Tuning polymeric and drug properties in a drug eluting stent: A numerical study

Detalhes bibliográficos
Autor(a) principal: Naghipoor, Jahed
Data de Publicação: 2016
Outros Autores: Ferreira, José Augusto, Oliveira, Paula de, Rabczuk, Timon
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10316/45268
https://doi.org/10.1016/j.apm.2016.04.001
Resumo: A two dimensional coupled nonlinear non-Fickian model for drug release from a biodegradable drug eluting stent into the arterial wall is studied. The influence of porosity and degradation of the polymer as well as the dissolution rate of the drug are analyzed. Numerical simulations that illustrate the kind of dependence of drug profiles on these properties are included.
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spelling Tuning polymeric and drug properties in a drug eluting stent: A numerical studyA two dimensional coupled nonlinear non-Fickian model for drug release from a biodegradable drug eluting stent into the arterial wall is studied. The influence of porosity and degradation of the polymer as well as the dissolution rate of the drug are analyzed. Numerical simulations that illustrate the kind of dependence of drug profiles on these properties are included.Elsevier2016info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/45268http://hdl.handle.net/10316/45268https://doi.org/10.1016/j.apm.2016.04.001https://doi.org/10.1016/j.apm.2016.04.001enghttps://doi.org/10.1016/j.apm.2016.04.001Naghipoor, JahedFerreira, José AugustoOliveira, Paula deRabczuk, Timoninfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2021-06-29T10:02:57Zoai:estudogeral.uc.pt:10316/45268Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:53:21.982170Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Tuning polymeric and drug properties in a drug eluting stent: A numerical study
title Tuning polymeric and drug properties in a drug eluting stent: A numerical study
spellingShingle Tuning polymeric and drug properties in a drug eluting stent: A numerical study
Naghipoor, Jahed
title_short Tuning polymeric and drug properties in a drug eluting stent: A numerical study
title_full Tuning polymeric and drug properties in a drug eluting stent: A numerical study
title_fullStr Tuning polymeric and drug properties in a drug eluting stent: A numerical study
title_full_unstemmed Tuning polymeric and drug properties in a drug eluting stent: A numerical study
title_sort Tuning polymeric and drug properties in a drug eluting stent: A numerical study
author Naghipoor, Jahed
author_facet Naghipoor, Jahed
Ferreira, José Augusto
Oliveira, Paula de
Rabczuk, Timon
author_role author
author2 Ferreira, José Augusto
Oliveira, Paula de
Rabczuk, Timon
author2_role author
author
author
dc.contributor.author.fl_str_mv Naghipoor, Jahed
Ferreira, José Augusto
Oliveira, Paula de
Rabczuk, Timon
description A two dimensional coupled nonlinear non-Fickian model for drug release from a biodegradable drug eluting stent into the arterial wall is studied. The influence of porosity and degradation of the polymer as well as the dissolution rate of the drug are analyzed. Numerical simulations that illustrate the kind of dependence of drug profiles on these properties are included.
publishDate 2016
dc.date.none.fl_str_mv 2016
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10316/45268
http://hdl.handle.net/10316/45268
https://doi.org/10.1016/j.apm.2016.04.001
https://doi.org/10.1016/j.apm.2016.04.001
url http://hdl.handle.net/10316/45268
https://doi.org/10.1016/j.apm.2016.04.001
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://doi.org/10.1016/j.apm.2016.04.001
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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