Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp

Detalhes bibliográficos
Autor(a) principal: Albuquerque, Bianca R.
Data de Publicação: 2011
Outros Autores: Dias, Maria Inês, Pinela, José, Calhelha, Ricardo C., Pires, Tânia C.S.P., Alves, Maria José, Corrêa, Rúbia C.G., Ferreira, Isabel C.F.R., Oliveira, Beatriz, Barros, Lillian
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10198/4158
Resumo: The industrial processing of mangosteen (Garcinia mangostana L.) generates high amounts of waste, as similar to 60% of the fruit is formed by an inedible pericarp. However, its pericarp has been explored as a source of xanthones; nevertheless, studies addressing the recovery of other chemical compounds from such biomass are still scarce. Hence, this study intended to elucidate the chemical composition of the mangosteen pericarp, including fat-soluble (tocopherols and fatty acids) and water-soluble (organic acids and phenolic compound non-xanthones) compounds present in the following extracts: hydroethanolic (MT80), ethanolic (MTE), and aqueous (MTW). In addition, the antioxidant, anti-inflammatory, antiproliferative and antibacterial potentials of the extracts were assessed. The mangosteen pericarp showed a composition with seven organic acids, three tocopherol isomers, four fatty acids and fifteen phenolic compounds. Regarding the extraction of phenolics, the MT80 was the most efficient (54 mg/g extract), followed by MTE (19.79 mg/g extract) and MTW (4.011 mg/g extract). All extracts showed antioxidant and antibacterial activities; however, MT80 and MTE extracts were more efficient than MTW. Only MTW did not show anti-inflammatory properties, whereas MTE and MT80 showed inhibitory activities towards tumor cell lines. Notwithstanding, MTE showed cytotoxicity towards normal cells. Our findings support the idea that the ripe mangosteen pericarp is a source of bioactive compounds, although their recovery is dependent on the extraction solvent.
id RCAP_dd23eef07ebf1c61895f3f4a278d8604
oai_identifier_str oai:bibliotecadigital.ipb.pt:10198/4158
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarpFood waste recoveryBioactive compoundsFlavonoidsAntiproliferative activityFood supplementThe industrial processing of mangosteen (Garcinia mangostana L.) generates high amounts of waste, as similar to 60% of the fruit is formed by an inedible pericarp. However, its pericarp has been explored as a source of xanthones; nevertheless, studies addressing the recovery of other chemical compounds from such biomass are still scarce. Hence, this study intended to elucidate the chemical composition of the mangosteen pericarp, including fat-soluble (tocopherols and fatty acids) and water-soluble (organic acids and phenolic compound non-xanthones) compounds present in the following extracts: hydroethanolic (MT80), ethanolic (MTE), and aqueous (MTW). In addition, the antioxidant, anti-inflammatory, antiproliferative and antibacterial potentials of the extracts were assessed. The mangosteen pericarp showed a composition with seven organic acids, three tocopherol isomers, four fatty acids and fifteen phenolic compounds. Regarding the extraction of phenolics, the MT80 was the most efficient (54 mg/g extract), followed by MTE (19.79 mg/g extract) and MTW (4.011 mg/g extract). All extracts showed antioxidant and antibacterial activities; however, MT80 and MTE extracts were more efficient than MTW. Only MTW did not show anti-inflammatory properties, whereas MTE and MT80 showed inhibitory activities towards tumor cell lines. Notwithstanding, MTE showed cytotoxicity towards normal cells. Our findings support the idea that the ripe mangosteen pericarp is a source of bioactive compounds, although their recovery is dependent on the extraction solvent.MDPIBiblioteca Digital do IPBAlbuquerque, Bianca R.Dias, Maria InêsPinela, JoséCalhelha, Ricardo C.Pires, Tânia C.S.P.Alves, Maria JoséCorrêa, Rúbia C.G.Ferreira, Isabel C.F.R.Oliveira, BeatrizBarros, Lillian2011-05-04T10:59:38Z20232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/4158engAlbuquerque, Bianca R.; Dias, Maria Inês; Pinela, José; Calhelha, Ricardo C.; Pires, Tânia C.S.P.; Alves, Maria José; Corrêa, Rúbia C.G.; Ferreira, Isabel C.F.R.; Oliveira, M. Beatriz P. P.; Barros, Lillian (2023). Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp. Foods. eISSN 2304-8158. 12:5, p. 1-1510.3390/foods120509942304-8158info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-07T01:17:51Zoai:bibliotecadigital.ipb.pt:10198/4158Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:56:42.046132Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp
title Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp
spellingShingle Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp
Albuquerque, Bianca R.
Food waste recovery
Bioactive compounds
Flavonoids
Antiproliferative activity
Food supplement
title_short Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp
title_full Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp
title_fullStr Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp
title_full_unstemmed Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp
title_sort Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp
author Albuquerque, Bianca R.
author_facet Albuquerque, Bianca R.
Dias, Maria Inês
Pinela, José
Calhelha, Ricardo C.
Pires, Tânia C.S.P.
Alves, Maria José
Corrêa, Rúbia C.G.
Ferreira, Isabel C.F.R.
Oliveira, Beatriz
Barros, Lillian
author_role author
author2 Dias, Maria Inês
Pinela, José
Calhelha, Ricardo C.
Pires, Tânia C.S.P.
Alves, Maria José
Corrêa, Rúbia C.G.
Ferreira, Isabel C.F.R.
Oliveira, Beatriz
Barros, Lillian
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.contributor.author.fl_str_mv Albuquerque, Bianca R.
Dias, Maria Inês
Pinela, José
Calhelha, Ricardo C.
Pires, Tânia C.S.P.
Alves, Maria José
Corrêa, Rúbia C.G.
Ferreira, Isabel C.F.R.
Oliveira, Beatriz
Barros, Lillian
dc.subject.por.fl_str_mv Food waste recovery
Bioactive compounds
Flavonoids
Antiproliferative activity
Food supplement
topic Food waste recovery
Bioactive compounds
Flavonoids
Antiproliferative activity
Food supplement
description The industrial processing of mangosteen (Garcinia mangostana L.) generates high amounts of waste, as similar to 60% of the fruit is formed by an inedible pericarp. However, its pericarp has been explored as a source of xanthones; nevertheless, studies addressing the recovery of other chemical compounds from such biomass are still scarce. Hence, this study intended to elucidate the chemical composition of the mangosteen pericarp, including fat-soluble (tocopherols and fatty acids) and water-soluble (organic acids and phenolic compound non-xanthones) compounds present in the following extracts: hydroethanolic (MT80), ethanolic (MTE), and aqueous (MTW). In addition, the antioxidant, anti-inflammatory, antiproliferative and antibacterial potentials of the extracts were assessed. The mangosteen pericarp showed a composition with seven organic acids, three tocopherol isomers, four fatty acids and fifteen phenolic compounds. Regarding the extraction of phenolics, the MT80 was the most efficient (54 mg/g extract), followed by MTE (19.79 mg/g extract) and MTW (4.011 mg/g extract). All extracts showed antioxidant and antibacterial activities; however, MT80 and MTE extracts were more efficient than MTW. Only MTW did not show anti-inflammatory properties, whereas MTE and MT80 showed inhibitory activities towards tumor cell lines. Notwithstanding, MTE showed cytotoxicity towards normal cells. Our findings support the idea that the ripe mangosteen pericarp is a source of bioactive compounds, although their recovery is dependent on the extraction solvent.
publishDate 2011
dc.date.none.fl_str_mv 2011-05-04T10:59:38Z
2023
2023-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10198/4158
url http://hdl.handle.net/10198/4158
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Albuquerque, Bianca R.; Dias, Maria Inês; Pinela, José; Calhelha, Ricardo C.; Pires, Tânia C.S.P.; Alves, Maria José; Corrêa, Rúbia C.G.; Ferreira, Isabel C.F.R.; Oliveira, M. Beatriz P. P.; Barros, Lillian (2023). Insights into the chemical composition and in vitro bioactive properties of mangosteen (Garcinia mangostana L.) pericarp. Foods. eISSN 2304-8158. 12:5, p. 1-15
10.3390/foods12050994
2304-8158
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799135176622604289