Morphology, topography, and optics of the orthokeratology cornea

Detalhes bibliográficos
Autor(a) principal: Ribeiro, Miguel António Faria
Data de Publicação: 2016
Outros Autores: Navarro, Rafael, López-Gil, Norberto, González-Méijome, José Manuel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/44049
Resumo: The goal of this work was to objectively characterize the external morphology, topography, and optics of the cornea after orthokeratology (ortho-k). A number of 24 patients between the ages of 17 and 30 years (median ¼ 24 years) were fitted with Corneal Refractive Therapy® contact lenses to correct myopia between −2.00 and −5.00 diopters (D) (median ¼ −3.41 D). A classification algorithm was applied to conduct an automatic segmentation based on the mean local curvature. As a result, three zones (optical zone, transition zone, and peripheral zone) were delimited. Topographical analysis was provided through global and zonal fit to a general ellipsoid. Ray trace on partially customized eye models provided wave aberrations and retinal image quality. Monozone topographic description of the ortho-k cornea loses accuracy when compared with zonal description. Primary (C0 4) and secondary (C0 6) spherical aberration (SA) coefficients for a 5-mm pupil increased 3.68 and 19 times, respectively, after the treatments. The OZ area showed a strong correlation with C0 4 (r ¼ −0.49, p < 0.05) and a very strong correlation with C0 6 (r ¼ 0.78, p < 0.01). The OZ, as well as the TZ, areas did not correlate with baseline refraction. The increase in the eye’s positive SA after ortho-k is the major factor responsible for the decreased retinal optical quality of the unaccommodated eye
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spelling Morphology, topography, and optics of the orthokeratology corneaOrthokeratologyCorneal refractive therapySpherical aberrationOcular aberrationsAccommodationMyopiaMyopia controlContrast sensitivity functionAccommodative lagScience & TechnologyThe goal of this work was to objectively characterize the external morphology, topography, and optics of the cornea after orthokeratology (ortho-k). A number of 24 patients between the ages of 17 and 30 years (median ¼ 24 years) were fitted with Corneal Refractive Therapy® contact lenses to correct myopia between −2.00 and −5.00 diopters (D) (median ¼ −3.41 D). A classification algorithm was applied to conduct an automatic segmentation based on the mean local curvature. As a result, three zones (optical zone, transition zone, and peripheral zone) were delimited. Topographical analysis was provided through global and zonal fit to a general ellipsoid. Ray trace on partially customized eye models provided wave aberrations and retinal image quality. Monozone topographic description of the ortho-k cornea loses accuracy when compared with zonal description. Primary (C0 4) and secondary (C0 6) spherical aberration (SA) coefficients for a 5-mm pupil increased 3.68 and 19 times, respectively, after the treatments. The OZ area showed a strong correlation with C0 4 (r ¼ −0.49, p < 0.05) and a very strong correlation with C0 6 (r ¼ 0.78, p < 0.01). The OZ, as well as the TZ, areas did not correlate with baseline refraction. The increase in the eye’s positive SA after ortho-k is the major factor responsible for the decreased retinal optical quality of the unaccommodated eyeThis work was funded in part by European Fund for Regional Development (FEDER) through the COMPETE Program and by the Portuguese Foundation for Science and Technology (FCT). FCT provided financial support in the framework of projects PTDC/SAU-BEB/098391/2008, PTDC/SAU-BEB/ 098392/2008 and the Strategic Project PEST-C/FIS/UI607/ 2011. The authors have no proprietary interest in the methods and devices described in this manuscript.Society of Photo Optical Instrumentation EngineersUniversidade do MinhoRibeiro, Miguel António FariaNavarro, RafaelLópez-Gil, NorbertoGonzález-Méijome, José Manuel20162016-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/44049engFaria-Ribeiro, M., Belsue, R. N., Lopez-Gil, N., & Gonzalez-Méijome, J. M. (2016). Morphology, topography, and optics of the orthokeratology cornea. Journal of Biomedical Optics, 21(7). doi: 10.1117/1.jbo.21.7.0750111083-366810.1117/1.JBO.21.7.07501127435895info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:18:45Zoai:repositorium.sdum.uminho.pt:1822/44049Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:11:35.657353Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Morphology, topography, and optics of the orthokeratology cornea
title Morphology, topography, and optics of the orthokeratology cornea
spellingShingle Morphology, topography, and optics of the orthokeratology cornea
Ribeiro, Miguel António Faria
Orthokeratology
Corneal refractive therapy
Spherical aberration
Ocular aberrations
Accommodation
Myopia
Myopia control
Contrast sensitivity function
Accommodative lag
Science & Technology
title_short Morphology, topography, and optics of the orthokeratology cornea
title_full Morphology, topography, and optics of the orthokeratology cornea
title_fullStr Morphology, topography, and optics of the orthokeratology cornea
title_full_unstemmed Morphology, topography, and optics of the orthokeratology cornea
title_sort Morphology, topography, and optics of the orthokeratology cornea
author Ribeiro, Miguel António Faria
author_facet Ribeiro, Miguel António Faria
Navarro, Rafael
López-Gil, Norberto
González-Méijome, José Manuel
author_role author
author2 Navarro, Rafael
López-Gil, Norberto
González-Méijome, José Manuel
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Ribeiro, Miguel António Faria
Navarro, Rafael
López-Gil, Norberto
González-Méijome, José Manuel
dc.subject.por.fl_str_mv Orthokeratology
Corneal refractive therapy
Spherical aberration
Ocular aberrations
Accommodation
Myopia
Myopia control
Contrast sensitivity function
Accommodative lag
Science & Technology
topic Orthokeratology
Corneal refractive therapy
Spherical aberration
Ocular aberrations
Accommodation
Myopia
Myopia control
Contrast sensitivity function
Accommodative lag
Science & Technology
description The goal of this work was to objectively characterize the external morphology, topography, and optics of the cornea after orthokeratology (ortho-k). A number of 24 patients between the ages of 17 and 30 years (median ¼ 24 years) were fitted with Corneal Refractive Therapy® contact lenses to correct myopia between −2.00 and −5.00 diopters (D) (median ¼ −3.41 D). A classification algorithm was applied to conduct an automatic segmentation based on the mean local curvature. As a result, three zones (optical zone, transition zone, and peripheral zone) were delimited. Topographical analysis was provided through global and zonal fit to a general ellipsoid. Ray trace on partially customized eye models provided wave aberrations and retinal image quality. Monozone topographic description of the ortho-k cornea loses accuracy when compared with zonal description. Primary (C0 4) and secondary (C0 6) spherical aberration (SA) coefficients for a 5-mm pupil increased 3.68 and 19 times, respectively, after the treatments. The OZ area showed a strong correlation with C0 4 (r ¼ −0.49, p < 0.05) and a very strong correlation with C0 6 (r ¼ 0.78, p < 0.01). The OZ, as well as the TZ, areas did not correlate with baseline refraction. The increase in the eye’s positive SA after ortho-k is the major factor responsible for the decreased retinal optical quality of the unaccommodated eye
publishDate 2016
dc.date.none.fl_str_mv 2016
2016-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/44049
url http://hdl.handle.net/1822/44049
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Faria-Ribeiro, M., Belsue, R. N., Lopez-Gil, N., & Gonzalez-Méijome, J. M. (2016). Morphology, topography, and optics of the orthokeratology cornea. Journal of Biomedical Optics, 21(7). doi: 10.1117/1.jbo.21.7.075011
1083-3668
10.1117/1.JBO.21.7.075011
27435895
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Society of Photo Optical Instrumentation Engineers
publisher.none.fl_str_mv Society of Photo Optical Instrumentation Engineers
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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