Acetyl Cholinesterase Inhibitors and Cell-Derived Peripheral Inflammatory Cytokines in Early Stages of Alzheimer's Disease
Autor(a) principal: | |
---|---|
Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/1822/57865 |
Resumo: | Clinical and preclinical studies firmly support the involvement of the inflammation in the pathogenesis of Alzheimer's disease (AD). Despite acetylcholinesterase inhibitors (AChEI) being widely used in AD patients, there is no conclusive evidence about their impact on the inflammatory response. |
id |
RCAP_dccbbe5c3bdd1b33d28180d16c7a14c6 |
---|---|
oai_identifier_str |
oai:repositorium.sdum.uminho.pt:1822/57865 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Acetyl Cholinesterase Inhibitors and Cell-Derived Peripheral Inflammatory Cytokines in Early Stages of Alzheimer's DiseaseAgedAlzheimer DiseaseCholinesterase InhibitorsCytokinesDonepezilFemaleFollow-Up StudiesHumansIndansInflammationMaleMiddle AgedPiperidinesAlzheimer's diseaseanticholinesterase inhibitorsScience & TechnologyClinical and preclinical studies firmly support the involvement of the inflammation in the pathogenesis of Alzheimer's disease (AD). Despite acetylcholinesterase inhibitors (AChEI) being widely used in AD patients, there is no conclusive evidence about their impact on the inflammatory response.Funding was received from a program co-financed by the European Social Fund and the Greek State (GSRT LS5-3808)info:eu-repo/semantics/publishedVersionWolters Kluwer HealthUniversidade do MinhoKokras, NikolaosStamouli, EvangeliaSotiropoulos, I.Katirtzoglou, Everina A.Siarkos, Kostas T.Dalagiorgou, GeorgiaAlexandraki, Krystallenia I.Coulocheri, StavroulaPiperi, ChristinaPolitis, Antonios M.2018-042018-04-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/57865engKokras, N., Stamouli, E., Sotiropoulos, I., Katirtzoglou, E. A., Siarkos, K. T., Dalagiorgou, G., ... & Politis, A. M. (2018). Acetyl Cholinesterase Inhibitors and Cell-Derived Peripheral Inflammatory Cytokines in Early Stages of Alzheimer's Disease. Journal of clinical psychopharmacology, 38(2), 138-1430271-07491533-712X10.1097/JCP.000000000000084029420357https://journals.lww.com/psychopharmacology/Abstract/2018/04000/Acetyl_Cholinesterase_Inhibitors_and_Cell_Derived.9.aspxinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:01:24Zoai:repositorium.sdum.uminho.pt:1822/57865Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:51:18.460150Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Acetyl Cholinesterase Inhibitors and Cell-Derived Peripheral Inflammatory Cytokines in Early Stages of Alzheimer's Disease |
title |
Acetyl Cholinesterase Inhibitors and Cell-Derived Peripheral Inflammatory Cytokines in Early Stages of Alzheimer's Disease |
spellingShingle |
Acetyl Cholinesterase Inhibitors and Cell-Derived Peripheral Inflammatory Cytokines in Early Stages of Alzheimer's Disease Kokras, Nikolaos Aged Alzheimer Disease Cholinesterase Inhibitors Cytokines Donepezil Female Follow-Up Studies Humans Indans Inflammation Male Middle Aged Piperidines Alzheimer's disease anticholinesterase inhibitors Science & Technology |
title_short |
Acetyl Cholinesterase Inhibitors and Cell-Derived Peripheral Inflammatory Cytokines in Early Stages of Alzheimer's Disease |
title_full |
Acetyl Cholinesterase Inhibitors and Cell-Derived Peripheral Inflammatory Cytokines in Early Stages of Alzheimer's Disease |
title_fullStr |
Acetyl Cholinesterase Inhibitors and Cell-Derived Peripheral Inflammatory Cytokines in Early Stages of Alzheimer's Disease |
title_full_unstemmed |
Acetyl Cholinesterase Inhibitors and Cell-Derived Peripheral Inflammatory Cytokines in Early Stages of Alzheimer's Disease |
title_sort |
Acetyl Cholinesterase Inhibitors and Cell-Derived Peripheral Inflammatory Cytokines in Early Stages of Alzheimer's Disease |
author |
Kokras, Nikolaos |
author_facet |
Kokras, Nikolaos Stamouli, Evangelia Sotiropoulos, I. Katirtzoglou, Everina A. Siarkos, Kostas T. Dalagiorgou, Georgia Alexandraki, Krystallenia I. Coulocheri, Stavroula Piperi, Christina Politis, Antonios M. |
author_role |
author |
author2 |
Stamouli, Evangelia Sotiropoulos, I. Katirtzoglou, Everina A. Siarkos, Kostas T. Dalagiorgou, Georgia Alexandraki, Krystallenia I. Coulocheri, Stavroula Piperi, Christina Politis, Antonios M. |
author2_role |
author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Kokras, Nikolaos Stamouli, Evangelia Sotiropoulos, I. Katirtzoglou, Everina A. Siarkos, Kostas T. Dalagiorgou, Georgia Alexandraki, Krystallenia I. Coulocheri, Stavroula Piperi, Christina Politis, Antonios M. |
dc.subject.por.fl_str_mv |
Aged Alzheimer Disease Cholinesterase Inhibitors Cytokines Donepezil Female Follow-Up Studies Humans Indans Inflammation Male Middle Aged Piperidines Alzheimer's disease anticholinesterase inhibitors Science & Technology |
topic |
Aged Alzheimer Disease Cholinesterase Inhibitors Cytokines Donepezil Female Follow-Up Studies Humans Indans Inflammation Male Middle Aged Piperidines Alzheimer's disease anticholinesterase inhibitors Science & Technology |
description |
Clinical and preclinical studies firmly support the involvement of the inflammation in the pathogenesis of Alzheimer's disease (AD). Despite acetylcholinesterase inhibitors (AChEI) being widely used in AD patients, there is no conclusive evidence about their impact on the inflammatory response. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-04 2018-04-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/57865 |
url |
http://hdl.handle.net/1822/57865 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Kokras, N., Stamouli, E., Sotiropoulos, I., Katirtzoglou, E. A., Siarkos, K. T., Dalagiorgou, G., ... & Politis, A. M. (2018). Acetyl Cholinesterase Inhibitors and Cell-Derived Peripheral Inflammatory Cytokines in Early Stages of Alzheimer's Disease. Journal of clinical psychopharmacology, 38(2), 138-143 0271-0749 1533-712X 10.1097/JCP.0000000000000840 29420357 https://journals.lww.com/psychopharmacology/Abstract/2018/04000/Acetyl_Cholinesterase_Inhibitors_and_Cell_Derived.9.aspx |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Wolters Kluwer Health |
publisher.none.fl_str_mv |
Wolters Kluwer Health |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799132285080961024 |