Treatment of Venous Ulcers with Cronocol® implants – analysis of 10 cases
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://revista.spcir.com/index.php/spcir/article/view/42 |
Resumo: | Chronic venous insufficiency (CVI) of lower limbs is a health problem with a clear negative social impact in Portugal and worldwide. Venous ulcer is a major reason for work absenteeism. Its physiopathology is not well known, has a natural history of healing and recurrence, and a difficult healing process that is time and money consuming for health care facilities. The goal was to clinically 10 pa- tients with chronic venous ulcer, painful on the inclusion date and resistant to other treatments, without other associated pathologies, treated with Cronocol® implants. Three parameters were evaluated: pain, treatment continuity, cicatrisation. As outpatients, they had the implants applied on a weekly basis, dry gauze applied over them and elastic bandage of the leg. Data of the evolution with other treatments before Cronocol®, always including elastic compression, were used as control group. In the first ten patients (aged from 57 to 82) there was a painless condition after 1 to 3 dressings, clear weekly improvement, which the patients themselves pointed out, and complete healing was reached in 2 to 27 weeks, not forgetting the previous long evolution of up to 240 weeks without evidence of improvement. As conclusions, Cronocol® implant significantly improved the quality of life of patients with venous ulcers, contributed to cicatrisation of those resistant to other treatments, and in fact decreased expenses in health care with this pathology. Keywords: Leg ulcer, venous ulcer, chronic venous insufficiency, Cronocol®, collagen, gentamicin, metalloproteinases |
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Treatment of Venous Ulcers with Cronocol® implants – analysis of 10 casesTratamento de Úlceras Venosas com implantes de Cronocol® – análise de 10 casosChronic venous insufficiency (CVI) of lower limbs is a health problem with a clear negative social impact in Portugal and worldwide. Venous ulcer is a major reason for work absenteeism. Its physiopathology is not well known, has a natural history of healing and recurrence, and a difficult healing process that is time and money consuming for health care facilities. The goal was to clinically 10 pa- tients with chronic venous ulcer, painful on the inclusion date and resistant to other treatments, without other associated pathologies, treated with Cronocol® implants. Three parameters were evaluated: pain, treatment continuity, cicatrisation. As outpatients, they had the implants applied on a weekly basis, dry gauze applied over them and elastic bandage of the leg. Data of the evolution with other treatments before Cronocol®, always including elastic compression, were used as control group. In the first ten patients (aged from 57 to 82) there was a painless condition after 1 to 3 dressings, clear weekly improvement, which the patients themselves pointed out, and complete healing was reached in 2 to 27 weeks, not forgetting the previous long evolution of up to 240 weeks without evidence of improvement. As conclusions, Cronocol® implant significantly improved the quality of life of patients with venous ulcers, contributed to cicatrisation of those resistant to other treatments, and in fact decreased expenses in health care with this pathology. Keywords: Leg ulcer, venous ulcer, chronic venous insufficiency, Cronocol®, collagen, gentamicin, metalloproteinases A insuficiência venosa crónica (IVC) dos membros inferiores é um problema de saúde com impacto negativo manifesto nas sociedades portuguesa e mundial, sendo a úlcera varicosa uma importante razão de ausência ao trabalho. A sua fisiopatologia não está totalmente esclarecida, o seu curso habitual é de cura alternando com recidiva, com uma dificuldade na cicatrização que prolonga e encarece o recurso aos cuidados de saúde. O objectivo foi avaliar clinicamente doentes com úlcera venosa crónica dolorosa à data da inclusão, sem patologias associadas e resistente a outros tratamentos, tratados com implantes de Cronocol® (colagénio com sulfato de gentamicina). Foram considerados três parâmetros: dor, adesão ao tratamento, cicatrização. O implante foi aplicado semanalmente em regime de consulta externa, posteriormente coberto com compressas, e por fim ligadura elástica na perna. Os dados da evolução com outros tratamentos antes do Cronocol®, dos quais sempre fez parte a contenção elástica, foram usados como grupo controlo. O resultado nos primeiros dez doentes (idades entre os 57 e aos 82 anos) foi o estado assintomático ao fim de 1 a 3 pensos, a evidente evolução favorável semanal (sendo os próprios doentes a referir tal aspecto), e a cicatrização completa ao fim de 2 a 27 semanas (não esquecendo a evolu- ção arrastada prévia até 240 semanas sem melhoria).Concluindo, o implante de Cronocol® melhorou substancialmente a qualidade de vida destes doentes com úlcera venosa, conseguindo-se com ele a cicatrização de úlceras venosas resistentes a outros tratamentos, além de uma redução dos custos de saúde com esta patologia. Palavras-Chave: Úlcera de perna, úlcera varicosa, insuficiência venosa crónica, Cronocol®, colagénio, gentamicina, metaloproteinases Sociedade Portuguesa de Cirurgia2012-06-29info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://revista.spcir.com/index.php/spcir/article/view/42Revista Portuguesa de Cirurgia; No 21 (2012): Junho 2012 - II Série; 13-20Revista Portuguesa de Cirurgia; No 21 (2012): Junho 2012 - II Série; 13-202183-11651646-6918reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spcir.com/index.php/spcir/article/view/42https://revista.spcir.com/index.php/spcir/article/view/42/39Copyright (c) 2016 Revista Portuguesa de Cirurgiainfo:eu-repo/semantics/openAccessCosta de Almeida, Carlos E.Reis, Luis S.Carvalho, Luis F.Costa de Almeida, Carlos M.2024-03-14T22:05:33Zoai:revista.spcir.com:article/42Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T04:00:55.352247Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Treatment of Venous Ulcers with Cronocol® implants – analysis of 10 cases Tratamento de Úlceras Venosas com implantes de Cronocol® – análise de 10 casos |
title |
Treatment of Venous Ulcers with Cronocol® implants – analysis of 10 cases |
spellingShingle |
Treatment of Venous Ulcers with Cronocol® implants – analysis of 10 cases Costa de Almeida, Carlos E. |
title_short |
Treatment of Venous Ulcers with Cronocol® implants – analysis of 10 cases |
title_full |
Treatment of Venous Ulcers with Cronocol® implants – analysis of 10 cases |
title_fullStr |
Treatment of Venous Ulcers with Cronocol® implants – analysis of 10 cases |
title_full_unstemmed |
Treatment of Venous Ulcers with Cronocol® implants – analysis of 10 cases |
title_sort |
Treatment of Venous Ulcers with Cronocol® implants – analysis of 10 cases |
author |
Costa de Almeida, Carlos E. |
author_facet |
Costa de Almeida, Carlos E. Reis, Luis S. Carvalho, Luis F. Costa de Almeida, Carlos M. |
author_role |
author |
author2 |
Reis, Luis S. Carvalho, Luis F. Costa de Almeida, Carlos M. |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Costa de Almeida, Carlos E. Reis, Luis S. Carvalho, Luis F. Costa de Almeida, Carlos M. |
description |
Chronic venous insufficiency (CVI) of lower limbs is a health problem with a clear negative social impact in Portugal and worldwide. Venous ulcer is a major reason for work absenteeism. Its physiopathology is not well known, has a natural history of healing and recurrence, and a difficult healing process that is time and money consuming for health care facilities. The goal was to clinically 10 pa- tients with chronic venous ulcer, painful on the inclusion date and resistant to other treatments, without other associated pathologies, treated with Cronocol® implants. Three parameters were evaluated: pain, treatment continuity, cicatrisation. As outpatients, they had the implants applied on a weekly basis, dry gauze applied over them and elastic bandage of the leg. Data of the evolution with other treatments before Cronocol®, always including elastic compression, were used as control group. In the first ten patients (aged from 57 to 82) there was a painless condition after 1 to 3 dressings, clear weekly improvement, which the patients themselves pointed out, and complete healing was reached in 2 to 27 weeks, not forgetting the previous long evolution of up to 240 weeks without evidence of improvement. As conclusions, Cronocol® implant significantly improved the quality of life of patients with venous ulcers, contributed to cicatrisation of those resistant to other treatments, and in fact decreased expenses in health care with this pathology. Keywords: Leg ulcer, venous ulcer, chronic venous insufficiency, Cronocol®, collagen, gentamicin, metalloproteinases |
publishDate |
2012 |
dc.date.none.fl_str_mv |
2012-06-29 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://revista.spcir.com/index.php/spcir/article/view/42 |
url |
https://revista.spcir.com/index.php/spcir/article/view/42 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://revista.spcir.com/index.php/spcir/article/view/42 https://revista.spcir.com/index.php/spcir/article/view/42/39 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2016 Revista Portuguesa de Cirurgia info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2016 Revista Portuguesa de Cirurgia |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Cirurgia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Cirurgia |
dc.source.none.fl_str_mv |
Revista Portuguesa de Cirurgia; No 21 (2012): Junho 2012 - II Série; 13-20 Revista Portuguesa de Cirurgia; No 21 (2012): Junho 2012 - II Série; 13-20 2183-1165 1646-6918 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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