Essential role of small bowel capsule endoscopy in reclassification of colonic inflammatory bowel disease type unclassified
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/51536 |
Resumo: | AIM To evaluate the role of small bowel capsule endoscopy (SBCE) on the reclassification of colonic inflammatory bowel disease type unclassified (IBDU). METHODS We performed a multicenter, retrospective study including patients with IBDU undergoing SBCE, between 2002 and 2014. SBCE studies were reviewed and the inflammatory activity was evaluated by determining the Lewis score (LS). Inflammatory activity was considered significant and consistent with Crohn's disease (CD) when the LS >= 135. The definitive diagnosis during follow-up (minimum 12 mo following SBCE) was based on the combination of clinical, analytical, imaging, endoscopic and histological elements. RESULTS Thirty-six patients were included, 21 females (58%) with mean age at diagnosis of 33 +/- 13 (15-64) years. The mean follow-up time after the SBCE was 52 +/- 41 (12-156) mo. The SBCE revealed findings consistent with significant inflammatory activity in the small bowel (LS >= 135) in 9 patients (25%); in all of them the diagnosis of CD was confirmed during follow-up. In 27 patients (75%), the SBCE revealed no significant inflammatory activity (LS < 135); among these patients, the diagnosis of Ulcerative Colitis (UC) was established in 16 cases (59.3%), CD in 1 case (3.7%) and 10 patients (37%) maintained a diagnosis of IBDU during follow-up. A LS >= 135 at SBCE had a sensitivity = 90%, specificity = 100%, positive predictive value = 100% and negative predictive value = 94% for the diagnosis of CD. CONCLUSION SBCE proved to be fundamental in the reclassification of patients with IBDU. Absence of significant inflammatory activity in the small intestine allowed exclusion of CD in 94% of cases. |
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Essential role of small bowel capsule endoscopy in reclassification of colonic inflammatory bowel disease type unclassifiedInflammatory bowel diseaseInflammatory bowel disease type unclassifiedCapsule endoscopyCrohn's diseaseLewis scoreReclassificationCiências Médicas::Medicina ClínicaScience & TechnologyAIM To evaluate the role of small bowel capsule endoscopy (SBCE) on the reclassification of colonic inflammatory bowel disease type unclassified (IBDU). METHODS We performed a multicenter, retrospective study including patients with IBDU undergoing SBCE, between 2002 and 2014. SBCE studies were reviewed and the inflammatory activity was evaluated by determining the Lewis score (LS). Inflammatory activity was considered significant and consistent with Crohn's disease (CD) when the LS >= 135. The definitive diagnosis during follow-up (minimum 12 mo following SBCE) was based on the combination of clinical, analytical, imaging, endoscopic and histological elements. RESULTS Thirty-six patients were included, 21 females (58%) with mean age at diagnosis of 33 +/- 13 (15-64) years. The mean follow-up time after the SBCE was 52 +/- 41 (12-156) mo. The SBCE revealed findings consistent with significant inflammatory activity in the small bowel (LS >= 135) in 9 patients (25%); in all of them the diagnosis of CD was confirmed during follow-up. In 27 patients (75%), the SBCE revealed no significant inflammatory activity (LS < 135); among these patients, the diagnosis of Ulcerative Colitis (UC) was established in 16 cases (59.3%), CD in 1 case (3.7%) and 10 patients (37%) maintained a diagnosis of IBDU during follow-up. A LS >= 135 at SBCE had a sensitivity = 90%, specificity = 100%, positive predictive value = 100% and negative predictive value = 94% for the diagnosis of CD. CONCLUSION SBCE proved to be fundamental in the reclassification of patients with IBDU. Absence of significant inflammatory activity in the small intestine allowed exclusion of CD in 94% of cases.info:eu-repo/semantics/publishedVersionBaishideng Publishing GroupUniversidade do MinhoMonteiro, SaraCastro, Francisca Dias deCarvalho, Pedro BoalRosa, BrunoMoreira, Maria JoãoPinho, RolandoSaraiva, Miguel MascarenhasCotter, José Almeida Berkeley2017-01-022017-01-02T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/51536engMonteiro, S., de Castro, F. D., Carvalho, P. B., Rosa, B., Moreira, M. J., Pinho, R., ... & Cotter, J. (2017). Essential role of small bowel capsule endoscopy in reclassification of colonic inflammatory bowel disease type unclassified. World journal of gastrointestinal endoscopy, 9(1), 34.1948-519010.4253/wjge.v9.i1.34https://www.wjgnet.com/1948-5190/full/v9/i1/34.htminfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:19:23Zoai:repositorium.sdum.uminho.pt:1822/51536Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:12:18.921657Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Essential role of small bowel capsule endoscopy in reclassification of colonic inflammatory bowel disease type unclassified |
title |
Essential role of small bowel capsule endoscopy in reclassification of colonic inflammatory bowel disease type unclassified |
spellingShingle |
Essential role of small bowel capsule endoscopy in reclassification of colonic inflammatory bowel disease type unclassified Monteiro, Sara Inflammatory bowel disease Inflammatory bowel disease type unclassified Capsule endoscopy Crohn's disease Lewis score Reclassification Ciências Médicas::Medicina Clínica Science & Technology |
title_short |
Essential role of small bowel capsule endoscopy in reclassification of colonic inflammatory bowel disease type unclassified |
title_full |
Essential role of small bowel capsule endoscopy in reclassification of colonic inflammatory bowel disease type unclassified |
title_fullStr |
Essential role of small bowel capsule endoscopy in reclassification of colonic inflammatory bowel disease type unclassified |
title_full_unstemmed |
Essential role of small bowel capsule endoscopy in reclassification of colonic inflammatory bowel disease type unclassified |
title_sort |
Essential role of small bowel capsule endoscopy in reclassification of colonic inflammatory bowel disease type unclassified |
author |
Monteiro, Sara |
author_facet |
Monteiro, Sara Castro, Francisca Dias de Carvalho, Pedro Boal Rosa, Bruno Moreira, Maria João Pinho, Rolando Saraiva, Miguel Mascarenhas Cotter, José Almeida Berkeley |
author_role |
author |
author2 |
Castro, Francisca Dias de Carvalho, Pedro Boal Rosa, Bruno Moreira, Maria João Pinho, Rolando Saraiva, Miguel Mascarenhas Cotter, José Almeida Berkeley |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Monteiro, Sara Castro, Francisca Dias de Carvalho, Pedro Boal Rosa, Bruno Moreira, Maria João Pinho, Rolando Saraiva, Miguel Mascarenhas Cotter, José Almeida Berkeley |
dc.subject.por.fl_str_mv |
Inflammatory bowel disease Inflammatory bowel disease type unclassified Capsule endoscopy Crohn's disease Lewis score Reclassification Ciências Médicas::Medicina Clínica Science & Technology |
topic |
Inflammatory bowel disease Inflammatory bowel disease type unclassified Capsule endoscopy Crohn's disease Lewis score Reclassification Ciências Médicas::Medicina Clínica Science & Technology |
description |
AIM To evaluate the role of small bowel capsule endoscopy (SBCE) on the reclassification of colonic inflammatory bowel disease type unclassified (IBDU). METHODS We performed a multicenter, retrospective study including patients with IBDU undergoing SBCE, between 2002 and 2014. SBCE studies were reviewed and the inflammatory activity was evaluated by determining the Lewis score (LS). Inflammatory activity was considered significant and consistent with Crohn's disease (CD) when the LS >= 135. The definitive diagnosis during follow-up (minimum 12 mo following SBCE) was based on the combination of clinical, analytical, imaging, endoscopic and histological elements. RESULTS Thirty-six patients were included, 21 females (58%) with mean age at diagnosis of 33 +/- 13 (15-64) years. The mean follow-up time after the SBCE was 52 +/- 41 (12-156) mo. The SBCE revealed findings consistent with significant inflammatory activity in the small bowel (LS >= 135) in 9 patients (25%); in all of them the diagnosis of CD was confirmed during follow-up. In 27 patients (75%), the SBCE revealed no significant inflammatory activity (LS < 135); among these patients, the diagnosis of Ulcerative Colitis (UC) was established in 16 cases (59.3%), CD in 1 case (3.7%) and 10 patients (37%) maintained a diagnosis of IBDU during follow-up. A LS >= 135 at SBCE had a sensitivity = 90%, specificity = 100%, positive predictive value = 100% and negative predictive value = 94% for the diagnosis of CD. CONCLUSION SBCE proved to be fundamental in the reclassification of patients with IBDU. Absence of significant inflammatory activity in the small intestine allowed exclusion of CD in 94% of cases. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-01-02 2017-01-02T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/51536 |
url |
http://hdl.handle.net/1822/51536 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Monteiro, S., de Castro, F. D., Carvalho, P. B., Rosa, B., Moreira, M. J., Pinho, R., ... & Cotter, J. (2017). Essential role of small bowel capsule endoscopy in reclassification of colonic inflammatory bowel disease type unclassified. World journal of gastrointestinal endoscopy, 9(1), 34. 1948-5190 10.4253/wjge.v9.i1.34 https://www.wjgnet.com/1948-5190/full/v9/i1/34.htm |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Baishideng Publishing Group |
publisher.none.fl_str_mv |
Baishideng Publishing Group |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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