Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10362/136124 |
Resumo: | Funding: F Carvalho and E Fernandes acknowledge support from Fundação para a Ciência e a Tecnologia, I.P. (FCT), in the scope of the project UIDP/04378/2020 and UIDB/04378/2020 of the Research Unit on Applied Molecular Biosciences UCIBIO and the project LA/P/0140/2020 of the Associate Laboratory Institute for Health and Bioeconomy i4HB; FCT/MCTES through the project UIDB/50006/2020. J Conde acknowledges the European Research Council Starting Grant (ERC-StG-2019-848325). V M Costa acknowledges the grant SFRH/BHD/110001/2015, received by Portuguese national funds through Fundação para a Ciência e Tecnologia (FCT), IP, under the Norma Transitória DL57/2016/CP1334/CT0006. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019SDG 3 - Good Health and Well-beingFunding: F Carvalho and E Fernandes acknowledge support from Fundação para a Ciência e a Tecnologia, I.P. (FCT), in the scope of the project UIDP/04378/2020 and UIDB/04378/2020 of the Research Unit on Applied Molecular Biosciences UCIBIO and the project LA/P/0140/2020 of the Associate Laboratory Institute for Health and Bioeconomy i4HB; FCT/MCTES through the project UIDB/50006/2020. J Conde acknowledges the European Research Council Starting Grant (ERC-StG-2019-848325). V M Costa acknowledges the grant SFRH/BHD/110001/2015, received by Portuguese national funds through Fundação para a Ciência e Tecnologia (FCT), IP, under the Norma Transitória DL57/2016/CP1334/CT0006.BACKGROUND: Colorectal cancer is the third leading cause of cancer deaths worldwide. Given the recent increasing trends in colorectal cancer incidence globally, up-to-date information on the colorectal cancer burden could guide screening, early detection, and treatment strategies, and help effectively allocate resources. We examined the temporal patterns of the global, regional, and national burden of colorectal cancer and its risk factors in 204 countries and territories across the past three decades. METHODS: Estimates of incidence, mortality, and disability-adjusted life years (DALYs) for colorectal cancer were generated as a part of the Global Burden of Diseases, Injuries and Risk Factors Study (GBD) 2019 by age, sex, and geographical location for the period 1990-2019. Mortality estimates were produced using the cause of death ensemble model. We also calculated DALYs attributable to risk factors that had evidence of causation with colorectal cancer. FINDINGS: Globally, between 1990 and 2019, colorectal cancer incident cases more than doubled, from 842 098 (95% uncertainty interval [UI] 810 408-868 574) to 2·17 million (2·00-2·34), and deaths increased from 518 126 (493 682-537 877) to 1·09 million (1·02-1·15). The global age-standardised incidence rate increased from 22·2 (95% UI 21·3-23·0) per 100 000 to 26·7 (24·6-28·9) per 100 000, whereas the age-standardised mortality rate decreased from 14·3 (13·5-14·9) per 100 000 to 13·7 (12·6-14·5) per 100 000 and the age-standardised DALY rate decreased from 308·5 (294·7-320·7) per 100 000 to 295·5 (275·2-313·0) per 100 000 from 1990 through 2019. Taiwan (province of China; 62·0 [48·9-80·0] per 100 000), Monaco (60·7 [48·5-73·6] per 100 000), and Andorra (56·6 [42·8-71·9] per 100 000) had the highest age-standardised incidence rates, while Greenland (31·4 [26·0-37·1] per 100 000), Brunei (30·3 [26·6-34·1] per 100 000), and Hungary (28·6 [23·6-34·0] per 100 000) had the highest age-standardised mortality rates. From 1990 through 2019, a substantial rise in incidence rates was observed in younger adults (age <50 years), particularly in high Socio-demographic Index (SDI) countries. Globally, a diet low in milk (15·6%), smoking (13·3%), a diet low in calcium (12·9%), and alcohol use (9·9%) were the main contributors to colorectal cancer DALYs in 2019. INTERPRETATION: The increase in incidence rates in people younger than 50 years requires vigilance from researchers, clinicians, and policy makers and a possible reconsideration of screening guidelines. The fast-rising burden in low SDI and middle SDI countries in Asia and Africa calls for colorectal cancer prevention approaches, greater awareness, and cost-effective screening and therapeutic options in these regions. FUNDING: Bill & Melinda Gates Foundation.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNSharma, RajeshAbbasi-kangevari, MohsenAbd-rabu, RamiAbidi, HassanAbu-Gharbieh, EmanAcuna, Juan ManuelAdhikari, SangeetAdvani, Shailesh MAfzal, Muhammad SohailAghaie Meybodi, MohamadAhinkorah, Bright OpokuEl Sayed, ImanElhadi, MuhammedEnyew, Daniel BerhanieEyayu, TahirEzzeddini, RanaFakhradiyev, Ildar RavisovichFarooque, UmarFarrokhpour, HosseinFarzadfar, FarshadFatehizadeh, AliAhmad, SajjadFattahi, HamedFattahi, NimaFereidoonnezhad, MasoodFernandes, EduardaFetensa, GetahunFilip, IrinaFischer, FlorianForoutan, MasoudGaal, Peter AndrasGad, Mohamed MAhmadi, AliGallus, SilvanoGarg, TusharGetachew, TamiruGhamari, Seyyed-hadiGhashghaee, AhmadGhith, NerminGholamalizadeh, MaryamGholizadeh Navashenaq, JamshidGizaw, Abraham TamiratGlasbey, James CAhmadi, SepidehGolechha, MahaveerGoleij, PouyaGonfa, Kebebe BekeleGorini, GiuseppeGuha, AvirupGupta, SapnaGupta, Veer BalaGupta, Vivek KumarHaddadi, RasoolHafezi-nejad, NimaAhmed, HaroonHaj-mirzaian, ArvinHalwani, RabihHaque, ShafiulHariri, SanamHasaballah, Ahmed IHassanipour, SoheilHay, Simon IHerteliu, ClaudiuHolla, RameshHosseini, Mohammad-salarAhmed, Luai AHosseinzadeh, MehdiHostiuc, MihaelaHouseh, MowafaHuang, JunjieHumayun, AyeshaIavicoli, IvoIlesanmi, Olayinka StephenIlic, Irena MIlic, Milena DIslami, FarhadAhmed, Muktar BeshirIwagami, MasaoJahani, Mohammad AliJakovljevic, MihajloJavaheri, TaherehJayawardena, RanilJebai, RimeJha, Ravi PrakashJoo, TamasJoseph, NitinJoukar, FarahnazAl Hamad, HanadiJozwiak, Jacek JerzyKabir, AliKalhor, RohollahKamath, AshwinKapoor, NeetiKaraye, Ibraheem MKarimi, AmiraliKauppila, Joonas HKazemi, AsmaKeykhaei, MohammadAlahdab, FaresKhader, Yousef SalehKhajuria, HimanshuKhalilov, RovshanKhanali, JavadKhayamzadeh, MaryamKhodadost, MahmoudKim, HannaKim, Min SeoKisa, AdnanKisa, SezerAlanezi, Fahad MashhourKolahi, Ali-asgharKoohestani, Hamid RezaKopec, Jacek AKoteeswaran, RajasekaranKoyanagi, 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dc.title.none.fl_str_mv |
Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 |
title |
Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 |
spellingShingle |
Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 Sharma, Rajesh SDG 3 - Good Health and Well-being |
title_short |
Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 |
title_full |
Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 |
title_fullStr |
Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 |
title_full_unstemmed |
Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 |
title_sort |
Global, regional, and national burden of colorectal cancer and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 |
author |
Sharma, Rajesh |
author_facet |
Sharma, Rajesh Abbasi-kangevari, Mohsen Abd-rabu, Rami Abidi, Hassan Abu-Gharbieh, Eman Acuna, Juan Manuel Adhikari, Sangeet Advani, Shailesh M Afzal, Muhammad Sohail Aghaie Meybodi, Mohamad Ahinkorah, Bright Opoku El Sayed, Iman Elhadi, Muhammed Enyew, Daniel Berhanie Eyayu, Tahir Ezzeddini, Rana Fakhradiyev, Ildar Ravisovich Farooque, Umar Farrokhpour, Hossein Farzadfar, Farshad Fatehizadeh, Ali Ahmad, Sajjad Fattahi, Hamed Fattahi, Nima Fereidoonnezhad, Masood Fernandes, Eduarda Fetensa, Getahun Filip, Irina Fischer, Florian Foroutan, Masoud Gaal, Peter Andras Gad, Mohamed M Ahmadi, Ali Gallus, Silvano Garg, Tushar Getachew, Tamiru Ghamari, Seyyed-hadi Ghashghaee, Ahmad Ghith, Nermin Gholamalizadeh, Maryam Gholizadeh Navashenaq, Jamshid Gizaw, Abraham Tamirat Glasbey, James C Ahmadi, Sepideh Golechha, Mahaveer Goleij, Pouya Gonfa, Kebebe Bekele Gorini, Giuseppe Guha, Avirup Gupta, Sapna Gupta, Veer Bala Gupta, Vivek Kumar Haddadi, Rasool Hafezi-nejad, Nima Ahmed, Haroon Haj-mirzaian, Arvin Halwani, Rabih Haque, Shafiul Hariri, Sanam Hasaballah, Ahmed I Hassanipour, Soheil Hay, Simon I Herteliu, Claudiu Holla, Ramesh Hosseini, Mohammad-salar Ahmed, Luai A Hosseinzadeh, Mehdi Hostiuc, Mihaela Househ, Mowafa Huang, Junjie Humayun, Ayesha Iavicoli, Ivo Ilesanmi, Olayinka Stephen Ilic, Irena M Ilic, Milena D Islami, Farhad Ahmed, Muktar Beshir Iwagami, Masao Jahani, Mohammad Ali Jakovljevic, Mihajlo Javaheri, Tahereh Jayawardena, Ranil Jebai, Rime Jha, Ravi Prakash Joo, Tamas Joseph, Nitin Joukar, Farahnaz Al Hamad, Hanadi Jozwiak, Jacek Jerzy Kabir, Ali Kalhor, Rohollah Kamath, Ashwin Kapoor, Neeti Karaye, Ibraheem M Karimi, Amirali Kauppila, Joonas H Kazemi, Asma Keykhaei, Mohammad Alahdab, Fares Khader, Yousef Saleh Khajuria, Himanshu Khalilov, Rovshan Khanali, Javad Khayamzadeh, Maryam Khodadost, Mahmoud Kim, Hanna Kim, Min Seo Kisa, Adnan Kisa, Sezer Alanezi, Fahad Mashhour Kolahi, Ali-asghar Koohestani, Hamid Reza Kopec, Jacek A Koteeswaran, Rajasekaran Koyanagi, Ai Krishnamoorthy, Yuvaraj Kumar, G Anil Kumar, Manoj Kumar, Vivek La Vecchia, Carlo Alanzi, Turki M Lami, Faris Hasan Landires, Iván Ledda, Caterina Lee, Sang-woong Lee, Wei-chen Lee, Yeong Yeh Leong, Elvynna Li, Bingyu Lim, Stephen S Lobo, Stany W Alhalaiqa, Fadwa Alhalaiqa Naji Loureiro, Joana A Lunevicius, Raimundas Madadizadeh, Farzan Mahmoodpoor, Ata Majeed, Azeem Malekpour, Mohammad-reza Malekzadeh, Reza Malik, Ahmad Azam Mansour-ghanaei, Fariborz Mantovani, Lorenzo Giovanni Alimohamadi, Yousef Martorell, Miquel Masoudi, Sahar Mathur, Prashant Meena, Jitendra Kumar Mehrabi Nasab, Entezar Mendoza, Walter Mentis, Alexios-fotios A Mestrovic, Tomislav Miao Jonasson, Junmei Miazgowski, Bartosz Alipour, Vahid Miazgowski, Tomasz Mijena, Gelana Fekadu Worku Mirmoeeni, Seyyedmohammadsadeq Mirza-aghazadeh-attari, Mohammad Mirzaei, Hamed Misra, Sanjeev Mohammad, Karzan Abdulmuhsin Mohammadi, Esmaeil Mohammadi, Saeed Mohammadi, Seyyede Momeneh Aljunid, Syed Mohamed Mohammadian-hafshejani, Abdollah Mohammed, Shafiu Mohammed, Teroj Abdulrahman Moka, Nagabhishek Mokdad, Ali H Mokhtari, Zeinab Molokhia, Mariam Momtazmanesh, Sara Monasta, Lorenzo Moradi, Ghobad Alkhayyat, Motasem Moradzadeh, Rahmatollah Moraga, Paula Morgado-da-costa, Joana Mubarik, Sumaira Mulita, Francesk Naghavi, Mohsen Naimzada, Mukhammad David Nam, Hae Sung Natto, Zuhair S Nayak, Biswa Prakash Almustanyir, Sami Nazari, Javad Nazemalhosseini-mojarad, Ehsan Negoi, Ionut Nguyen, Cuong Tat Nguyen, Son Hoang Noor, Nurulamin M Noori, Maryam Noori, Seyyed Mohammad Ali Nuñez-samudio, Virginia Nzoputam, Chimezie Igwegbe Al-raddadi, Rajaa M Oancea, Bogdan Odukoya, Oluwakemi Ololade Oguntade, Ayodipupo Sikiru Okati-aliabad, Hassan Olagunju, Andrew T Olagunju, Tinuke O Ong, Sokking Ostroff, Samuel M Padron-monedero, Alicia Pakzad, Reza Alvand, Saba Pana, Adrian Pandey, Anamika Pashazadeh Kan, Fatemeh Patel, Urvish K Paudel, Uttam Pereira, Renato B Perumalsamy, Navaraj Pestell, Richard G Piracha, Zahra Zahid Pollok, Richard Charles G Alvis-guzman, Nelson Pourshams, Akram Pourtaheri, Naeimeh Prashant, Akila Rabiee, Mohammad Rabiee, Navid Radfar, Amir Rafiei, Sima Rahman, Mosiur Rahmani, Amir Masoud Rahmanian, Vahid Amini, Saeed Rajai, Nazanin Rajesh, Aashish Ramezani-doroh, Vajiheh Ramezanzadeh, Kiana Ranabhat, Kamal Rashedi, Sina Rashidi, Amirfarzan Rashidi, Mahsa Rashidi, Mohammad-mahdi Rastegar, Mandana Ancuceanu, Robert Rawaf, David Laith Rawaf, Salman Rawassizadeh, Reza Razeghinia, Mohammad Sadegh Renzaho, Andre M N Rezaei, Negar Rezaei, Nima Rezaei, Saeid Rezaeian, Mohsen Rezazadeh-khadem, Sahba Anoushiravani, Amir Roshandel, Gholamreza Saber-ayad, Maha Mohamed Saberzadeh-ardestani, Bahar Saddik, Basema Sadeghi, Hossein Saeed, Umar Sahebazzamani, Maryam Sahebkar, Amirhossein Salek Farrokhi, Amir Salimi, Amir Anoushirvani, Ali Arash Salimzadeh, Hamideh Samadi, Pouria Samaei, Mehrnoosh Samy, Abdallah M Sanabria, Juan Santric-milicevic, Milena M Saqib, Muhammad Arif Nadeem Sarveazad, Arash Sathian, Brijesh Satpathy, Maheswar Ansari-moghaddam, Alireza Schneider, Ione Jayce Ceola Šekerija, Mario Sepanlou, Sadaf G Seylani, Allen Sha, Feng Shafiee, Sayed Mohammad Shaghaghi, Zahra Shahabi, Saeed Shaker, Elaheh Sharifian, Maedeh Arabloo, Jalal Sharifi-rad, Javad Sheikhbahaei, Sara Shetty, Jeevan K Shirkoohi, Reza Shobeiri, Parnian Siddappa Malleshappa, Sudeep K Silva, Diego Augusto Santos Silva Julian, Guilherme Singh, Achintya Dinesh Singh, Jasvinder A Aryannejad, Armin Siraj, Md Shahjahan Sivandzadeh, Gholam Reza Skryabin, Valentin Yurievich Skryabina, Anna Aleksandrovna Socea, Bogdan Solmi, Marco Soltani-zangbar, Mohammad Sadegh Song, Suhang Szerencsés, Viktória Szócska, Miklós Asghari Jafarabadi, Mohammad Tabarés-seisdedos, Rafael Tabibian, Elnaz Taheri, Majid Taheriabkenar, Yasaman Taherkhani, Amir Talaat, Iman M Tan, Ker-kan Tbakhi, Abdelghani Tesfaye, Bekele Tiyuri, Amir Athari, Seyyed Shamsadin Tollosa, Daniel Nigusse Touvier, Mathilde Tran, Bach Xuan Tusa, Biruk Shalmeno Ullah, Irfan Ullah, Saif Vacante, Marco Valadan Tahbaz, Sahel Veroux, Massimiliano Vo, Bay Ausloos, Floriane Vos, Theo Wang, Cong Westerman, Ronny Woldemariam, Melat Yahyazadeh Jabbari, Seyed Hossein Yang, Lin Yazdanpanah, Fereshteh Yu, Chuanhua Yuce, Deniz Yunusa, Ismaeel Ausloos, Marcel Zadnik, Vesna Zahir, Mazyar Zare, Iman Zhang, Zhi-jiang Zoladl, Mohammad Awedew, Atalel Fentahun Awoke, Mamaru Ayenew Ayana, Tegegn Mulatu Azadnajafabad, Sina Azami, Hiva Azangou-khyavy, Mohammadreza Azari Jafari, Amirhossein Badiye, Ashish D Bagherieh, Sara Bahadory, Saeed Baig, Atif Amin Baker, Jennifer L Banach, Maciej Barrow, Amadou Berhie, Alemshet Yirga Besharat, Sima Bhagat, Devidas S Bhagavathula, Akshaya Srikanth Bhala, Neeraj Bhattacharyya, Krittika Bhojaraja, Vijayalakshmi S Bibi, Sadia Bijani, Ali Biondi, Antonio Bjørge, Tone Bodicha, Belay Boda Abule Braithwaite, Dejana Brenner, Hermann Calina, Daniela Cao, Chao Cao, Yin Carreras, Giulia Carvalho, Felix Cerin, Ester Chakinala, Raja Chandra Cho, William C S Chu, Dinh-toi Conde, Joao Costa, Vera Marisa Cruz-martins, Natália Dadras, Omid Dai, Xiaochen Dandona, Lalit Dandona, Rakhi Danielewicz, Anna Demeke, Feleke Mekonnen Demissie, Getu Debalkie Desai, Rupak Dhamnetiya, Deepak Dianatinasab, Mostafa Diaz, Daniel Didehdar, Mojtaba Doaei, Saeid Doan, Linh Phuong Dodangeh, Milad Eghbalian, Fatemeh Ejeta, Debela Debela Ekholuenetale, Michael Ekundayo, Temitope Cyrus |
author_role |
author |
author2 |
Abbasi-kangevari, Mohsen Abd-rabu, Rami Abidi, Hassan Abu-Gharbieh, Eman Acuna, Juan Manuel Adhikari, Sangeet Advani, Shailesh M Afzal, Muhammad Sohail Aghaie Meybodi, Mohamad Ahinkorah, Bright Opoku El Sayed, Iman Elhadi, Muhammed Enyew, Daniel Berhanie Eyayu, Tahir Ezzeddini, Rana Fakhradiyev, Ildar Ravisovich Farooque, Umar Farrokhpour, Hossein Farzadfar, Farshad Fatehizadeh, Ali Ahmad, Sajjad Fattahi, Hamed Fattahi, Nima Fereidoonnezhad, Masood Fernandes, Eduarda Fetensa, Getahun Filip, Irina Fischer, Florian Foroutan, Masoud Gaal, Peter Andras Gad, Mohamed M Ahmadi, Ali Gallus, Silvano Garg, Tushar Getachew, Tamiru Ghamari, Seyyed-hadi Ghashghaee, Ahmad Ghith, Nermin Gholamalizadeh, Maryam Gholizadeh Navashenaq, Jamshid Gizaw, Abraham Tamirat Glasbey, James C Ahmadi, Sepideh Golechha, Mahaveer Goleij, Pouya Gonfa, Kebebe Bekele Gorini, Giuseppe Guha, Avirup Gupta, Sapna Gupta, Veer Bala Gupta, Vivek Kumar Haddadi, Rasool Hafezi-nejad, Nima Ahmed, Haroon Haj-mirzaian, Arvin Halwani, Rabih Haque, Shafiul Hariri, Sanam Hasaballah, Ahmed I Hassanipour, Soheil Hay, Simon I Herteliu, Claudiu Holla, Ramesh Hosseini, Mohammad-salar Ahmed, Luai A Hosseinzadeh, Mehdi Hostiuc, Mihaela Househ, Mowafa Huang, Junjie Humayun, Ayesha Iavicoli, Ivo Ilesanmi, Olayinka Stephen Ilic, Irena M Ilic, Milena D Islami, Farhad Ahmed, Muktar Beshir Iwagami, Masao Jahani, Mohammad Ali Jakovljevic, Mihajlo Javaheri, Tahereh Jayawardena, Ranil Jebai, Rime Jha, Ravi Prakash Joo, Tamas Joseph, Nitin Joukar, Farahnaz Al Hamad, Hanadi Jozwiak, Jacek Jerzy Kabir, Ali Kalhor, Rohollah Kamath, Ashwin Kapoor, Neeti Karaye, Ibraheem M Karimi, Amirali Kauppila, Joonas H Kazemi, Asma Keykhaei, Mohammad Alahdab, Fares Khader, Yousef Saleh Khajuria, Himanshu Khalilov, Rovshan Khanali, Javad Khayamzadeh, Maryam Khodadost, Mahmoud Kim, Hanna Kim, Min Seo Kisa, Adnan Kisa, Sezer Alanezi, Fahad Mashhour Kolahi, Ali-asghar Koohestani, Hamid Reza Kopec, Jacek A Koteeswaran, Rajasekaran Koyanagi, Ai Krishnamoorthy, Yuvaraj Kumar, G Anil Kumar, Manoj Kumar, Vivek La Vecchia, Carlo Alanzi, Turki M Lami, Faris Hasan Landires, Iván Ledda, Caterina Lee, Sang-woong Lee, Wei-chen Lee, Yeong Yeh Leong, Elvynna Li, Bingyu Lim, Stephen S Lobo, Stany W Alhalaiqa, Fadwa Alhalaiqa Naji Loureiro, Joana A Lunevicius, Raimundas Madadizadeh, Farzan Mahmoodpoor, Ata Majeed, Azeem Malekpour, Mohammad-reza Malekzadeh, Reza Malik, Ahmad Azam Mansour-ghanaei, Fariborz Mantovani, Lorenzo Giovanni Alimohamadi, Yousef Martorell, Miquel Masoudi, Sahar Mathur, Prashant Meena, Jitendra Kumar Mehrabi Nasab, Entezar Mendoza, Walter Mentis, Alexios-fotios A Mestrovic, Tomislav Miao Jonasson, Junmei Miazgowski, Bartosz Alipour, Vahid Miazgowski, Tomasz Mijena, Gelana Fekadu Worku Mirmoeeni, Seyyedmohammadsadeq Mirza-aghazadeh-attari, Mohammad Mirzaei, Hamed Misra, Sanjeev Mohammad, Karzan Abdulmuhsin Mohammadi, Esmaeil Mohammadi, Saeed Mohammadi, Seyyede Momeneh Aljunid, Syed Mohamed Mohammadian-hafshejani, Abdollah Mohammed, Shafiu Mohammed, Teroj Abdulrahman Moka, Nagabhishek Mokdad, Ali H Mokhtari, Zeinab Molokhia, Mariam Momtazmanesh, Sara Monasta, Lorenzo Moradi, Ghobad Alkhayyat, Motasem Moradzadeh, Rahmatollah Moraga, Paula Morgado-da-costa, Joana Mubarik, Sumaira Mulita, Francesk Naghavi, Mohsen Naimzada, Mukhammad David Nam, Hae Sung Natto, Zuhair S Nayak, Biswa Prakash Almustanyir, Sami Nazari, Javad Nazemalhosseini-mojarad, Ehsan Negoi, Ionut Nguyen, Cuong Tat Nguyen, Son Hoang Noor, Nurulamin M Noori, Maryam Noori, Seyyed Mohammad Ali Nuñez-samudio, Virginia Nzoputam, Chimezie Igwegbe Al-raddadi, Rajaa M Oancea, Bogdan Odukoya, Oluwakemi Ololade Oguntade, Ayodipupo Sikiru Okati-aliabad, Hassan Olagunju, Andrew T Olagunju, Tinuke O Ong, Sokking Ostroff, Samuel M Padron-monedero, Alicia Pakzad, Reza Alvand, Saba Pana, Adrian Pandey, Anamika Pashazadeh Kan, Fatemeh Patel, Urvish K Paudel, Uttam Pereira, Renato B Perumalsamy, Navaraj Pestell, Richard G Piracha, Zahra Zahid Pollok, Richard Charles G Alvis-guzman, Nelson Pourshams, Akram Pourtaheri, Naeimeh Prashant, Akila Rabiee, Mohammad Rabiee, Navid Radfar, Amir Rafiei, Sima Rahman, Mosiur Rahmani, Amir Masoud Rahmanian, Vahid Amini, Saeed Rajai, Nazanin Rajesh, Aashish Ramezani-doroh, Vajiheh Ramezanzadeh, Kiana Ranabhat, Kamal Rashedi, Sina Rashidi, Amirfarzan Rashidi, Mahsa Rashidi, Mohammad-mahdi Rastegar, Mandana Ancuceanu, Robert Rawaf, David Laith Rawaf, Salman Rawassizadeh, Reza Razeghinia, Mohammad Sadegh Renzaho, Andre M N Rezaei, Negar Rezaei, Nima Rezaei, Saeid Rezaeian, Mohsen Rezazadeh-khadem, Sahba Anoushiravani, Amir Roshandel, Gholamreza Saber-ayad, Maha Mohamed Saberzadeh-ardestani, Bahar Saddik, Basema Sadeghi, Hossein Saeed, Umar Sahebazzamani, Maryam Sahebkar, Amirhossein Salek Farrokhi, Amir Salimi, Amir Anoushirvani, Ali Arash Salimzadeh, Hamideh Samadi, Pouria Samaei, Mehrnoosh Samy, Abdallah M Sanabria, Juan Santric-milicevic, Milena M Saqib, Muhammad Arif Nadeem Sarveazad, Arash Sathian, Brijesh Satpathy, Maheswar Ansari-moghaddam, Alireza Schneider, Ione Jayce Ceola Šekerija, Mario Sepanlou, Sadaf G Seylani, Allen Sha, Feng Shafiee, Sayed Mohammad Shaghaghi, Zahra Shahabi, Saeed Shaker, Elaheh Sharifian, Maedeh Arabloo, Jalal Sharifi-rad, Javad Sheikhbahaei, Sara Shetty, Jeevan K Shirkoohi, Reza Shobeiri, Parnian Siddappa Malleshappa, Sudeep K Silva, Diego Augusto Santos Silva Julian, Guilherme Singh, Achintya Dinesh Singh, Jasvinder A Aryannejad, Armin Siraj, Md Shahjahan Sivandzadeh, Gholam Reza Skryabin, Valentin Yurievich Skryabina, Anna Aleksandrovna Socea, Bogdan Solmi, Marco Soltani-zangbar, Mohammad Sadegh Song, Suhang Szerencsés, Viktória Szócska, Miklós Asghari Jafarabadi, Mohammad Tabarés-seisdedos, Rafael Tabibian, Elnaz Taheri, Majid Taheriabkenar, Yasaman Taherkhani, Amir Talaat, Iman M Tan, Ker-kan Tbakhi, Abdelghani Tesfaye, Bekele Tiyuri, Amir Athari, Seyyed Shamsadin Tollosa, Daniel Nigusse Touvier, Mathilde Tran, Bach Xuan Tusa, Biruk Shalmeno Ullah, Irfan Ullah, Saif Vacante, Marco Valadan Tahbaz, Sahel Veroux, Massimiliano Vo, Bay Ausloos, Floriane Vos, Theo Wang, Cong Westerman, Ronny Woldemariam, Melat Yahyazadeh Jabbari, Seyed Hossein Yang, Lin Yazdanpanah, Fereshteh Yu, Chuanhua Yuce, Deniz Yunusa, Ismaeel Ausloos, Marcel Zadnik, Vesna Zahir, Mazyar Zare, Iman Zhang, Zhi-jiang Zoladl, Mohammad Awedew, Atalel Fentahun Awoke, Mamaru Ayenew Ayana, Tegegn Mulatu Azadnajafabad, Sina Azami, Hiva Azangou-khyavy, Mohammadreza Azari Jafari, Amirhossein Badiye, Ashish D Bagherieh, Sara Bahadory, Saeed Baig, Atif Amin Baker, Jennifer L Banach, Maciej Barrow, Amadou Berhie, Alemshet Yirga Besharat, Sima Bhagat, Devidas S Bhagavathula, Akshaya Srikanth Bhala, Neeraj Bhattacharyya, Krittika Bhojaraja, Vijayalakshmi S Bibi, Sadia Bijani, Ali Biondi, Antonio Bjørge, Tone Bodicha, Belay Boda Abule Braithwaite, Dejana Brenner, Hermann Calina, Daniela Cao, Chao Cao, Yin Carreras, Giulia Carvalho, Felix Cerin, Ester Chakinala, Raja Chandra Cho, William C S Chu, Dinh-toi Conde, Joao Costa, Vera Marisa Cruz-martins, Natália Dadras, Omid Dai, Xiaochen Dandona, Lalit Dandona, Rakhi Danielewicz, Anna Demeke, Feleke Mekonnen Demissie, Getu Debalkie Desai, Rupak Dhamnetiya, Deepak Dianatinasab, Mostafa Diaz, Daniel Didehdar, Mojtaba Doaei, Saeid Doan, Linh Phuong Dodangeh, Milad Eghbalian, Fatemeh Ejeta, Debela Debela Ekholuenetale, Michael Ekundayo, Temitope Cyrus |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) RUN |
dc.contributor.author.fl_str_mv |
Sharma, Rajesh Abbasi-kangevari, Mohsen Abd-rabu, Rami Abidi, Hassan Abu-Gharbieh, Eman Acuna, Juan Manuel Adhikari, Sangeet Advani, Shailesh M Afzal, Muhammad Sohail Aghaie Meybodi, Mohamad Ahinkorah, Bright Opoku El Sayed, Iman Elhadi, Muhammed Enyew, Daniel Berhanie Eyayu, Tahir Ezzeddini, Rana Fakhradiyev, Ildar Ravisovich Farooque, Umar Farrokhpour, Hossein Farzadfar, Farshad Fatehizadeh, Ali Ahmad, Sajjad Fattahi, Hamed Fattahi, Nima Fereidoonnezhad, Masood Fernandes, Eduarda Fetensa, Getahun Filip, Irina Fischer, Florian Foroutan, Masoud Gaal, Peter Andras Gad, Mohamed M Ahmadi, Ali Gallus, Silvano Garg, Tushar Getachew, Tamiru Ghamari, Seyyed-hadi Ghashghaee, Ahmad Ghith, Nermin Gholamalizadeh, Maryam Gholizadeh Navashenaq, Jamshid Gizaw, Abraham Tamirat Glasbey, James C Ahmadi, Sepideh Golechha, Mahaveer Goleij, Pouya Gonfa, Kebebe Bekele Gorini, Giuseppe Guha, Avirup Gupta, Sapna Gupta, Veer Bala Gupta, Vivek Kumar Haddadi, Rasool Hafezi-nejad, Nima Ahmed, Haroon Haj-mirzaian, Arvin Halwani, Rabih Haque, Shafiul Hariri, Sanam Hasaballah, Ahmed I Hassanipour, Soheil Hay, Simon I Herteliu, Claudiu Holla, Ramesh Hosseini, Mohammad-salar Ahmed, Luai A Hosseinzadeh, Mehdi Hostiuc, Mihaela Househ, Mowafa Huang, Junjie Humayun, Ayesha Iavicoli, Ivo Ilesanmi, Olayinka Stephen Ilic, Irena M Ilic, Milena D Islami, Farhad Ahmed, Muktar Beshir Iwagami, Masao Jahani, Mohammad Ali Jakovljevic, Mihajlo Javaheri, Tahereh Jayawardena, Ranil Jebai, Rime Jha, Ravi Prakash Joo, Tamas Joseph, Nitin Joukar, Farahnaz Al Hamad, Hanadi Jozwiak, Jacek Jerzy Kabir, Ali Kalhor, Rohollah Kamath, Ashwin Kapoor, Neeti Karaye, Ibraheem M Karimi, Amirali Kauppila, Joonas H Kazemi, Asma Keykhaei, Mohammad Alahdab, Fares Khader, Yousef Saleh Khajuria, Himanshu Khalilov, Rovshan Khanali, Javad Khayamzadeh, Maryam Khodadost, Mahmoud Kim, Hanna Kim, Min Seo Kisa, Adnan Kisa, Sezer Alanezi, Fahad Mashhour Kolahi, Ali-asghar Koohestani, Hamid Reza Kopec, Jacek A Koteeswaran, Rajasekaran Koyanagi, Ai Krishnamoorthy, Yuvaraj Kumar, G Anil Kumar, Manoj Kumar, Vivek La Vecchia, Carlo Alanzi, Turki M Lami, Faris Hasan Landires, Iván Ledda, Caterina Lee, Sang-woong Lee, Wei-chen Lee, Yeong Yeh Leong, Elvynna Li, Bingyu Lim, Stephen S Lobo, Stany W Alhalaiqa, Fadwa Alhalaiqa Naji Loureiro, Joana A Lunevicius, Raimundas Madadizadeh, Farzan Mahmoodpoor, Ata Majeed, Azeem Malekpour, Mohammad-reza Malekzadeh, Reza Malik, Ahmad Azam Mansour-ghanaei, Fariborz Mantovani, Lorenzo Giovanni Alimohamadi, Yousef Martorell, Miquel Masoudi, Sahar Mathur, Prashant Meena, Jitendra Kumar Mehrabi Nasab, Entezar Mendoza, Walter Mentis, Alexios-fotios A Mestrovic, Tomislav Miao Jonasson, Junmei Miazgowski, Bartosz Alipour, Vahid Miazgowski, Tomasz Mijena, Gelana Fekadu Worku Mirmoeeni, Seyyedmohammadsadeq Mirza-aghazadeh-attari, Mohammad Mirzaei, Hamed Misra, Sanjeev Mohammad, Karzan Abdulmuhsin Mohammadi, Esmaeil Mohammadi, Saeed Mohammadi, Seyyede Momeneh Aljunid, Syed Mohamed Mohammadian-hafshejani, Abdollah Mohammed, Shafiu Mohammed, Teroj Abdulrahman Moka, Nagabhishek Mokdad, Ali H Mokhtari, Zeinab Molokhia, Mariam Momtazmanesh, Sara Monasta, Lorenzo Moradi, Ghobad Alkhayyat, Motasem Moradzadeh, Rahmatollah Moraga, Paula Morgado-da-costa, Joana Mubarik, Sumaira Mulita, Francesk Naghavi, Mohsen Naimzada, Mukhammad David Nam, Hae Sung Natto, Zuhair S Nayak, Biswa Prakash Almustanyir, Sami Nazari, Javad Nazemalhosseini-mojarad, Ehsan Negoi, Ionut Nguyen, Cuong Tat Nguyen, Son Hoang Noor, Nurulamin M Noori, Maryam Noori, Seyyed Mohammad Ali Nuñez-samudio, Virginia Nzoputam, Chimezie Igwegbe Al-raddadi, Rajaa M Oancea, Bogdan Odukoya, Oluwakemi Ololade Oguntade, Ayodipupo Sikiru Okati-aliabad, Hassan Olagunju, Andrew T Olagunju, Tinuke O Ong, Sokking Ostroff, Samuel M Padron-monedero, Alicia Pakzad, Reza Alvand, Saba Pana, Adrian Pandey, Anamika Pashazadeh Kan, Fatemeh Patel, Urvish K Paudel, Uttam Pereira, Renato B Perumalsamy, Navaraj Pestell, Richard G Piracha, Zahra Zahid Pollok, Richard Charles G Alvis-guzman, Nelson Pourshams, Akram Pourtaheri, Naeimeh Prashant, Akila Rabiee, Mohammad Rabiee, Navid Radfar, Amir Rafiei, Sima Rahman, Mosiur Rahmani, Amir Masoud Rahmanian, Vahid Amini, Saeed Rajai, Nazanin Rajesh, Aashish Ramezani-doroh, Vajiheh Ramezanzadeh, Kiana Ranabhat, Kamal Rashedi, Sina Rashidi, Amirfarzan Rashidi, Mahsa Rashidi, Mohammad-mahdi Rastegar, Mandana Ancuceanu, Robert Rawaf, David Laith Rawaf, Salman Rawassizadeh, Reza Razeghinia, Mohammad Sadegh Renzaho, Andre M N Rezaei, Negar Rezaei, Nima Rezaei, Saeid Rezaeian, Mohsen Rezazadeh-khadem, Sahba Anoushiravani, Amir Roshandel, Gholamreza Saber-ayad, Maha Mohamed Saberzadeh-ardestani, Bahar Saddik, Basema Sadeghi, Hossein Saeed, Umar Sahebazzamani, Maryam Sahebkar, Amirhossein Salek Farrokhi, Amir Salimi, Amir Anoushirvani, Ali Arash Salimzadeh, Hamideh Samadi, Pouria Samaei, Mehrnoosh Samy, Abdallah M Sanabria, Juan Santric-milicevic, Milena M Saqib, Muhammad Arif Nadeem Sarveazad, Arash Sathian, Brijesh Satpathy, Maheswar Ansari-moghaddam, Alireza Schneider, Ione Jayce Ceola Šekerija, Mario Sepanlou, Sadaf G Seylani, Allen Sha, Feng Shafiee, Sayed Mohammad Shaghaghi, Zahra Shahabi, Saeed Shaker, Elaheh Sharifian, Maedeh Arabloo, Jalal Sharifi-rad, Javad Sheikhbahaei, Sara Shetty, Jeevan K Shirkoohi, Reza Shobeiri, Parnian Siddappa Malleshappa, Sudeep K Silva, Diego Augusto Santos Silva Julian, Guilherme Singh, Achintya Dinesh Singh, Jasvinder A Aryannejad, Armin Siraj, Md Shahjahan Sivandzadeh, Gholam Reza Skryabin, Valentin Yurievich Skryabina, Anna Aleksandrovna Socea, Bogdan Solmi, Marco Soltani-zangbar, Mohammad Sadegh Song, Suhang Szerencsés, Viktória Szócska, Miklós Asghari Jafarabadi, Mohammad Tabarés-seisdedos, Rafael Tabibian, Elnaz Taheri, Majid Taheriabkenar, Yasaman Taherkhani, Amir Talaat, Iman M Tan, Ker-kan Tbakhi, Abdelghani Tesfaye, Bekele Tiyuri, Amir Athari, Seyyed Shamsadin Tollosa, Daniel Nigusse Touvier, Mathilde Tran, Bach Xuan Tusa, Biruk Shalmeno Ullah, Irfan Ullah, Saif Vacante, Marco Valadan Tahbaz, Sahel Veroux, Massimiliano Vo, Bay Ausloos, Floriane Vos, Theo Wang, Cong Westerman, Ronny Woldemariam, Melat Yahyazadeh Jabbari, Seyed Hossein Yang, Lin Yazdanpanah, Fereshteh Yu, Chuanhua Yuce, Deniz Yunusa, Ismaeel Ausloos, Marcel Zadnik, Vesna Zahir, Mazyar Zare, Iman Zhang, Zhi-jiang Zoladl, Mohammad Awedew, Atalel Fentahun Awoke, Mamaru Ayenew Ayana, Tegegn Mulatu Azadnajafabad, Sina Azami, Hiva Azangou-khyavy, Mohammadreza Azari Jafari, Amirhossein Badiye, Ashish D Bagherieh, Sara Bahadory, Saeed Baig, Atif Amin Baker, Jennifer L Banach, Maciej Barrow, Amadou Berhie, Alemshet Yirga Besharat, Sima Bhagat, Devidas S Bhagavathula, Akshaya Srikanth Bhala, Neeraj Bhattacharyya, Krittika Bhojaraja, Vijayalakshmi S Bibi, Sadia Bijani, Ali Biondi, Antonio Bjørge, Tone Bodicha, Belay Boda Abule Braithwaite, Dejana Brenner, Hermann Calina, Daniela Cao, Chao Cao, Yin Carreras, Giulia Carvalho, Felix Cerin, Ester Chakinala, Raja Chandra Cho, William C S Chu, Dinh-toi Conde, Joao Costa, Vera Marisa Cruz-martins, Natália Dadras, Omid Dai, Xiaochen Dandona, Lalit Dandona, Rakhi Danielewicz, Anna Demeke, Feleke Mekonnen Demissie, Getu Debalkie Desai, Rupak Dhamnetiya, Deepak Dianatinasab, Mostafa Diaz, Daniel Didehdar, Mojtaba Doaei, Saeid Doan, Linh Phuong Dodangeh, Milad Eghbalian, Fatemeh Ejeta, Debela Debela Ekholuenetale, Michael Ekundayo, Temitope Cyrus |
dc.subject.por.fl_str_mv |
SDG 3 - Good Health and Well-being |
topic |
SDG 3 - Good Health and Well-being |
description |
Funding: F Carvalho and E Fernandes acknowledge support from Fundação para a Ciência e a Tecnologia, I.P. (FCT), in the scope of the project UIDP/04378/2020 and UIDB/04378/2020 of the Research Unit on Applied Molecular Biosciences UCIBIO and the project LA/P/0140/2020 of the Associate Laboratory Institute for Health and Bioeconomy i4HB; FCT/MCTES through the project UIDB/50006/2020. J Conde acknowledges the European Research Council Starting Grant (ERC-StG-2019-848325). V M Costa acknowledges the grant SFRH/BHD/110001/2015, received by Portuguese national funds through Fundação para a Ciência e Tecnologia (FCT), IP, under the Norma Transitória DL57/2016/CP1334/CT0006. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-04-08T22:36:17Z 2022-07-22 2022-07-22T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/136124 |
url |
http://hdl.handle.net/10362/136124 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2468-1253 PURE: 43076310 https://doi.org/10.1016/S2468-1253(22)00044-9 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799138087023935488 |