Histogram-based DNA analysis for the visualization of chromosome, genome and species information

Detalhes bibliográficos
Autor(a) principal: Costa, António Cardoso
Data de Publicação: 2011
Outros Autores: Machado, J. A. Tenreiro, Quelhas, Dulce
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.22/1434
Resumo: We describe a novel approach to explore DNA nucleotide sequence data, aiming to produce high-level categorical and structural information about the underlying chromosomes, genomes and species. The article starts by analyzing chromosomal data through histograms using fixed length DNA sequences. After creating the DNA-related histograms, a correlation between pairs of histograms is computed, producing a global correlation matrix. These data are then used as input to several data processing methods for information extraction and tabular/graphical output generation. A set of 18 species is processed and the extensive results reveal that the proposed method is able to generate significant and diversified outputs, in good accordance with current scientific knowledge in domains such as genomics and phylogenetics.
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spelling Histogram-based DNA analysis for the visualization of chromosome, genome and species informationDNAChromosomeHistogramAnalysisPhylogeneticsVisualizationWe describe a novel approach to explore DNA nucleotide sequence data, aiming to produce high-level categorical and structural information about the underlying chromosomes, genomes and species. The article starts by analyzing chromosomal data through histograms using fixed length DNA sequences. After creating the DNA-related histograms, a correlation between pairs of histograms is computed, producing a global correlation matrix. These data are then used as input to several data processing methods for information extraction and tabular/graphical output generation. A set of 18 species is processed and the extensive results reveal that the proposed method is able to generate significant and diversified outputs, in good accordance with current scientific knowledge in domains such as genomics and phylogenetics.Oxford University PressRepositório Científico do Instituto Politécnico do PortoCosta, António CardosoMachado, J. A. TenreiroQuelhas, Dulce2013-04-19T15:35:47Z20112011-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/1434eng1367-480310.1093/bioinformatics/btr131info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-13T12:40:43Zoai:recipp.ipp.pt:10400.22/1434Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:22:32.741872Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Histogram-based DNA analysis for the visualization of chromosome, genome and species information
title Histogram-based DNA analysis for the visualization of chromosome, genome and species information
spellingShingle Histogram-based DNA analysis for the visualization of chromosome, genome and species information
Costa, António Cardoso
DNA
Chromosome
Histogram
Analysis
Phylogenetics
Visualization
title_short Histogram-based DNA analysis for the visualization of chromosome, genome and species information
title_full Histogram-based DNA analysis for the visualization of chromosome, genome and species information
title_fullStr Histogram-based DNA analysis for the visualization of chromosome, genome and species information
title_full_unstemmed Histogram-based DNA analysis for the visualization of chromosome, genome and species information
title_sort Histogram-based DNA analysis for the visualization of chromosome, genome and species information
author Costa, António Cardoso
author_facet Costa, António Cardoso
Machado, J. A. Tenreiro
Quelhas, Dulce
author_role author
author2 Machado, J. A. Tenreiro
Quelhas, Dulce
author2_role author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Politécnico do Porto
dc.contributor.author.fl_str_mv Costa, António Cardoso
Machado, J. A. Tenreiro
Quelhas, Dulce
dc.subject.por.fl_str_mv DNA
Chromosome
Histogram
Analysis
Phylogenetics
Visualization
topic DNA
Chromosome
Histogram
Analysis
Phylogenetics
Visualization
description We describe a novel approach to explore DNA nucleotide sequence data, aiming to produce high-level categorical and structural information about the underlying chromosomes, genomes and species. The article starts by analyzing chromosomal data through histograms using fixed length DNA sequences. After creating the DNA-related histograms, a correlation between pairs of histograms is computed, producing a global correlation matrix. These data are then used as input to several data processing methods for information extraction and tabular/graphical output generation. A set of 18 species is processed and the extensive results reveal that the proposed method is able to generate significant and diversified outputs, in good accordance with current scientific knowledge in domains such as genomics and phylogenetics.
publishDate 2011
dc.date.none.fl_str_mv 2011
2011-01-01T00:00:00Z
2013-04-19T15:35:47Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.22/1434
url http://hdl.handle.net/10400.22/1434
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1367-4803
10.1093/bioinformatics/btr131
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Oxford University Press
publisher.none.fl_str_mv Oxford University Press
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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