Fabrication of quasi-2D shape-tailored microparticles using wettability contrast-based platforms
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10773/34374 |
Resumo: | The ability to fabricate materials with ultrathin architectures enables the breakthrough of low-dimensional structures with high surface area that showcase distinctive properties from their bulk counterparts. They are exploited in a wide range of fields, including energy harvesting, catalysis, and biomedicine. Despite such versatility, the fine tuning of the lateral dimensions and geometry of these structures remains challenging. Prepatterned platforms gain significant attention as enabling technologies to process materials with highly controlled shapes and dimensions. Herein, different nanometer-thick particles of various lateral sizes and geometries (e.g., squares, circles, triangles, hexagons) are processed with high precision and definition, taking advantage of the wettability contrast of oleophilic-oleophobic patterned surfaces. Quasi-2D polymeric microparticles with high shape- and size-fidelity can be retrieved as freestanding objects in a single step. These structures show cell-mediated pliability, and their integration in gravity-enforced human adipose-derived stem cell spheroids leads to an enhanced metabolic activity and a modulated secretion of proangiogenic factors. |
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Fabrication of quasi-2D shape-tailored microparticles using wettability contrast-based platformsBioinspired surfacesOleophobic patterned surfacesQuasi-2D nanostructuresUltrathin microparticlesWettable–dewettable contrastThe ability to fabricate materials with ultrathin architectures enables the breakthrough of low-dimensional structures with high surface area that showcase distinctive properties from their bulk counterparts. They are exploited in a wide range of fields, including energy harvesting, catalysis, and biomedicine. Despite such versatility, the fine tuning of the lateral dimensions and geometry of these structures remains challenging. Prepatterned platforms gain significant attention as enabling technologies to process materials with highly controlled shapes and dimensions. Herein, different nanometer-thick particles of various lateral sizes and geometries (e.g., squares, circles, triangles, hexagons) are processed with high precision and definition, taking advantage of the wettability contrast of oleophilic-oleophobic patterned surfaces. Quasi-2D polymeric microparticles with high shape- and size-fidelity can be retrieved as freestanding objects in a single step. These structures show cell-mediated pliability, and their integration in gravity-enforced human adipose-derived stem cell spheroids leads to an enhanced metabolic activity and a modulated secretion of proangiogenic factors.Wiley2022-08-02T17:43:51Z2021-04-08T00:00:00Z2021-04-08info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10773/34374eng0935-964810.1002/adma.202007695Neto, Mafalda D.Stoppa, AukhaNeto, Miguel A.Oliveira, Filipe J.Gomes, Maria C.Boccaccini, Aldo R.Levkin, Pavel A.Oliveira, Mariana B.Mano, João F.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-22T12:06:25Zoai:ria.ua.pt:10773/34374Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:05:44.221206Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Fabrication of quasi-2D shape-tailored microparticles using wettability contrast-based platforms |
title |
Fabrication of quasi-2D shape-tailored microparticles using wettability contrast-based platforms |
spellingShingle |
Fabrication of quasi-2D shape-tailored microparticles using wettability contrast-based platforms Neto, Mafalda D. Bioinspired surfaces Oleophobic patterned surfaces Quasi-2D nanostructures Ultrathin microparticles Wettable–dewettable contrast |
title_short |
Fabrication of quasi-2D shape-tailored microparticles using wettability contrast-based platforms |
title_full |
Fabrication of quasi-2D shape-tailored microparticles using wettability contrast-based platforms |
title_fullStr |
Fabrication of quasi-2D shape-tailored microparticles using wettability contrast-based platforms |
title_full_unstemmed |
Fabrication of quasi-2D shape-tailored microparticles using wettability contrast-based platforms |
title_sort |
Fabrication of quasi-2D shape-tailored microparticles using wettability contrast-based platforms |
author |
Neto, Mafalda D. |
author_facet |
Neto, Mafalda D. Stoppa, Aukha Neto, Miguel A. Oliveira, Filipe J. Gomes, Maria C. Boccaccini, Aldo R. Levkin, Pavel A. Oliveira, Mariana B. Mano, João F. |
author_role |
author |
author2 |
Stoppa, Aukha Neto, Miguel A. Oliveira, Filipe J. Gomes, Maria C. Boccaccini, Aldo R. Levkin, Pavel A. Oliveira, Mariana B. Mano, João F. |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Neto, Mafalda D. Stoppa, Aukha Neto, Miguel A. Oliveira, Filipe J. Gomes, Maria C. Boccaccini, Aldo R. Levkin, Pavel A. Oliveira, Mariana B. Mano, João F. |
dc.subject.por.fl_str_mv |
Bioinspired surfaces Oleophobic patterned surfaces Quasi-2D nanostructures Ultrathin microparticles Wettable–dewettable contrast |
topic |
Bioinspired surfaces Oleophobic patterned surfaces Quasi-2D nanostructures Ultrathin microparticles Wettable–dewettable contrast |
description |
The ability to fabricate materials with ultrathin architectures enables the breakthrough of low-dimensional structures with high surface area that showcase distinctive properties from their bulk counterparts. They are exploited in a wide range of fields, including energy harvesting, catalysis, and biomedicine. Despite such versatility, the fine tuning of the lateral dimensions and geometry of these structures remains challenging. Prepatterned platforms gain significant attention as enabling technologies to process materials with highly controlled shapes and dimensions. Herein, different nanometer-thick particles of various lateral sizes and geometries (e.g., squares, circles, triangles, hexagons) are processed with high precision and definition, taking advantage of the wettability contrast of oleophilic-oleophobic patterned surfaces. Quasi-2D polymeric microparticles with high shape- and size-fidelity can be retrieved as freestanding objects in a single step. These structures show cell-mediated pliability, and their integration in gravity-enforced human adipose-derived stem cell spheroids leads to an enhanced metabolic activity and a modulated secretion of proangiogenic factors. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-04-08T00:00:00Z 2021-04-08 2022-08-02T17:43:51Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10773/34374 |
url |
http://hdl.handle.net/10773/34374 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
0935-9648 10.1002/adma.202007695 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Wiley |
publisher.none.fl_str_mv |
Wiley |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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