Sex differences in functional connectivity between resting state brain networks in Autism Spectrum Disorder

Detalhes bibliográficos
Autor(a) principal: Tavares, Vânia
Data de Publicação: 2021
Outros Autores: Fernandes, Luís Afonso, Antunes, Marilia, Ferreira, Hugo, Prata, Diana
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10451/49630
Resumo: © The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
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spelling Sex differences in functional connectivity between resting state brain networks in Autism Spectrum DisorderAutism spectrum disorderFunctional connectivityFunctional magnetic resonance imagingIndependent component analysisResting-state networks© The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.Functional brain connectivity (FBC) has previously been examined in autism spectrum disorder (ASD) between-resting-state networks (RSNs) using a highly sensitive and reproducible hypothesis-free approach. However, results have been inconsistent and sex differences have only recently been taken into consideration using this approach. We estimated main effects of diagnosis and sex and a diagnosis by sex interaction on between-RSNs FBC in 83 ASD (40 females/43 males) and 85 typically developing controls (TC; 43 females/42 males). We found increased connectivity between the default mode (DM) and (a) the executive control networks in ASD (vs. TC); (b) the cerebellum networks in males (vs. females); and (c) female-specific altered connectivity involving visual, language and basal ganglia (BG) networks in ASD-in suggestive compatibility with ASD cognitive and neuroscientific theories.VT received support from Fundação Ciência e Tecnologia (FCT) PhD fellowship (PD/BD/114460/2016) and paid by FCT DSAIPA/DS/0065/2018 Grant. DP was supported by the European Commission Seventh Framework Programme Marie Curie Career Integration Grant FP7-PEOPLE-2013-CIG-631952, the 2016 Bial Foundation Psychophysiology Grant Ref. 292/16, and the IF/00787/2014, LISBOA-01-0145-FEDER-030907 and DSAIPA/DS/0065/2018 FCT Grants, and the iMM Lisboa Director’s Fund Breakthrough Idea Grant 2016; and is co-founder and shareholder of the neuroimaging research services company NeuroPsyAI, Ltd. MA was supported by FCT Grant UID/MAT/00006/2013.Springer NatureRepositório da Universidade de LisboaTavares, VâniaFernandes, Luís AfonsoAntunes, MariliaFerreira, HugoPrata, Diana2021-09-24T17:41:23Z20212021-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/49630engJ Autism Dev Disord. 2021 Jul 160162-325710.1007/s10803-021-05191-61573-3432info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T16:53:34Zoai:repositorio.ul.pt:10451/49630Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:01:16.591400Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Sex differences in functional connectivity between resting state brain networks in Autism Spectrum Disorder
title Sex differences in functional connectivity between resting state brain networks in Autism Spectrum Disorder
spellingShingle Sex differences in functional connectivity between resting state brain networks in Autism Spectrum Disorder
Tavares, Vânia
Autism spectrum disorder
Functional connectivity
Functional magnetic resonance imaging
Independent component analysis
Resting-state networks
title_short Sex differences in functional connectivity between resting state brain networks in Autism Spectrum Disorder
title_full Sex differences in functional connectivity between resting state brain networks in Autism Spectrum Disorder
title_fullStr Sex differences in functional connectivity between resting state brain networks in Autism Spectrum Disorder
title_full_unstemmed Sex differences in functional connectivity between resting state brain networks in Autism Spectrum Disorder
title_sort Sex differences in functional connectivity between resting state brain networks in Autism Spectrum Disorder
author Tavares, Vânia
author_facet Tavares, Vânia
Fernandes, Luís Afonso
Antunes, Marilia
Ferreira, Hugo
Prata, Diana
author_role author
author2 Fernandes, Luís Afonso
Antunes, Marilia
Ferreira, Hugo
Prata, Diana
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade de Lisboa
dc.contributor.author.fl_str_mv Tavares, Vânia
Fernandes, Luís Afonso
Antunes, Marilia
Ferreira, Hugo
Prata, Diana
dc.subject.por.fl_str_mv Autism spectrum disorder
Functional connectivity
Functional magnetic resonance imaging
Independent component analysis
Resting-state networks
topic Autism spectrum disorder
Functional connectivity
Functional magnetic resonance imaging
Independent component analysis
Resting-state networks
description © The Author(s) 2021. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
publishDate 2021
dc.date.none.fl_str_mv 2021-09-24T17:41:23Z
2021
2021-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10451/49630
url http://hdl.handle.net/10451/49630
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv J Autism Dev Disord. 2021 Jul 16
0162-3257
10.1007/s10803-021-05191-6
1573-3432
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer Nature
publisher.none.fl_str_mv Springer Nature
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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