Isolation of terpenic compounds from the methanolic extract of Euphorbia lagascae. Screening of their in vitro activity against Mycobacterium tuberculosis and Staphylococcus aureus
Autor(a) principal: | |
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Data de Publicação: | 2005 |
Outros Autores: | , , , , , |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10884/473 |
Resumo: | For as long as man can remember, plants have been used worldwide for the treatment of diseases. Today, many of the drugs currently used are derived from natural products or have dependent upon a natural product for their development and the recent discoveries of the antimalarial artemisinin and the anticancer agent taxol indicate the continuing importance of plant species in drug discovery.2 In recent years, a great number of diterpenoids with lathyrane and jatrophane structures have been isolated from Euphorbia species, some of them possessing interesting bioactivity, namely as modulators of multidrug resistance. In this communication, we are reporting on the isolation, structure elucidation and antibacterial activity of four terpenic compounds isolated from the methanolic extract of Euphorbia lagascae aerial parts (figure 1). |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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Isolation of terpenic compounds from the methanolic extract of Euphorbia lagascae. Screening of their in vitro activity against Mycobacterium tuberculosis and Staphylococcus aureusTerpenic compoundsE. lagascaeM. tuberculosisS. aureusFor as long as man can remember, plants have been used worldwide for the treatment of diseases. Today, many of the drugs currently used are derived from natural products or have dependent upon a natural product for their development and the recent discoveries of the antimalarial artemisinin and the anticancer agent taxol indicate the continuing importance of plant species in drug discovery.2 In recent years, a great number of diterpenoids with lathyrane and jatrophane structures have been isolated from Euphorbia species, some of them possessing interesting bioactivity, namely as modulators of multidrug resistance. In this communication, we are reporting on the isolation, structure elucidation and antibacterial activity of four terpenic compounds isolated from the methanolic extract of Euphorbia lagascae aerial parts (figure 1).2012-03-06T11:52:27Z2005-01-01T00:00:00Z2005conference objectinfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10884/473engDuarte, NRamalhete, CátiaMartins, MAbreu, PedroViveiros, MAmaral, LFerreira, MJUinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-10-31T15:59:25Zoai:repositorio-cientifico.uatlantica.pt:10884/473Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-10-31T15:59:25Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Isolation of terpenic compounds from the methanolic extract of Euphorbia lagascae. Screening of their in vitro activity against Mycobacterium tuberculosis and Staphylococcus aureus |
title |
Isolation of terpenic compounds from the methanolic extract of Euphorbia lagascae. Screening of their in vitro activity against Mycobacterium tuberculosis and Staphylococcus aureus |
spellingShingle |
Isolation of terpenic compounds from the methanolic extract of Euphorbia lagascae. Screening of their in vitro activity against Mycobacterium tuberculosis and Staphylococcus aureus Duarte, N Terpenic compounds E. lagascae M. tuberculosis S. aureus |
title_short |
Isolation of terpenic compounds from the methanolic extract of Euphorbia lagascae. Screening of their in vitro activity against Mycobacterium tuberculosis and Staphylococcus aureus |
title_full |
Isolation of terpenic compounds from the methanolic extract of Euphorbia lagascae. Screening of their in vitro activity against Mycobacterium tuberculosis and Staphylococcus aureus |
title_fullStr |
Isolation of terpenic compounds from the methanolic extract of Euphorbia lagascae. Screening of their in vitro activity against Mycobacterium tuberculosis and Staphylococcus aureus |
title_full_unstemmed |
Isolation of terpenic compounds from the methanolic extract of Euphorbia lagascae. Screening of their in vitro activity against Mycobacterium tuberculosis and Staphylococcus aureus |
title_sort |
Isolation of terpenic compounds from the methanolic extract of Euphorbia lagascae. Screening of their in vitro activity against Mycobacterium tuberculosis and Staphylococcus aureus |
author |
Duarte, N |
author_facet |
Duarte, N Ramalhete, Cátia Martins, M Abreu, Pedro Viveiros, M Amaral, L Ferreira, MJU |
author_role |
author |
author2 |
Ramalhete, Cátia Martins, M Abreu, Pedro Viveiros, M Amaral, L Ferreira, MJU |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Duarte, N Ramalhete, Cátia Martins, M Abreu, Pedro Viveiros, M Amaral, L Ferreira, MJU |
dc.subject.por.fl_str_mv |
Terpenic compounds E. lagascae M. tuberculosis S. aureus |
topic |
Terpenic compounds E. lagascae M. tuberculosis S. aureus |
description |
For as long as man can remember, plants have been used worldwide for the treatment of diseases. Today, many of the drugs currently used are derived from natural products or have dependent upon a natural product for their development and the recent discoveries of the antimalarial artemisinin and the anticancer agent taxol indicate the continuing importance of plant species in drug discovery.2 In recent years, a great number of diterpenoids with lathyrane and jatrophane structures have been isolated from Euphorbia species, some of them possessing interesting bioactivity, namely as modulators of multidrug resistance. In this communication, we are reporting on the isolation, structure elucidation and antibacterial activity of four terpenic compounds isolated from the methanolic extract of Euphorbia lagascae aerial parts (figure 1). |
publishDate |
2005 |
dc.date.none.fl_str_mv |
2005-01-01T00:00:00Z 2005 2012-03-06T11:52:27Z |
dc.type.driver.fl_str_mv |
conference object |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10884/473 |
url |
http://hdl.handle.net/10884/473 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
mluisa.alvim@gmail.com |
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1817548668109062144 |