Enzymatic activity mastered by altering metal coordination spheres

Detalhes bibliográficos
Autor(a) principal: Moura, Isabel
Data de Publicação: 2008
Outros Autores: Moura, José J. G., Pauleta, Sofia R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/8696
Resumo: J Biol Inorg Chem (2008) 13:1185–1195 DOI 10.1007/s00775-008-0414-3
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spelling Enzymatic activity mastered by altering metal coordination spheresEnzyme activationActive site coordinationHemeCopper and non-heme proteinsJ Biol Inorg Chem (2008) 13:1185–1195 DOI 10.1007/s00775-008-0414-3Metalloenzymes control enzymatic activity by changing the characteristics of the metal centers where catalysis takes place. The conversion between inactive and active states can be tuned by altering the coordination number of the metal site, and in some cases by an associated conformational change. These processes will be illustrated using heme proteins (cytochrome c nitrite reductase, cytochrome c peroxidase and cytochrome cd1 nitrite reductase), non-heme proteins (superoxide reductase and [NiFe]-hydrogenase), and copper proteins (nitrite and nitrous oxide reductases) as examples. These examples catalyze electron transfer reactions that include atom transfer, abstraction and insertion.SpringerRUNMoura, IsabelMoura, José J. G.Pauleta, Sofia R.2013-02-05T15:17:48Z20082008-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/8696eng0949-8257info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T03:41:34Zoai:run.unl.pt:10362/8696Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:18:22.842454Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Enzymatic activity mastered by altering metal coordination spheres
title Enzymatic activity mastered by altering metal coordination spheres
spellingShingle Enzymatic activity mastered by altering metal coordination spheres
Moura, Isabel
Enzyme activation
Active site coordination
Heme
Copper and non-heme proteins
title_short Enzymatic activity mastered by altering metal coordination spheres
title_full Enzymatic activity mastered by altering metal coordination spheres
title_fullStr Enzymatic activity mastered by altering metal coordination spheres
title_full_unstemmed Enzymatic activity mastered by altering metal coordination spheres
title_sort Enzymatic activity mastered by altering metal coordination spheres
author Moura, Isabel
author_facet Moura, Isabel
Moura, José J. G.
Pauleta, Sofia R.
author_role author
author2 Moura, José J. G.
Pauleta, Sofia R.
author2_role author
author
dc.contributor.none.fl_str_mv RUN
dc.contributor.author.fl_str_mv Moura, Isabel
Moura, José J. G.
Pauleta, Sofia R.
dc.subject.por.fl_str_mv Enzyme activation
Active site coordination
Heme
Copper and non-heme proteins
topic Enzyme activation
Active site coordination
Heme
Copper and non-heme proteins
description J Biol Inorg Chem (2008) 13:1185–1195 DOI 10.1007/s00775-008-0414-3
publishDate 2008
dc.date.none.fl_str_mv 2008
2008-01-01T00:00:00Z
2013-02-05T15:17:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/8696
url http://hdl.handle.net/10362/8696
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0949-8257
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eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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