Evaluation of cardiovascular protective effect of different apple varieties - Correlation of response with composition

Detalhes bibliográficos
Autor(a) principal: Serra, A. T.
Data de Publicação: 2012
Outros Autores: Rocha, J., Sepodes, B., Matias, A. A., Feliciano, R. P., Carvalho, A. d., Bronze, M. R., Duarte, C. M. M., Figueira, M. E.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.26/5321
Resumo: NOTICE: this is the author’s version of a work that was accepted for publication in Food Chemistry. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Food Chemistry, Vol. 135, Issue 4, 2012. DOI http://dx.doi.org/10.1016/j.foodchem.2012.07.067
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spelling Evaluation of cardiovascular protective effect of different apple varieties - Correlation of response with compositionAnti-hypercholesterolemic effectApplesBravo de EsmolfeCardiovascular diseasePolyphenolsNOTICE: this is the author’s version of a work that was accepted for publication in Food Chemistry. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Food Chemistry, Vol. 135, Issue 4, 2012. DOI http://dx.doi.org/10.1016/j.foodchem.2012.07.067"Epidemiological evidence supports the concept that diets rich in fruits and vegetables promote health and attenuate or delay the onset of cardiovascular disease (CVD). In particular, a reduced risk of CVD has been associated with apple consumption, probably due to the cholesterol-lowering effect of the main bioactive compounds, namely fiber and polyphenols. In this work, the effect of diet supplementation with 20% of three Portuguese apple cultivars (Bravo de Esmolfe, Malápio Serra and Golden), containing distinct phenolic and fiber concentrations, on serum lipid profile and oxLDL of male Wistar rats fed a cholesterol-enriched diet (2%) was evaluated. After 30 days, only Bravo de Esmolfe apple was able to decrease significantly serum levels of triglycerides, total and LDL cholesterol concentrations (reductions of 27.2%, 21.0% and 20.4%, respectively, in relation to the cholesterol-enriched diet group, p<0.05) . The levels of oxLDL were also significantly improved with the consumption of this apple variety (reductions of 20.0% and 11.9%, in relation to the cholesterol-enriched diet group and control group, respectively, p>0.05) as well as with Malapio da Serra apple (reductions of 9.8% in relation to the cholesterol-enriched diet group, p<0.05). Correlation of the bioactive response with chemical composition showed that catechin, epicatechin, procyanidin B1 and -carotene are the major phytocompounds responsible for the cholesterol lowering ability of apples. The antioxidant potential may have also contributed to this beneficial effect."ElsevierRepositório ComumSerra, A. T.Rocha, J.Sepodes, B.Matias, A. A.Feliciano, R. P.Carvalho, A. d.Bronze, M. R.Duarte, C. M. M.Figueira, M. E.2014-01-15T11:43:50Z2012-12-01T00:00:00Z2012-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.26/5321engFood Chemistry Volume 135, Issue 4, 15 December 2012, Pages 2378–23860308-8146info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-10-06T14:51:25Zoai:comum.rcaap.pt:10400.26/5321Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:06:02.271474Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Evaluation of cardiovascular protective effect of different apple varieties - Correlation of response with composition
title Evaluation of cardiovascular protective effect of different apple varieties - Correlation of response with composition
spellingShingle Evaluation of cardiovascular protective effect of different apple varieties - Correlation of response with composition
Serra, A. T.
Anti-hypercholesterolemic effect
Apples
Bravo de Esmolfe
Cardiovascular disease
Polyphenols
title_short Evaluation of cardiovascular protective effect of different apple varieties - Correlation of response with composition
title_full Evaluation of cardiovascular protective effect of different apple varieties - Correlation of response with composition
title_fullStr Evaluation of cardiovascular protective effect of different apple varieties - Correlation of response with composition
title_full_unstemmed Evaluation of cardiovascular protective effect of different apple varieties - Correlation of response with composition
title_sort Evaluation of cardiovascular protective effect of different apple varieties - Correlation of response with composition
author Serra, A. T.
author_facet Serra, A. T.
Rocha, J.
Sepodes, B.
Matias, A. A.
Feliciano, R. P.
Carvalho, A. d.
Bronze, M. R.
Duarte, C. M. M.
Figueira, M. E.
author_role author
author2 Rocha, J.
Sepodes, B.
Matias, A. A.
Feliciano, R. P.
Carvalho, A. d.
Bronze, M. R.
Duarte, C. M. M.
Figueira, M. E.
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Comum
dc.contributor.author.fl_str_mv Serra, A. T.
Rocha, J.
Sepodes, B.
Matias, A. A.
Feliciano, R. P.
Carvalho, A. d.
Bronze, M. R.
Duarte, C. M. M.
Figueira, M. E.
dc.subject.por.fl_str_mv Anti-hypercholesterolemic effect
Apples
Bravo de Esmolfe
Cardiovascular disease
Polyphenols
topic Anti-hypercholesterolemic effect
Apples
Bravo de Esmolfe
Cardiovascular disease
Polyphenols
description NOTICE: this is the author’s version of a work that was accepted for publication in Food Chemistry. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Food Chemistry, Vol. 135, Issue 4, 2012. DOI http://dx.doi.org/10.1016/j.foodchem.2012.07.067
publishDate 2012
dc.date.none.fl_str_mv 2012-12-01T00:00:00Z
2012-12-01T00:00:00Z
2014-01-15T11:43:50Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.26/5321
url http://hdl.handle.net/10400.26/5321
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Food Chemistry Volume 135, Issue 4, 15 December 2012, Pages 2378–2386
0308-8146
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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