Structural equation modelling for predicting the relative contribution of each component in the metabolic syndrome status change
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10198/25342 |
Resumo: | Understanding the factor weighting in the development of metabolic syndrome (MetS) may help to predict the progression for cardiovascular and metabolic diseases. Thus, the aim of this study was to develop a confirmatory model to describe and explain the direct and indirect effect of each component in MetS status change. A total of 3581 individuals diagnosed with MetS, aged 18–102 years, were selected between January 2019 and December 2020 from a community-representative sample of Portuguese adults in a north-eastern Portuguese region to test the model’s goodness of fit. A structural equation modelling (SEM) approach and a two-way ANOVA (age × body composition) were performed to compare the relative contribution of each MetS component using joint interim statement (JIS). Waist circumference (β = 0.189–0.373, p < 0.001), fasting glucose (β = 0.168–0.199, p < 0.001) and systolic blood pressure (β = 0.140–0.162, p < 0.001) had the highest direct effect on the change in MetS status in the overall population and concerning both sexes. Moreover, diastolic blood pressure (DBP), triglycerides (TG) and high-density lipoprotein cholesterol (HDL-c) had a low or non-significant effect. Additionally, an indirect effect was reported for age and body composition involving the change in MetS status. The findings may suggest that other components with higher specificity and sensitivity should be considered to empirically validate the harmonised definition of MetS. Current research provides the first multivariate model for predicting the relative contribution of each component in the MetS status change, specifically in Portuguese adults. |
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Structural equation modelling for predicting the relative contribution of each component in the metabolic syndrome status changeMetabolic syndromeMultilevel modellingPredictionProgressionPublic healthUnderstanding the factor weighting in the development of metabolic syndrome (MetS) may help to predict the progression for cardiovascular and metabolic diseases. Thus, the aim of this study was to develop a confirmatory model to describe and explain the direct and indirect effect of each component in MetS status change. A total of 3581 individuals diagnosed with MetS, aged 18–102 years, were selected between January 2019 and December 2020 from a community-representative sample of Portuguese adults in a north-eastern Portuguese region to test the model’s goodness of fit. A structural equation modelling (SEM) approach and a two-way ANOVA (age × body composition) were performed to compare the relative contribution of each MetS component using joint interim statement (JIS). Waist circumference (β = 0.189–0.373, p < 0.001), fasting glucose (β = 0.168–0.199, p < 0.001) and systolic blood pressure (β = 0.140–0.162, p < 0.001) had the highest direct effect on the change in MetS status in the overall population and concerning both sexes. Moreover, diastolic blood pressure (DBP), triglycerides (TG) and high-density lipoprotein cholesterol (HDL-c) had a low or non-significant effect. Additionally, an indirect effect was reported for age and body composition involving the change in MetS status. The findings may suggest that other components with higher specificity and sensitivity should be considered to empirically validate the harmonised definition of MetS. Current research provides the first multivariate model for predicting the relative contribution of each component in the MetS status change, specifically in Portuguese adults.This article is a result of the project “GreenHealth-Digital strategies in biological assets to improve well-being and promote green health” (Norte-01-0145-FEDER-000042), supported by North Portugal Regional Operational Programme (NORTE 2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF). The authors also express acknowledgement all medical staff, patients and human resources of the two primary health care centers.MDPIBiblioteca Digital do IPBTeixeira, José EduardoBragada, José A.Bragada, João P.Coelho, JoanaPinto, IsabelReis, Luís P.Fernandes, Paula OdeteMorais, J.E.Magalhães, Pedro2022-04-05T09:08:24Z20222022-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/25342engTeixeira, J.E.; Bragada, José A.; Bragada, João P.; Coelho, Joana; Pinto, Isabel; Reis, Luís P.; Fernandes, Paula O.; Morais, J.E.; Magalhães, Pedro (2022). Structural equation modelling for predicting the relative contribution of each component in the metabolic syndrome status change. International Journal of Environmental Research and Public Health. ISSN 1660-4601. 19:6, p. 1-141660-460110.3390/ijerph19063384info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:56:27Zoai:bibliotecadigital.ipb.pt:10198/25342Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:15:54.952825Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Structural equation modelling for predicting the relative contribution of each component in the metabolic syndrome status change |
title |
Structural equation modelling for predicting the relative contribution of each component in the metabolic syndrome status change |
spellingShingle |
Structural equation modelling for predicting the relative contribution of each component in the metabolic syndrome status change Teixeira, José Eduardo Metabolic syndrome Multilevel modelling Prediction Progression Public health |
title_short |
Structural equation modelling for predicting the relative contribution of each component in the metabolic syndrome status change |
title_full |
Structural equation modelling for predicting the relative contribution of each component in the metabolic syndrome status change |
title_fullStr |
Structural equation modelling for predicting the relative contribution of each component in the metabolic syndrome status change |
title_full_unstemmed |
Structural equation modelling for predicting the relative contribution of each component in the metabolic syndrome status change |
title_sort |
Structural equation modelling for predicting the relative contribution of each component in the metabolic syndrome status change |
author |
Teixeira, José Eduardo |
author_facet |
Teixeira, José Eduardo Bragada, José A. Bragada, João P. Coelho, Joana Pinto, Isabel Reis, Luís P. Fernandes, Paula Odete Morais, J.E. Magalhães, Pedro |
author_role |
author |
author2 |
Bragada, José A. Bragada, João P. Coelho, Joana Pinto, Isabel Reis, Luís P. Fernandes, Paula Odete Morais, J.E. Magalhães, Pedro |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Biblioteca Digital do IPB |
dc.contributor.author.fl_str_mv |
Teixeira, José Eduardo Bragada, José A. Bragada, João P. Coelho, Joana Pinto, Isabel Reis, Luís P. Fernandes, Paula Odete Morais, J.E. Magalhães, Pedro |
dc.subject.por.fl_str_mv |
Metabolic syndrome Multilevel modelling Prediction Progression Public health |
topic |
Metabolic syndrome Multilevel modelling Prediction Progression Public health |
description |
Understanding the factor weighting in the development of metabolic syndrome (MetS) may help to predict the progression for cardiovascular and metabolic diseases. Thus, the aim of this study was to develop a confirmatory model to describe and explain the direct and indirect effect of each component in MetS status change. A total of 3581 individuals diagnosed with MetS, aged 18–102 years, were selected between January 2019 and December 2020 from a community-representative sample of Portuguese adults in a north-eastern Portuguese region to test the model’s goodness of fit. A structural equation modelling (SEM) approach and a two-way ANOVA (age × body composition) were performed to compare the relative contribution of each MetS component using joint interim statement (JIS). Waist circumference (β = 0.189–0.373, p < 0.001), fasting glucose (β = 0.168–0.199, p < 0.001) and systolic blood pressure (β = 0.140–0.162, p < 0.001) had the highest direct effect on the change in MetS status in the overall population and concerning both sexes. Moreover, diastolic blood pressure (DBP), triglycerides (TG) and high-density lipoprotein cholesterol (HDL-c) had a low or non-significant effect. Additionally, an indirect effect was reported for age and body composition involving the change in MetS status. The findings may suggest that other components with higher specificity and sensitivity should be considered to empirically validate the harmonised definition of MetS. Current research provides the first multivariate model for predicting the relative contribution of each component in the MetS status change, specifically in Portuguese adults. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-04-05T09:08:24Z 2022 2022-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10198/25342 |
url |
http://hdl.handle.net/10198/25342 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Teixeira, J.E.; Bragada, José A.; Bragada, João P.; Coelho, Joana; Pinto, Isabel; Reis, Luís P.; Fernandes, Paula O.; Morais, J.E.; Magalhães, Pedro (2022). Structural equation modelling for predicting the relative contribution of each component in the metabolic syndrome status change. International Journal of Environmental Research and Public Health. ISSN 1660-4601. 19:6, p. 1-14 1660-4601 10.3390/ijerph19063384 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
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application/pdf |
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MDPI |
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MDPI |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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