Angiosarcoma of the lower limb misdiagnosed as deep thrombophlebitis – a review

• Autor(a) principal: Murinello, António
• Data de Publicação: 2007
• Outros Autores: Fernandes, Cândida, Neta, Jorge, Árias, Jesus, Afonso, Ana, Cabral, Vitória, Germano, Nuno, Mendonça, Paula, Ribeiro, Analisa, Lázaro, António, P. Pereira, Sílvia
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: https://revista.spmi.pt/index.php/rpmi/article/view/1577
• topic: Angiossarcoma do membro inferior; Linfedema; tromboflebite profunda; Angiosarcoma of the lower limb; Deep Thrombophlebitis; Lymphoedema

Angiosarcomas are very rare sarcomas with vascular differentiation, high-grade malignant behaviour, early metastasis and generally bad prognosis. Early diagnosis is very important for adequate radical ablative surgery in order to obtain a better prognosis. The authors present a case of very aggressive angiosarcoma of the leg, admitted in a very advanced stage with extensive metastases, due to an initial misdiagnosis of deep venous thrombosis. The patient died early during the period of evaluation. A review of superficial types of angiosarcomas is presented, including the clinico-pathological classification, characterizing its multifocal aspects, frequent extensive metastases, diagnostic studies for defining vascular tumours, early local recurrences after apparent radical ablative surgery, and therapeutic modalities.