Local piezoresponse and polarization switching in nucleobase thymine microcrystals

Detalhes bibliográficos
Autor(a) principal: Bdikin, Igor
Data de Publicação: 2015
Outros Autores: Heredia, Alejandro, Neumayer, Sabine M., Bystrov, Vladimir S., Gracio, Jose, Rodriguez, Brian J., Kholkin, Andrei L.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10773/20574
Resumo: Thymine (2-oxy-4-oxy-5 methyl pyrimidine) is one of the four nucleobases of deoxyribonucleic acid (DNA). In the DNA molecule, thymine binds to adenine via two hydrogen bonds, thus stabilizing the nucleic acid structure and is involved in pairing and replication. Here, we show that synthetic thymine microcrystals grown from the solution exhibit local piezoelectricity and apparent ferroelectricity, as evidenced by nanoscale electromechanical measurements via Piezoresponse Force Microscopy. Our experimental results demonstrate significant electromechanical activity and polarization switchability of thymine, thus opening a pathway for piezoelectric and ferroelectric-based applications of thymine and, perhaps, of other DNA nucleobase materials. The results are supported by molecular modeling of polarization switching under an external electric field. (C) 2015 AIP Publishing LLC.
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spelling Local piezoresponse and polarization switching in nucleobase thymine microcrystalsSCANNING PROBE MICROSCOPYATOMIC-FORCE MICROSCOPYDNA DOUBLE HELIXTHIN-FILMSPEPTIDE NANOTUBESCRYSTAL STRUCTUREELECTRON-TRANSFERNUCLEIC-ACIDSNANOSCALEPIEZOELECTRICITYThymine (2-oxy-4-oxy-5 methyl pyrimidine) is one of the four nucleobases of deoxyribonucleic acid (DNA). In the DNA molecule, thymine binds to adenine via two hydrogen bonds, thus stabilizing the nucleic acid structure and is involved in pairing and replication. Here, we show that synthetic thymine microcrystals grown from the solution exhibit local piezoelectricity and apparent ferroelectricity, as evidenced by nanoscale electromechanical measurements via Piezoresponse Force Microscopy. Our experimental results demonstrate significant electromechanical activity and polarization switchability of thymine, thus opening a pathway for piezoelectric and ferroelectric-based applications of thymine and, perhaps, of other DNA nucleobase materials. The results are supported by molecular modeling of polarization switching under an external electric field. (C) 2015 AIP Publishing LLC.AMER INST PHYSICS2017-12-07T19:51:57Z2015-01-01T00:00:00Z2015info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10773/20574eng0021-897910.1063/1.4927806Bdikin, IgorHeredia, AlejandroNeumayer, Sabine M.Bystrov, Vladimir S.Gracio, JoseRodriguez, Brian J.Kholkin, Andrei L.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-22T11:40:26Zoai:ria.ua.pt:10773/20574Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:55:15.117760Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Local piezoresponse and polarization switching in nucleobase thymine microcrystals
title Local piezoresponse and polarization switching in nucleobase thymine microcrystals
spellingShingle Local piezoresponse and polarization switching in nucleobase thymine microcrystals
Bdikin, Igor
SCANNING PROBE MICROSCOPY
ATOMIC-FORCE MICROSCOPY
DNA DOUBLE HELIX
THIN-FILMS
PEPTIDE NANOTUBES
CRYSTAL STRUCTURE
ELECTRON-TRANSFER
NUCLEIC-ACIDS
NANOSCALE
PIEZOELECTRICITY
title_short Local piezoresponse and polarization switching in nucleobase thymine microcrystals
title_full Local piezoresponse and polarization switching in nucleobase thymine microcrystals
title_fullStr Local piezoresponse and polarization switching in nucleobase thymine microcrystals
title_full_unstemmed Local piezoresponse and polarization switching in nucleobase thymine microcrystals
title_sort Local piezoresponse and polarization switching in nucleobase thymine microcrystals
author Bdikin, Igor
author_facet Bdikin, Igor
Heredia, Alejandro
Neumayer, Sabine M.
Bystrov, Vladimir S.
Gracio, Jose
Rodriguez, Brian J.
Kholkin, Andrei L.
author_role author
author2 Heredia, Alejandro
Neumayer, Sabine M.
Bystrov, Vladimir S.
Gracio, Jose
Rodriguez, Brian J.
Kholkin, Andrei L.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Bdikin, Igor
Heredia, Alejandro
Neumayer, Sabine M.
Bystrov, Vladimir S.
Gracio, Jose
Rodriguez, Brian J.
Kholkin, Andrei L.
dc.subject.por.fl_str_mv SCANNING PROBE MICROSCOPY
ATOMIC-FORCE MICROSCOPY
DNA DOUBLE HELIX
THIN-FILMS
PEPTIDE NANOTUBES
CRYSTAL STRUCTURE
ELECTRON-TRANSFER
NUCLEIC-ACIDS
NANOSCALE
PIEZOELECTRICITY
topic SCANNING PROBE MICROSCOPY
ATOMIC-FORCE MICROSCOPY
DNA DOUBLE HELIX
THIN-FILMS
PEPTIDE NANOTUBES
CRYSTAL STRUCTURE
ELECTRON-TRANSFER
NUCLEIC-ACIDS
NANOSCALE
PIEZOELECTRICITY
description Thymine (2-oxy-4-oxy-5 methyl pyrimidine) is one of the four nucleobases of deoxyribonucleic acid (DNA). In the DNA molecule, thymine binds to adenine via two hydrogen bonds, thus stabilizing the nucleic acid structure and is involved in pairing and replication. Here, we show that synthetic thymine microcrystals grown from the solution exhibit local piezoelectricity and apparent ferroelectricity, as evidenced by nanoscale electromechanical measurements via Piezoresponse Force Microscopy. Our experimental results demonstrate significant electromechanical activity and polarization switchability of thymine, thus opening a pathway for piezoelectric and ferroelectric-based applications of thymine and, perhaps, of other DNA nucleobase materials. The results are supported by molecular modeling of polarization switching under an external electric field. (C) 2015 AIP Publishing LLC.
publishDate 2015
dc.date.none.fl_str_mv 2015-01-01T00:00:00Z
2015
2017-12-07T19:51:57Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10773/20574
url http://hdl.handle.net/10773/20574
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0021-8979
10.1063/1.4927806
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv AMER INST PHYSICS
publisher.none.fl_str_mv AMER INST PHYSICS
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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