Severe Imported Malaria in Critical Care Patients
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/285 |
Resumo: | Introduction: Imported malaria is a frequent diagnosis in Portugal, and in the most severe clinical forms it may present a high mortality rate. Material and Methods: We present seven cases of severe imported malaria, admitted to an intensive care unit between 2000 and 2010, with particular focus on risk factors, clinical presentation, treatment and results. Results: All patients had a history of recent travel to African endemic areas for malaria. Plasmodium falciparum was the agent isolated in all cases. Most patients had an inadequate prophylaxis. High parasitaemia in non-immune patients and treatment delay were associated with more severe clinical presentation. All the cases were complicated by organ failure, and three patients needed organ support and in two exchange blood transfusions were performed. There was one single death that was associated with marked delay in the initiation of therapy. Conclusion: In these patients, early and aggressive treatment, with a organ support in a critical care setting, allowed a good outcome with low mortality and no significant sequelae, despite the severity of presentation. |
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Severe Imported Malaria in Critical Care PatientsMalária Grave Importada em Doentes CríticosIntroduction: Imported malaria is a frequent diagnosis in Portugal, and in the most severe clinical forms it may present a high mortality rate. Material and Methods: We present seven cases of severe imported malaria, admitted to an intensive care unit between 2000 and 2010, with particular focus on risk factors, clinical presentation, treatment and results. Results: All patients had a history of recent travel to African endemic areas for malaria. Plasmodium falciparum was the agent isolated in all cases. Most patients had an inadequate prophylaxis. High parasitaemia in non-immune patients and treatment delay were associated with more severe clinical presentation. All the cases were complicated by organ failure, and three patients needed organ support and in two exchange blood transfusions were performed. There was one single death that was associated with marked delay in the initiation of therapy. Conclusion: In these patients, early and aggressive treatment, with a organ support in a critical care setting, allowed a good outcome with low mortality and no significant sequelae, despite the severity of presentation.Introdução: A malária importada é um diagnóstico frequente em Portugal, podendo apresentar nas suas formas mais graves, elevada mortalidade.Material e Métodos: Apresentam-se sete casos de malária grave importada, admitidos numa unidade de cuidados intensivos entre 2000 e 2010, com especial enfoque nos factores de risco, apresentação clínica, terapêutica e resultados.Resultados: Todos os doentes tinham história de viagens recentes a zonas africanas endémicas para malária. O agente isolado foi sempre o Plasmodium falciparum. A maioria dos doentes não fez profilaxia adequada. A parasitémia elevada em doentes não imunes e o atraso no início do tratamento associaram-se a quadros clínicos mais graves. Todos estes casos de malária foram complicados por falência orgânica intercorrente, sendo que três dos doentes tiveram de ser submetidos a técnicas de suporte de órgão e dois a exsanguíneo-transfusões. Verificou-se um óbito, associado ao atraso no início da terapêutica.Conclusão: Nestes doentes o tratamento precoce e agressivo, com suporte dos órgãos em falência, em cuidados intensivos, permitiu uma boa evolução, com baixa mortalidade e ausência de sequelas significativas, apesar da gravidade de apresentação.Ordem dos Médicos2012-11-12info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/x-pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/285oai:ojs.www.actamedicaportuguesa.com:article/285Acta Médica Portuguesa; Vol. 25 No. 5 (2012): September-October; 271-276Acta Médica Portuguesa; Vol. 25 N.º 5 (2012): Setembro-Outubro; 271-2761646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/285https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/285/80Direitos de Autor (c) 2012 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessPalma dos Reis, InêsSerafim, CatarinaValério, BernardinoAraújo, RobsonSilvestre, JoanaMendes, VítorTapadinhas, CamilaGonçalves Pereira, JoãoPóvoa, Pedro2022-12-20T10:55:58Zoai:ojs.www.actamedicaportuguesa.com:article/285Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:16:25.225780Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Severe Imported Malaria in Critical Care Patients Malária Grave Importada em Doentes Críticos |
title |
Severe Imported Malaria in Critical Care Patients |
spellingShingle |
Severe Imported Malaria in Critical Care Patients Palma dos Reis, Inês |
title_short |
Severe Imported Malaria in Critical Care Patients |
title_full |
Severe Imported Malaria in Critical Care Patients |
title_fullStr |
Severe Imported Malaria in Critical Care Patients |
title_full_unstemmed |
Severe Imported Malaria in Critical Care Patients |
title_sort |
Severe Imported Malaria in Critical Care Patients |
author |
Palma dos Reis, Inês |
author_facet |
Palma dos Reis, Inês Serafim, Catarina Valério, Bernardino Araújo, Robson Silvestre, Joana Mendes, Vítor Tapadinhas, Camila Gonçalves Pereira, João Póvoa, Pedro |
author_role |
author |
author2 |
Serafim, Catarina Valério, Bernardino Araújo, Robson Silvestre, Joana Mendes, Vítor Tapadinhas, Camila Gonçalves Pereira, João Póvoa, Pedro |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Palma dos Reis, Inês Serafim, Catarina Valério, Bernardino Araújo, Robson Silvestre, Joana Mendes, Vítor Tapadinhas, Camila Gonçalves Pereira, João Póvoa, Pedro |
description |
Introduction: Imported malaria is a frequent diagnosis in Portugal, and in the most severe clinical forms it may present a high mortality rate. Material and Methods: We present seven cases of severe imported malaria, admitted to an intensive care unit between 2000 and 2010, with particular focus on risk factors, clinical presentation, treatment and results. Results: All patients had a history of recent travel to African endemic areas for malaria. Plasmodium falciparum was the agent isolated in all cases. Most patients had an inadequate prophylaxis. High parasitaemia in non-immune patients and treatment delay were associated with more severe clinical presentation. All the cases were complicated by organ failure, and three patients needed organ support and in two exchange blood transfusions were performed. There was one single death that was associated with marked delay in the initiation of therapy. Conclusion: In these patients, early and aggressive treatment, with a organ support in a critical care setting, allowed a good outcome with low mortality and no significant sequelae, despite the severity of presentation. |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-11-12 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/285 oai:ojs.www.actamedicaportuguesa.com:article/285 |
url |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/285 |
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oai:ojs.www.actamedicaportuguesa.com:article/285 |
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por |
language |
por |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/285 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/285/80 |
dc.rights.driver.fl_str_mv |
Direitos de Autor (c) 2012 Acta Médica Portuguesa info:eu-repo/semantics/openAccess |
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Direitos de Autor (c) 2012 Acta Médica Portuguesa |
eu_rights_str_mv |
openAccess |
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application/x-pdf |
dc.publisher.none.fl_str_mv |
Ordem dos Médicos |
publisher.none.fl_str_mv |
Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 25 No. 5 (2012): September-October; 271-276 Acta Médica Portuguesa; Vol. 25 N.º 5 (2012): Setembro-Outubro; 271-276 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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