Hidden hospital mortality in patients with sepsis discharged from the intensive care unit

Detalhes bibliográficos
Autor(a) principal: Aguiar-Ricardo, I
Data de Publicação: 2019
Outros Autores: Mateus, H, Gonçalves-Pereira, J
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.26/30857
Resumo: OBJECTIVE: To evaluate the impact of the presence of sepsis on in-hospital mortality after intensive care unit discharge. METHODS: Retrospective, observational, single-center study. All consecutive patients discharged alive from the intensive care unit of Hospital Vila Franca de Xira (Portugal) from January 1 to December 31, 2015 (N = 473) were included and followed until death or hospital discharge. In-hospital mortality after intensive care unit discharge was calculated for septic and non-septic patients. RESULTS: A total of 61 patients (12.9%) died in the hospital after being discharged alive from the intensive care unit. This rate was higher among the patients with sepsis on admission, 21.4%, whereas the in-hospital, post-intensive care unit mortality rate for the remaining patients was nearly half that, 9.3% (p < 0.001). Other patient characteristics associated with mortality were advanced age (p = 0.02), male sex (p < 0.001), lower body mass index (p = 0.02), end-stage renal disease (p = 0.04) and high Simplified Acute Physiology Score II (SAPS II) at intensive care unit admission (p < 0.001), the presence of shock (p < 0.001) and medical admission (p < 0.001). We developed a logistic regression model and identified the independent predictors of in-hospital mortality after intensive care unit discharge. CONCLUSION: Admission to the intensive care unit with a sepsis diagnosis is associated with an increased risk of dying in the hospital, not only in the intensive care unit but also after resolution of the acute process and discharge from the intensive care unit.
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spelling Hidden hospital mortality in patients with sepsis discharged from the intensive care unitMortalidade HospitalarUnidades de Cuidados IntensivosOBJECTIVE: To evaluate the impact of the presence of sepsis on in-hospital mortality after intensive care unit discharge. METHODS: Retrospective, observational, single-center study. All consecutive patients discharged alive from the intensive care unit of Hospital Vila Franca de Xira (Portugal) from January 1 to December 31, 2015 (N = 473) were included and followed until death or hospital discharge. In-hospital mortality after intensive care unit discharge was calculated for septic and non-septic patients. RESULTS: A total of 61 patients (12.9%) died in the hospital after being discharged alive from the intensive care unit. This rate was higher among the patients with sepsis on admission, 21.4%, whereas the in-hospital, post-intensive care unit mortality rate for the remaining patients was nearly half that, 9.3% (p < 0.001). Other patient characteristics associated with mortality were advanced age (p = 0.02), male sex (p < 0.001), lower body mass index (p = 0.02), end-stage renal disease (p = 0.04) and high Simplified Acute Physiology Score II (SAPS II) at intensive care unit admission (p < 0.001), the presence of shock (p < 0.001) and medical admission (p < 0.001). We developed a logistic regression model and identified the independent predictors of in-hospital mortality after intensive care unit discharge. CONCLUSION: Admission to the intensive care unit with a sepsis diagnosis is associated with an increased risk of dying in the hospital, not only in the intensive care unit but also after resolution of the acute process and discharge from the intensive care unit.Repositório ComumAguiar-Ricardo, IMateus, HGonçalves-Pereira, J2020-01-12T20:17:19Z2019-06-102019-06-10T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/30857engRev Bras Ter Intensiva. 2019 Jun 10;31(2):122-128.10.5935/0103-507X.20190037info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-10T05:02:00Zoai:comum.rcaap.pt:10400.26/30857Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:35:39.084121Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Hidden hospital mortality in patients with sepsis discharged from the intensive care unit
title Hidden hospital mortality in patients with sepsis discharged from the intensive care unit
spellingShingle Hidden hospital mortality in patients with sepsis discharged from the intensive care unit
Aguiar-Ricardo, I
Mortalidade Hospitalar
Unidades de Cuidados Intensivos
title_short Hidden hospital mortality in patients with sepsis discharged from the intensive care unit
title_full Hidden hospital mortality in patients with sepsis discharged from the intensive care unit
title_fullStr Hidden hospital mortality in patients with sepsis discharged from the intensive care unit
title_full_unstemmed Hidden hospital mortality in patients with sepsis discharged from the intensive care unit
title_sort Hidden hospital mortality in patients with sepsis discharged from the intensive care unit
author Aguiar-Ricardo, I
author_facet Aguiar-Ricardo, I
Mateus, H
Gonçalves-Pereira, J
author_role author
author2 Mateus, H
Gonçalves-Pereira, J
author2_role author
author
dc.contributor.none.fl_str_mv Repositório Comum
dc.contributor.author.fl_str_mv Aguiar-Ricardo, I
Mateus, H
Gonçalves-Pereira, J
dc.subject.por.fl_str_mv Mortalidade Hospitalar
Unidades de Cuidados Intensivos
topic Mortalidade Hospitalar
Unidades de Cuidados Intensivos
description OBJECTIVE: To evaluate the impact of the presence of sepsis on in-hospital mortality after intensive care unit discharge. METHODS: Retrospective, observational, single-center study. All consecutive patients discharged alive from the intensive care unit of Hospital Vila Franca de Xira (Portugal) from January 1 to December 31, 2015 (N = 473) were included and followed until death or hospital discharge. In-hospital mortality after intensive care unit discharge was calculated for septic and non-septic patients. RESULTS: A total of 61 patients (12.9%) died in the hospital after being discharged alive from the intensive care unit. This rate was higher among the patients with sepsis on admission, 21.4%, whereas the in-hospital, post-intensive care unit mortality rate for the remaining patients was nearly half that, 9.3% (p < 0.001). Other patient characteristics associated with mortality were advanced age (p = 0.02), male sex (p < 0.001), lower body mass index (p = 0.02), end-stage renal disease (p = 0.04) and high Simplified Acute Physiology Score II (SAPS II) at intensive care unit admission (p < 0.001), the presence of shock (p < 0.001) and medical admission (p < 0.001). We developed a logistic regression model and identified the independent predictors of in-hospital mortality after intensive care unit discharge. CONCLUSION: Admission to the intensive care unit with a sepsis diagnosis is associated with an increased risk of dying in the hospital, not only in the intensive care unit but also after resolution of the acute process and discharge from the intensive care unit.
publishDate 2019
dc.date.none.fl_str_mv 2019-06-10
2019-06-10T00:00:00Z
2020-01-12T20:17:19Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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format article
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/30857
url http://hdl.handle.net/10400.26/30857
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Rev Bras Ter Intensiva. 2019 Jun 10;31(2):122-128.
10.5935/0103-507X.20190037
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eu_rights_str_mv openAccess
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dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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