Idiopathic retroperitoneal fibrosis: atypical evolution

• Autor(a) principal: Murinello, António
• Data de Publicação: 2005
• Outros Autores: Braz, Sandra, Gonçalves, Aline
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: https://revista.spmi.pt/index.php/rpmi/article/view/1707
• topic: fibrose retroperitoneal; corticosteroides; azatioprina; idiopathic; retroperitoneal fibrosis; corticosteroids

The authors present a clinical report of a 68 year old woman, who had spontaneous clinical and laboratory amelioration of serious acute renal failure due to idiopathic retroperitoneal fibrosis, which was demonstrated on histologic examination of a surgical biopsy. Therapy with corticosteroids and implantation of bilateral ureteral stents were decided in view of laboratory signs of persistence of disease activity. The clinical and laboratory evolution was good and ureteral stents were removed at four months duration of corticosteroid therapy. A slow and progressive lower dosage of corticosteroids do not caused a recurrence of the disease, but due to the persistence of imagiological signs of ureteral dilation, azatioprine was associated to corticosteroids, trying to maintain stabilization of the disease without needing to recur to ureterolysis surgery.The authors made bibliographic review of data on idiopathic retroperitoneal fibrosis, focusing on etiopathogeny, clinical presentation and diagnosis, therapy and prognosis.