Accuracy of prenatal culture in predicting intrapartum group B streptococcus colonization status

• Autor(a) principal: Florindo, C.
• Data de Publicação: 2014
• Outros Autores: Damião, V., Lima, J., Nogueira, I., Rocha, I., Caetano, P., Ribeiro, L., Viegas, S., Gomes, João Paulo, Borrego, M.J.
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: http://hdl.handle.net/10400.18/2975
• topic: Early Onset Disease; Streptococcus agalactiae; Intrapartum Antibiotic Prophylaxis; Intrapartum Screening; Infecções Sexualmente Transmissíveis

Objective: To evaluate the positive predictive value (PPV) of group B Streptococcus (GBS) cultures at 35–37 weeks of gestation relative to GBS colonization status at delivery. Methods: Rectovaginal swabs from 221 women at labor in four Lisbon hospitals were collected for GBS screening according to the CDC guidelines. Results: The PPV was 24.4%. IAP was administered to 100% of prenatally GBS positive women. There was no case of early onset GBS disease (EOD). Conclusions: Poor accuracy of prenatal cultures in identifying true candidates for IAP highlights the need for Portuguese clinical and laboratory guidelines to prevent EOD and antibiotic overtreatment of pregnant women.