An updated overview on nanonutraceuticals: focus on nanoprebiotics and nanoprobiotics
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/64981 |
Resumo: | Over the last few years, the application of nanotechnology to nutraceuticals has been rapidly growing due to its ability to enhance the bioavailability of the loaded active ingredients, resulting in improved therapeutic/nutraceutical outcomes. The focus of this work is nanoprebiotics and nanoprobiotics, terms which stand for the loading of a set of compounds (e.g., prebiotics, probiotics, and synbiotics) in nanoparticles that work as absorption enhancers in the gastrointestinal tract. In this manuscript, the main features of prebiotics and probiotics are highlighted, together with the discussion of emerging applications of nanotechnologies in their formulation. Current research strategies are also discussed, in particular the promising use of nanofibers for the delivery of probiotics. Synbiotic-based nanoparticles represent an innovative trend within this area of interest. As only few experimental studies on nanoprebiotics and nanoprobiotics are available in the scientific literature, research on this prominent field is needed, covering effectiveness, bioavailability, and safety aspects. |
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An updated overview on nanonutraceuticals: focus on nanoprebiotics and nanoprobioticsnutraceuticalsnanotechnologiesnanonutraceuticalsprebioticsprobioticssynbioticsScience & TechnologyOver the last few years, the application of nanotechnology to nutraceuticals has been rapidly growing due to its ability to enhance the bioavailability of the loaded active ingredients, resulting in improved therapeutic/nutraceutical outcomes. The focus of this work is nanoprebiotics and nanoprobiotics, terms which stand for the loading of a set of compounds (e.g., prebiotics, probiotics, and synbiotics) in nanoparticles that work as absorption enhancers in the gastrointestinal tract. In this manuscript, the main features of prebiotics and probiotics are highlighted, together with the discussion of emerging applications of nanotechnologies in their formulation. Current research strategies are also discussed, in particular the promising use of nanofibers for the delivery of probiotics. Synbiotic-based nanoparticles represent an innovative trend within this area of interest. As only few experimental studies on nanoprebiotics and nanoprobiotics are available in the scientific literature, research on this prominent field is needed, covering effectiveness, bioavailability, and safety aspects.The authors acknowledge the support of the research project: Nutraceutica come supporto nutrizionale nel paziente oncologico, CUP: B83D18000140007. E. B. Souto acknowledges the sponsorship of the projects M-ERA-NET-0004/2015-PAIRED and UIDB/04469/2020 (strategic fund), receiving support from the Portuguese Science and Technology Foundation, Ministry of Science and Education (FCT/MEC) through national funds, and co-financed by FEDER, under the Partnership Agreement PT2020.info:eu-repo/semantics/publishedVersionMDPIUniversidade do MinhoDurazzo, AlessandraNazhand, AmhirosseinLucarini, MassimoAtanasov, Atanas G.Souto, Eliana B.Novellino, EttoreCapasso, RaffaeleSantini, Antonello2020-03-262020-03-26T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/64981engDurazzo, Alessandra; Nazhand, Amhirossein; Lucarini, Massimo; Atanasov, Atanas G.; Souto, Eliana; Novellino, Ettore; Capasso, Raffaele; Santini, Antonello, An updated overview on nanonutraceuticals: focus on nanoprebiotics and nanoprobiotics. International Journal of Molecular Sciences, 21(7), 2285, 20201424-67831422-00671661-659610.3390/ijms2107228532225036https://www.mdpi.com/1422-0067/21/7/2285info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:03:03Zoai:repositorium.sdum.uminho.pt:1822/64981Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:53:08.314899Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
An updated overview on nanonutraceuticals: focus on nanoprebiotics and nanoprobiotics |
title |
An updated overview on nanonutraceuticals: focus on nanoprebiotics and nanoprobiotics |
spellingShingle |
An updated overview on nanonutraceuticals: focus on nanoprebiotics and nanoprobiotics Durazzo, Alessandra nutraceuticals nanotechnologies nanonutraceuticals prebiotics probiotics synbiotics Science & Technology |
title_short |
An updated overview on nanonutraceuticals: focus on nanoprebiotics and nanoprobiotics |
title_full |
An updated overview on nanonutraceuticals: focus on nanoprebiotics and nanoprobiotics |
title_fullStr |
An updated overview on nanonutraceuticals: focus on nanoprebiotics and nanoprobiotics |
title_full_unstemmed |
An updated overview on nanonutraceuticals: focus on nanoprebiotics and nanoprobiotics |
title_sort |
An updated overview on nanonutraceuticals: focus on nanoprebiotics and nanoprobiotics |
author |
Durazzo, Alessandra |
author_facet |
Durazzo, Alessandra Nazhand, Amhirossein Lucarini, Massimo Atanasov, Atanas G. Souto, Eliana B. Novellino, Ettore Capasso, Raffaele Santini, Antonello |
author_role |
author |
author2 |
Nazhand, Amhirossein Lucarini, Massimo Atanasov, Atanas G. Souto, Eliana B. Novellino, Ettore Capasso, Raffaele Santini, Antonello |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Durazzo, Alessandra Nazhand, Amhirossein Lucarini, Massimo Atanasov, Atanas G. Souto, Eliana B. Novellino, Ettore Capasso, Raffaele Santini, Antonello |
dc.subject.por.fl_str_mv |
nutraceuticals nanotechnologies nanonutraceuticals prebiotics probiotics synbiotics Science & Technology |
topic |
nutraceuticals nanotechnologies nanonutraceuticals prebiotics probiotics synbiotics Science & Technology |
description |
Over the last few years, the application of nanotechnology to nutraceuticals has been rapidly growing due to its ability to enhance the bioavailability of the loaded active ingredients, resulting in improved therapeutic/nutraceutical outcomes. The focus of this work is nanoprebiotics and nanoprobiotics, terms which stand for the loading of a set of compounds (e.g., prebiotics, probiotics, and synbiotics) in nanoparticles that work as absorption enhancers in the gastrointestinal tract. In this manuscript, the main features of prebiotics and probiotics are highlighted, together with the discussion of emerging applications of nanotechnologies in their formulation. Current research strategies are also discussed, in particular the promising use of nanofibers for the delivery of probiotics. Synbiotic-based nanoparticles represent an innovative trend within this area of interest. As only few experimental studies on nanoprebiotics and nanoprobiotics are available in the scientific literature, research on this prominent field is needed, covering effectiveness, bioavailability, and safety aspects. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-03-26 2020-03-26T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/64981 |
url |
http://hdl.handle.net/1822/64981 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Durazzo, Alessandra; Nazhand, Amhirossein; Lucarini, Massimo; Atanasov, Atanas G.; Souto, Eliana; Novellino, Ettore; Capasso, Raffaele; Santini, Antonello, An updated overview on nanonutraceuticals: focus on nanoprebiotics and nanoprobiotics. International Journal of Molecular Sciences, 21(7), 2285, 2020 1424-6783 1422-0067 1661-6596 10.3390/ijms21072285 32225036 https://www.mdpi.com/1422-0067/21/7/2285 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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