A rare presentation of COVID-19 in a ten-year-old girl

Detalhes bibliográficos
Autor(a) principal: Pereira, Ana Cecília
Data de Publicação: 2022
Outros Autores: Machado, Sara, Oliveira, Susana, Macedo, Liliana, Loureiro, Marília, Marques, Laura, Sarmento, Alzira, Oliveira, Raquel
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.25753/BirthGrowthMJ.v31.i3.22180
Resumo: Multisystem inflammatory syndrome in children (MIS-C) is a severe and rare manifestation of SARS-CoV-2 infection. A 10-year-old-girl without epidemiological context of COVID-19 presented with fever, headache, and vomiting with two days of evolution. She was hemodynamically stable. Laboratory tests showed lymphopenia, mild thrombocytopenia, and positive C-reactive protein. Reverse transcription polymerase chain reaction (RT-PCR) for SARS-CoV-2 was negative. On the third day, she presented with worsening symptoms and non-pruriginous, non-petechial rash, with also worsening inflammatory parameters on laboratory assessment. The girl was admitted, and RT-PCR for SARS-CoV-2 was repeated, with positive result. On the fourth day, the patient was hypotensive, lethargic, and showed delayed capillary refill time, swelling and erythema of the palpebrae and nose, bilateral non-purulent conjunctivitis, reddened and cracked lips, strawberry tongue, and inflammation of mucous membranes. Multiorgan dysfunction developed, and she required admission to the Intensive Care Unit. MIS-C is a severe and potentially fatal syndro me, which clinicians should be aware of in the present pandemic setting. Close cardiac follow-up is recommended.
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spelling A rare presentation of COVID-19 in a ten-year-old girlUma rara apresentação de COVID-19 numa criança de dez anosCase ReportsMultisystem inflammatory syndrome in children (MIS-C) is a severe and rare manifestation of SARS-CoV-2 infection. A 10-year-old-girl without epidemiological context of COVID-19 presented with fever, headache, and vomiting with two days of evolution. She was hemodynamically stable. Laboratory tests showed lymphopenia, mild thrombocytopenia, and positive C-reactive protein. Reverse transcription polymerase chain reaction (RT-PCR) for SARS-CoV-2 was negative. On the third day, she presented with worsening symptoms and non-pruriginous, non-petechial rash, with also worsening inflammatory parameters on laboratory assessment. The girl was admitted, and RT-PCR for SARS-CoV-2 was repeated, with positive result. On the fourth day, the patient was hypotensive, lethargic, and showed delayed capillary refill time, swelling and erythema of the palpebrae and nose, bilateral non-purulent conjunctivitis, reddened and cracked lips, strawberry tongue, and inflammation of mucous membranes. Multiorgan dysfunction developed, and she required admission to the Intensive Care Unit. MIS-C is a severe and potentially fatal syndro me, which clinicians should be aware of in the present pandemic setting. Close cardiac follow-up is recommended.A síndrome inflamatória multissistémica pediátrica (SIM-P) é uma manifestação rara e grave de infeção por SARS-CoV-2. Uma criança de 10 anos de idade, do sexo feminino, sem contexto epidemiológico de COVID-19, apresentou-se com febre, cefaleias e vómitos com dois dias de evolução. Estava hemodinamicamente estável. Analiticamente, apresentava linfopenia, trombocitopenia ligeira e proteína C reativa positiva, com reação em cadeia da polimerase (PCR) para SARS-CoV-2 negativa. No terceiro dia, foi novamente observada por agravamento dos sintomas e exantema não petequial e não pruriginoso de novo, com agravamento laboratorial dos parâmetros inflamatórios. A PCR para SARS-CoV-2 foi positiva. No quarto dia, aquando do internamento, apresentava-se hipotensa e letárgica, com tempo de perfusão capilar aumentado, pálpebras e nariz eritematosos e edemaciados, conjuntivite não purulenta bilateral, lábios avermelhados e gretados, língua de framboesa e inflamação das membranas mucosas. Desenvolveu disfunção multiorgânica e foi admitida na Unidade de Cuidados Intensivos. A SIM-P é uma condição grave e potencialmente fatal, para a qual os clínicos devem estar alerta no atual contexto pandémico. É recomendada vigilância cardíaca rigorosa e regular.Centro Hospitalar Universitário do Porto2022-10-19info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.25753/BirthGrowthMJ.v31.i3.22180eng2183-9417Pereira, Ana CecíliaMachado, SaraOliveira, SusanaMacedo, LilianaLoureiro, MaríliaMarques, LauraSarmento, AlziraOliveira, Raquelinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-10-20T17:00:18Zoai:ojs.revistas.rcaap.pt:article/22180Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:13:20.789700Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv A rare presentation of COVID-19 in a ten-year-old girl
Uma rara apresentação de COVID-19 numa criança de dez anos
title A rare presentation of COVID-19 in a ten-year-old girl
spellingShingle A rare presentation of COVID-19 in a ten-year-old girl
Pereira, Ana Cecília
Case Reports
title_short A rare presentation of COVID-19 in a ten-year-old girl
title_full A rare presentation of COVID-19 in a ten-year-old girl
title_fullStr A rare presentation of COVID-19 in a ten-year-old girl
title_full_unstemmed A rare presentation of COVID-19 in a ten-year-old girl
title_sort A rare presentation of COVID-19 in a ten-year-old girl
author Pereira, Ana Cecília
author_facet Pereira, Ana Cecília
Machado, Sara
Oliveira, Susana
Macedo, Liliana
Loureiro, Marília
Marques, Laura
Sarmento, Alzira
Oliveira, Raquel
author_role author
author2 Machado, Sara
Oliveira, Susana
Macedo, Liliana
Loureiro, Marília
Marques, Laura
Sarmento, Alzira
Oliveira, Raquel
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Pereira, Ana Cecília
Machado, Sara
Oliveira, Susana
Macedo, Liliana
Loureiro, Marília
Marques, Laura
Sarmento, Alzira
Oliveira, Raquel
dc.subject.por.fl_str_mv Case Reports
topic Case Reports
description Multisystem inflammatory syndrome in children (MIS-C) is a severe and rare manifestation of SARS-CoV-2 infection. A 10-year-old-girl without epidemiological context of COVID-19 presented with fever, headache, and vomiting with two days of evolution. She was hemodynamically stable. Laboratory tests showed lymphopenia, mild thrombocytopenia, and positive C-reactive protein. Reverse transcription polymerase chain reaction (RT-PCR) for SARS-CoV-2 was negative. On the third day, she presented with worsening symptoms and non-pruriginous, non-petechial rash, with also worsening inflammatory parameters on laboratory assessment. The girl was admitted, and RT-PCR for SARS-CoV-2 was repeated, with positive result. On the fourth day, the patient was hypotensive, lethargic, and showed delayed capillary refill time, swelling and erythema of the palpebrae and nose, bilateral non-purulent conjunctivitis, reddened and cracked lips, strawberry tongue, and inflammation of mucous membranes. Multiorgan dysfunction developed, and she required admission to the Intensive Care Unit. MIS-C is a severe and potentially fatal syndro me, which clinicians should be aware of in the present pandemic setting. Close cardiac follow-up is recommended.
publishDate 2022
dc.date.none.fl_str_mv 2022-10-19
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv https://doi.org/10.25753/BirthGrowthMJ.v31.i3.22180
url https://doi.org/10.25753/BirthGrowthMJ.v31.i3.22180
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2183-9417
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dc.publisher.none.fl_str_mv Centro Hospitalar Universitário do Porto
publisher.none.fl_str_mv Centro Hospitalar Universitário do Porto
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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