Endothelial Progenitor Cells in Breast Cancer

Detalhes bibliográficos
Autor(a) principal: Botelho, M.C.
Data de Publicação: 2016
Outros Autores: Alves, H.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.18/3823
Resumo: Editorial
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spelling Endothelial Progenitor Cells in Breast CancerBreast CancerEndothelial Progenitor CellsAC133KDRVEGFEditorialRecent evidences demonstrated the importance of bone marrow derived Endothelial Progenitor Cells (EPC), in the contribution to postnatal physiological and pathological neovascularization, and in tumor growth and angiogenesis. These cells are recruited undifferentiated, in response to systemic or chemoatractive signals, such as Vascular Endothelial Growth Factor (VEGF), they lodge in the growing or lesioned tissue and differentiate into endothelial cells in response to local stimuli and cell-cell interactions. The extent and the significance of the EPCs contribution for the growing of most tumors, including those of the breast, are still not fully defined. We analyzed the peripheral blood of breast cancer patients and found that they have circulating EPCs. We also found an association between expression of AC133+Kdr+ and VEGF plasma levels in these patients. Strategies to impair the mobilization and incorporation of EPCs into breast tumors may contribute to halt the growth of these tumors.SM GroupRepositório Científico do Instituto Nacional de SaúdeBotelho, M.C.Alves, H.2016-05-25T12:14:15Z2016-01-232016-01-23T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.18/3823engInt J Immunother Cancer Res. 2016;2(1):1-2. Epub 2016 Jan 23.2455-8591info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-20T15:39:59ZPortal AgregadorONG
dc.title.none.fl_str_mv Endothelial Progenitor Cells in Breast Cancer
title Endothelial Progenitor Cells in Breast Cancer
spellingShingle Endothelial Progenitor Cells in Breast Cancer
Botelho, M.C.
Breast Cancer
Endothelial Progenitor Cells
AC133
KDR
VEGF
title_short Endothelial Progenitor Cells in Breast Cancer
title_full Endothelial Progenitor Cells in Breast Cancer
title_fullStr Endothelial Progenitor Cells in Breast Cancer
title_full_unstemmed Endothelial Progenitor Cells in Breast Cancer
title_sort Endothelial Progenitor Cells in Breast Cancer
author Botelho, M.C.
author_facet Botelho, M.C.
Alves, H.
author_role author
author2 Alves, H.
author2_role author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Nacional de Saúde
dc.contributor.author.fl_str_mv Botelho, M.C.
Alves, H.
dc.subject.por.fl_str_mv Breast Cancer
Endothelial Progenitor Cells
AC133
KDR
VEGF
topic Breast Cancer
Endothelial Progenitor Cells
AC133
KDR
VEGF
description Editorial
publishDate 2016
dc.date.none.fl_str_mv 2016-05-25T12:14:15Z
2016-01-23
2016-01-23T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.18/3823
url http://hdl.handle.net/10400.18/3823
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Int J Immunother Cancer Res. 2016;2(1):1-2. Epub 2016 Jan 23.
2455-8591
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv SM Group
publisher.none.fl_str_mv SM Group
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv
repository.mail.fl_str_mv
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