Scrofuloderma: A Diagnosis to Bear in Mind in the Western World

Detalhes bibliográficos
Autor(a) principal: Batista, Mariana
Data de Publicação: 2019
Outros Autores: Ferreira, Barbara, Cruz, Gonçalo, Figueiredo, Américo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10329
Resumo: The incidence of tuberculosis has been increasing worldwide. Contrarily, a recent decrease in Portugal has been reported. Cutaneous tuberculosis comprises a low percentage of all cases. We report a 70-year-old female with a 2-month-history of painful, nodular, suppurative lesions in the groin area, bilaterally. Previous history was remarkable for Human Immunodeficiency Virus infection and stage-IIIB cervical cancer. A skin biopsy, stained with periodic acid–Schiff and Fite’s stain, polymerase chain reaction on purulent discharge and mycobacterial culture of the skin were performed, leading to the diagnosis of scrofuloderma. Tuberculostatic therapy was initiated and complete response was observed. This case depicts an uncommon variant of tuberculosis, highlighting the need for awareness of the cutaneous variants of tuberculosis that, although rare, can still present in the clinic today.
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spelling Scrofuloderma: A Diagnosis to Bear in Mind in the Western WorldEscrofuloderma: Um Diagnóstico a Ponderar no Mundo OcidentalTuberculosisCutaneousTuberculose CutâneaThe incidence of tuberculosis has been increasing worldwide. Contrarily, a recent decrease in Portugal has been reported. Cutaneous tuberculosis comprises a low percentage of all cases. We report a 70-year-old female with a 2-month-history of painful, nodular, suppurative lesions in the groin area, bilaterally. Previous history was remarkable for Human Immunodeficiency Virus infection and stage-IIIB cervical cancer. A skin biopsy, stained with periodic acid–Schiff and Fite’s stain, polymerase chain reaction on purulent discharge and mycobacterial culture of the skin were performed, leading to the diagnosis of scrofuloderma. Tuberculostatic therapy was initiated and complete response was observed. This case depicts an uncommon variant of tuberculosis, highlighting the need for awareness of the cutaneous variants of tuberculosis that, although rare, can still present in the clinic today.A incidência de tuberculose tem vindo a aumentar globalmente. Em Portugal, porém, esta incidência diminuiu na última década. A tuberculose cutânea representa uma pequena percentagem de todos os casos. Apresenta-se o caso de uma mulher de 70 anos com nódulos supurativos da região inguinal bilateralmente, dolorosos, evoluindo há 2 meses. Como antecedentes relevantes, apresentava infeção por vírus da imunodeficiência humana e carcinoma do colo do útero, estadio IIIB. Foram realizadas biópsia cutânea (coloração pelo ácido periódico de Shiff e coloração de Fite), pesquisa de micobactérias por polymerase chain reaction e estudo microbiológico por cultura, tendo sido estabelecido o diagnóstico de escrofuloderma. Iniciou terapêutiva tuberculostática com resposta favorável. Este artigo realça a importância do reconhecimento das formas cutâneas de tuberculose e a necessidade de manter um elevado índice de suspeição, sobretudo em pacientes imunodeprimidos.Ordem dos Médicos2019-04-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfimage/jpegimage/jpegimage/jpegimage/jpegimage/jpegimage/jpegapplication/vnd.openxmlformats-officedocument.wordprocessingml.documentapplication/pdfapplication/mswordapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10329oai:ojs.www.actamedicaportuguesa.com:article/10329Acta Médica Portuguesa; Vol. 32 No. 4 (2019): April; 313-316Acta Médica Portuguesa; Vol. 32 N.º 4 (2019): Abril; 313-3161646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10329https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10329/5664https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10329/10037https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10329/10052https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10329/10053https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10329/10054https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10329/10055https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10329/10056https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10329/10081https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10329/10100https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10329/10142https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/10329/10476Direitos de Autor (c) 2019 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessBatista, MarianaFerreira, BarbaraCruz, GonçaloFigueiredo, Américo2022-12-20T11:05:56Zoai:ojs.www.actamedicaportuguesa.com:article/10329Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:19:52.225369Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Scrofuloderma: A Diagnosis to Bear in Mind in the Western World
Escrofuloderma: Um Diagnóstico a Ponderar no Mundo Ocidental
title Scrofuloderma: A Diagnosis to Bear in Mind in the Western World
spellingShingle Scrofuloderma: A Diagnosis to Bear in Mind in the Western World
Batista, Mariana
Tuberculosis
Cutaneous
Tuberculose Cutânea
title_short Scrofuloderma: A Diagnosis to Bear in Mind in the Western World
title_full Scrofuloderma: A Diagnosis to Bear in Mind in the Western World
title_fullStr Scrofuloderma: A Diagnosis to Bear in Mind in the Western World
title_full_unstemmed Scrofuloderma: A Diagnosis to Bear in Mind in the Western World
title_sort Scrofuloderma: A Diagnosis to Bear in Mind in the Western World
author Batista, Mariana
author_facet Batista, Mariana
Ferreira, Barbara
Cruz, Gonçalo
Figueiredo, Américo
author_role author
author2 Ferreira, Barbara
Cruz, Gonçalo
Figueiredo, Américo
author2_role author
author
author
dc.contributor.author.fl_str_mv Batista, Mariana
Ferreira, Barbara
Cruz, Gonçalo
Figueiredo, Américo
dc.subject.por.fl_str_mv Tuberculosis
Cutaneous
Tuberculose Cutânea
topic Tuberculosis
Cutaneous
Tuberculose Cutânea
description The incidence of tuberculosis has been increasing worldwide. Contrarily, a recent decrease in Portugal has been reported. Cutaneous tuberculosis comprises a low percentage of all cases. We report a 70-year-old female with a 2-month-history of painful, nodular, suppurative lesions in the groin area, bilaterally. Previous history was remarkable for Human Immunodeficiency Virus infection and stage-IIIB cervical cancer. A skin biopsy, stained with periodic acid–Schiff and Fite’s stain, polymerase chain reaction on purulent discharge and mycobacterial culture of the skin were performed, leading to the diagnosis of scrofuloderma. Tuberculostatic therapy was initiated and complete response was observed. This case depicts an uncommon variant of tuberculosis, highlighting the need for awareness of the cutaneous variants of tuberculosis that, although rare, can still present in the clinic today.
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 32 No. 4 (2019): April; 313-316
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