Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10198/4158 |
Resumo: | The industrial processing of mangosteen (Garcinia mangostana L.) generates high amounts of waste, as similar to 60% of the fruit is formed by an inedible pericarp. However, its pericarp has been explored as a source of xanthones; nevertheless, studies addressing the recovery of other chemical compounds from such biomass are still scarce. Hence, this study intended to elucidate the chemical composition of the mangosteen pericarp, including fat-soluble (tocopherols and fatty acids) and water-soluble (organic acids and phenolic compound non-xanthones) compounds present in the following extracts: hydroethanolic (MT80), ethanolic (MTE), and aqueous (MTW). In addition, the antioxidant, anti-inflammatory, antiproliferative and antibacterial potentials of the extracts were assessed. The mangosteen pericarp showed a composition with seven organic acids, three tocopherol isomers, four fatty acids and fifteen phenolic compounds. Regarding the extraction of phenolics, the MT80 was the most efficient (54 mg/g extract), followed by MTE (19.79 mg/g extract) and MTW (4.011 mg/g extract). All extracts showed antioxidant and antibacterial activities; however, MT80 and MTE extracts were more efficient than MTW. Only MTW did not show anti-inflammatory properties, whereas MTE and MT80 showed inhibitory activities towards tumor cell lines. Notwithstanding, MTE showed cytotoxicity towards normal cells. Our findings support the idea that the ripe mangosteen pericarp is a source of bioactive compounds, although their recovery is dependent on the extraction solvent. |
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Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarpFood waste recoveryBioactive compoundsFlavonoidsAntiproliferative activityFood supplementThe industrial processing of mangosteen (Garcinia mangostana L.) generates high amounts of waste, as similar to 60% of the fruit is formed by an inedible pericarp. However, its pericarp has been explored as a source of xanthones; nevertheless, studies addressing the recovery of other chemical compounds from such biomass are still scarce. Hence, this study intended to elucidate the chemical composition of the mangosteen pericarp, including fat-soluble (tocopherols and fatty acids) and water-soluble (organic acids and phenolic compound non-xanthones) compounds present in the following extracts: hydroethanolic (MT80), ethanolic (MTE), and aqueous (MTW). In addition, the antioxidant, anti-inflammatory, antiproliferative and antibacterial potentials of the extracts were assessed. The mangosteen pericarp showed a composition with seven organic acids, three tocopherol isomers, four fatty acids and fifteen phenolic compounds. Regarding the extraction of phenolics, the MT80 was the most efficient (54 mg/g extract), followed by MTE (19.79 mg/g extract) and MTW (4.011 mg/g extract). All extracts showed antioxidant and antibacterial activities; however, MT80 and MTE extracts were more efficient than MTW. Only MTW did not show anti-inflammatory properties, whereas MTE and MT80 showed inhibitory activities towards tumor cell lines. Notwithstanding, MTE showed cytotoxicity towards normal cells. Our findings support the idea that the ripe mangosteen pericarp is a source of bioactive compounds, although their recovery is dependent on the extraction solvent.MDPIBiblioteca Digital do IPBAlbuquerque, Bianca R.Dias, Maria InêsPinela, JoséCalhelha, Ricardo C.Pires, Tânia C.S.P.Alves, Maria JoséCorrêa, Rúbia C.G.Ferreira, Isabel C.F.R.Oliveira, BeatrizBarros, Lillian2011-05-04T10:59:38Z20232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/4158engAlbuquerque, Bianca R.; Dias, Maria Inês; Pinela, José; Calhelha, Ricardo C.; Pires, Tânia C.S.P.; Alves, Maria José; Corrêa, Rúbia C.G.; Ferreira, Isabel C.F.R.; Oliveira, M. Beatriz P. P.; Barros, Lillian (2023). Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp. Foods. eISSN 2304-8158. 12:5, p. 1-1510.3390/foods120509942304-8158info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-07T01:17:51Zoai:bibliotecadigital.ipb.pt:10198/4158Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:56:42.046132Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp |
title |
Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp |
spellingShingle |
Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp Albuquerque, Bianca R. Food waste recovery Bioactive compounds Flavonoids Antiproliferative activity Food supplement |
title_short |
Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp |
title_full |
Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp |
title_fullStr |
Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp |
title_full_unstemmed |
Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp |
title_sort |
Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp |
author |
Albuquerque, Bianca R. |
author_facet |
Albuquerque, Bianca R. Dias, Maria Inês Pinela, José Calhelha, Ricardo C. Pires, Tânia C.S.P. Alves, Maria José Corrêa, Rúbia C.G. Ferreira, Isabel C.F.R. Oliveira, Beatriz Barros, Lillian |
author_role |
author |
author2 |
Dias, Maria Inês Pinela, José Calhelha, Ricardo C. Pires, Tânia C.S.P. Alves, Maria José Corrêa, Rúbia C.G. Ferreira, Isabel C.F.R. Oliveira, Beatriz Barros, Lillian |
author2_role |
author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Biblioteca Digital do IPB |
dc.contributor.author.fl_str_mv |
Albuquerque, Bianca R. Dias, Maria Inês Pinela, José Calhelha, Ricardo C. Pires, Tânia C.S.P. Alves, Maria José Corrêa, Rúbia C.G. Ferreira, Isabel C.F.R. Oliveira, Beatriz Barros, Lillian |
dc.subject.por.fl_str_mv |
Food waste recovery Bioactive compounds Flavonoids Antiproliferative activity Food supplement |
topic |
Food waste recovery Bioactive compounds Flavonoids Antiproliferative activity Food supplement |
description |
The industrial processing of mangosteen (Garcinia mangostana L.) generates high amounts of waste, as similar to 60% of the fruit is formed by an inedible pericarp. However, its pericarp has been explored as a source of xanthones; nevertheless, studies addressing the recovery of other chemical compounds from such biomass are still scarce. Hence, this study intended to elucidate the chemical composition of the mangosteen pericarp, including fat-soluble (tocopherols and fatty acids) and water-soluble (organic acids and phenolic compound non-xanthones) compounds present in the following extracts: hydroethanolic (MT80), ethanolic (MTE), and aqueous (MTW). In addition, the antioxidant, anti-inflammatory, antiproliferative and antibacterial potentials of the extracts were assessed. The mangosteen pericarp showed a composition with seven organic acids, three tocopherol isomers, four fatty acids and fifteen phenolic compounds. Regarding the extraction of phenolics, the MT80 was the most efficient (54 mg/g extract), followed by MTE (19.79 mg/g extract) and MTW (4.011 mg/g extract). All extracts showed antioxidant and antibacterial activities; however, MT80 and MTE extracts were more efficient than MTW. Only MTW did not show anti-inflammatory properties, whereas MTE and MT80 showed inhibitory activities towards tumor cell lines. Notwithstanding, MTE showed cytotoxicity towards normal cells. Our findings support the idea that the ripe mangosteen pericarp is a source of bioactive compounds, although their recovery is dependent on the extraction solvent. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-05-04T10:59:38Z 2023 2023-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10198/4158 |
url |
http://hdl.handle.net/10198/4158 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Albuquerque, Bianca R.; Dias, Maria Inês; Pinela, José; Calhelha, Ricardo C.; Pires, Tânia C.S.P.; Alves, Maria José; Corrêa, Rúbia C.G.; Ferreira, Isabel C.F.R.; Oliveira, M. Beatriz P. P.; Barros, Lillian (2023). Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp. Foods. eISSN 2304-8158. 12:5, p. 1-15 10.3390/foods12050994 2304-8158 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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