Control of the properties of porous chitosan-alginate membranes through the addition of different proportions of Pluronic F68
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/80376 https://doi.org/10.1016/j.msec.2014.08.014 |
Resumo: | This work addresses the development and characterization of porous chitosan-alginate based polyelectrolyte complexes, obtained by using two different proportions of the biocompatible surfactant Pluronic F68. These biomaterials are proposed for applications as biodegradable and biocompatible wound dressing and/or scaffolds. The results indicate that thickness, roughness, porosity and liquid uptake of the membranes increase with the amount of surfactant used, while their mechanical properties and stability in aqueous media decrease. Other important properties such as color and surface hydrophilicity (water contact angle) are not significantly altered or did not present a clear tendency of variation with the increase of the amount of surfactant added to the polyelectrolyte complexes, such as real density, average pore diameter, total pore volume and surface area. The prepared biomaterials were not cytotoxic to L929 cells. In conclusion, it is possible to tune the physicochemical properties of chitosan-alginate polyelectrolyte complexes, through the variation of the proportion of surfactant (Pluronic F68) added to the mixture, so as to enable the desired application of these biomaterials. |
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7160 |
spelling |
Control of the properties of porous chitosan-alginate membranes through the addition of different proportions of Pluronic F68This work addresses the development and characterization of porous chitosan-alginate based polyelectrolyte complexes, obtained by using two different proportions of the biocompatible surfactant Pluronic F68. These biomaterials are proposed for applications as biodegradable and biocompatible wound dressing and/or scaffolds. The results indicate that thickness, roughness, porosity and liquid uptake of the membranes increase with the amount of surfactant used, while their mechanical properties and stability in aqueous media decrease. Other important properties such as color and surface hydrophilicity (water contact angle) are not significantly altered or did not present a clear tendency of variation with the increase of the amount of surfactant added to the polyelectrolyte complexes, such as real density, average pore diameter, total pore volume and surface area. The prepared biomaterials were not cytotoxic to L929 cells. In conclusion, it is possible to tune the physicochemical properties of chitosan-alginate polyelectrolyte complexes, through the variation of the proportion of surfactant (Pluronic F68) added to the mixture, so as to enable the desired application of these biomaterials.2014-11info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/80376http://hdl.handle.net/10316/80376https://doi.org/10.1016/j.msec.2014.08.014eng1873-019125280687Bueno, Cecilia ZorziDias, Ana Maria AntunesSousa, Hermínio José Cipriano deBraga, Mara Elga MedeirosMoraes, Angela Mariainfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2021-08-23T10:39:53Zoai:estudogeral.uc.pt:10316/80376Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:02:49.001135Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Control of the properties of porous chitosan-alginate membranes through the addition of different proportions of Pluronic F68 |
title |
Control of the properties of porous chitosan-alginate membranes through the addition of different proportions of Pluronic F68 |
spellingShingle |
Control of the properties of porous chitosan-alginate membranes through the addition of different proportions of Pluronic F68 Bueno, Cecilia Zorzi |
title_short |
Control of the properties of porous chitosan-alginate membranes through the addition of different proportions of Pluronic F68 |
title_full |
Control of the properties of porous chitosan-alginate membranes through the addition of different proportions of Pluronic F68 |
title_fullStr |
Control of the properties of porous chitosan-alginate membranes through the addition of different proportions of Pluronic F68 |
title_full_unstemmed |
Control of the properties of porous chitosan-alginate membranes through the addition of different proportions of Pluronic F68 |
title_sort |
Control of the properties of porous chitosan-alginate membranes through the addition of different proportions of Pluronic F68 |
author |
Bueno, Cecilia Zorzi |
author_facet |
Bueno, Cecilia Zorzi Dias, Ana Maria Antunes Sousa, Hermínio José Cipriano de Braga, Mara Elga Medeiros Moraes, Angela Maria |
author_role |
author |
author2 |
Dias, Ana Maria Antunes Sousa, Hermínio José Cipriano de Braga, Mara Elga Medeiros Moraes, Angela Maria |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Bueno, Cecilia Zorzi Dias, Ana Maria Antunes Sousa, Hermínio José Cipriano de Braga, Mara Elga Medeiros Moraes, Angela Maria |
description |
This work addresses the development and characterization of porous chitosan-alginate based polyelectrolyte complexes, obtained by using two different proportions of the biocompatible surfactant Pluronic F68. These biomaterials are proposed for applications as biodegradable and biocompatible wound dressing and/or scaffolds. The results indicate that thickness, roughness, porosity and liquid uptake of the membranes increase with the amount of surfactant used, while their mechanical properties and stability in aqueous media decrease. Other important properties such as color and surface hydrophilicity (water contact angle) are not significantly altered or did not present a clear tendency of variation with the increase of the amount of surfactant added to the polyelectrolyte complexes, such as real density, average pore diameter, total pore volume and surface area. The prepared biomaterials were not cytotoxic to L929 cells. In conclusion, it is possible to tune the physicochemical properties of chitosan-alginate polyelectrolyte complexes, through the variation of the proportion of surfactant (Pluronic F68) added to the mixture, so as to enable the desired application of these biomaterials. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-11 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/80376 http://hdl.handle.net/10316/80376 https://doi.org/10.1016/j.msec.2014.08.014 |
url |
http://hdl.handle.net/10316/80376 https://doi.org/10.1016/j.msec.2014.08.014 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1873-0191 25280687 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799133920902512641 |