasitemia and severe thrombocytopenia. The course was complicated by bilateral sixth cranial nerve palsy during acute malaria, followed by the appearance of delayed cerebellar ataxia during the recovery phase. This occurred after successful treatment with quinine plus doxycycline over seven days. Different levels of thrombocytopenia and C-reactive protein were observed during both neurologic events in the presence of HRP-2 positive tests for Plasmodium falciparum antigen. The patient recovered completely after three months.
publishDate 2012
dc.date.none.fl_str_mv 2012-03-22T18:51:12Z
2012
2012-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.4/1348
url http://hdl.handle.net/10400.4/1348
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv J Infect Dev Ctries. 2012;6(3):290-4.
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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