Chemical study and biological activity evaluation of two Azorean Macroalgae: Ulva rigida and Gelidium microdon

Detalhes bibliográficos
Autor(a) principal: Silva, Madalena
Data de Publicação: 2013
Outros Autores: Vieira, Luís M., Almeida, Ana Paula, Silva, Artur M. S., Seca, Ana M. L., Barreto, Maria do Carmo, Neto, Ana I., Pedro, Madalena, Pinto, Eugénia, Kijjoa, Anake
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.3/2163
Resumo: Copyright: © 2013 Silva M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credite.
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spelling Chemical study and biological activity evaluation of two Azorean Macroalgae: Ulva rigida and Gelidium microdonAzoresMacroalgaeLumichromeAntitumorAntimicrobialUlva rigidaGelidium microdonIsofucosterol7(E)-3β-hydroxy-5α,6α-epoxymegastigmane(+)-dehydrovomifoliolCopyright: © 2013 Silva M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credite.The green macroalga Ulva rigida C. Agardh (Chlorophyta) and the red macroalga Gelidium microdon Kützing (Rhodophyta), collected from the Azorean archipelago, were investigated for their secondary metabolites and their in vitro growth inhibitory effect on three human tumor cell lines: MCF-7 (breast adenocarcinoma), NCI-H460 (non-small cell lung cancer) and A375-C5 (melanoma), as well as for their antifungal and antibacterial activities. The methanol extract of U. rigida furnished isofucosterol (1), 7(E)-3β-hydroxy-5α,6α-epoxymegastigmane (2) and (+)-dehydrovomifoliol (3) while the methanol extract of G. microdon yielded cholesterol (4) and lumichrome (5). The crude extracts of both macroalgae were found to be moderately active against the three cell lines whereas compound 1 showed a weak effect and compound 2 was inactive. The crude extracts of the two macroalgae were found to be moderately active against some fungi and bacteria while compounds 1 and 2 were inactive against all microorganisms tested.OMICS Publishing GroupRepositório da Universidade dos AçoresSilva, MadalenaVieira, Luís M.Almeida, Ana PaulaSilva, Artur M. S.Seca, Ana M. L.Barreto, Maria do CarmoNeto, Ana I.Pedro, MadalenaPinto, EugéniaKijjoa, Anake2013-07-26T09:42:46Z2013-042013-04-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.3/2163engSilva M, Vieira L, Almeida AP, Silva A, Seca A, Barreto MC, Neto AI, Pedro M, Pinto E & Kijjoa A (2013) (published online). "Chemical Study and Biological Activity Evaluation of Two Azorean Macroalgae: Ulva rigida and Gelidium microdon". «Oceanography», 1(1): 102.2332-2632info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-12-20T14:29:55Zoai:repositorio.uac.pt:10400.3/2163Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:24:52.701435Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Chemical study and biological activity evaluation of two Azorean Macroalgae: Ulva rigida and Gelidium microdon
title Chemical study and biological activity evaluation of two Azorean Macroalgae: Ulva rigida and Gelidium microdon
spellingShingle Chemical study and biological activity evaluation of two Azorean Macroalgae: Ulva rigida and Gelidium microdon
Silva, Madalena
Azores
Macroalgae
Lumichrome
Antitumor
Antimicrobial
Ulva rigida
Gelidium microdon
Isofucosterol
7(E)-3β-hydroxy-5α,6α-epoxymegastigmane
(+)-dehydrovomifoliol
title_short Chemical study and biological activity evaluation of two Azorean Macroalgae: Ulva rigida and Gelidium microdon
title_full Chemical study and biological activity evaluation of two Azorean Macroalgae: Ulva rigida and Gelidium microdon
title_fullStr Chemical study and biological activity evaluation of two Azorean Macroalgae: Ulva rigida and Gelidium microdon
title_full_unstemmed Chemical study and biological activity evaluation of two Azorean Macroalgae: Ulva rigida and Gelidium microdon
title_sort Chemical study and biological activity evaluation of two Azorean Macroalgae: Ulva rigida and Gelidium microdon
author Silva, Madalena
author_facet Silva, Madalena
Vieira, Luís M.
Almeida, Ana Paula
Silva, Artur M. S.
Seca, Ana M. L.
Barreto, Maria do Carmo
Neto, Ana I.
Pedro, Madalena
Pinto, Eugénia
Kijjoa, Anake
author_role author
author2 Vieira, Luís M.
Almeida, Ana Paula
Silva, Artur M. S.
Seca, Ana M. L.
Barreto, Maria do Carmo
Neto, Ana I.
Pedro, Madalena
Pinto, Eugénia
Kijjoa, Anake
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório da Universidade dos Açores
dc.contributor.author.fl_str_mv Silva, Madalena
Vieira, Luís M.
Almeida, Ana Paula
Silva, Artur M. S.
Seca, Ana M. L.
Barreto, Maria do Carmo
Neto, Ana I.
Pedro, Madalena
Pinto, Eugénia
Kijjoa, Anake
dc.subject.por.fl_str_mv Azores
Macroalgae
Lumichrome
Antitumor
Antimicrobial
Ulva rigida
Gelidium microdon
Isofucosterol
7(E)-3β-hydroxy-5α,6α-epoxymegastigmane
(+)-dehydrovomifoliol
topic Azores
Macroalgae
Lumichrome
Antitumor
Antimicrobial
Ulva rigida
Gelidium microdon
Isofucosterol
7(E)-3β-hydroxy-5α,6α-epoxymegastigmane
(+)-dehydrovomifoliol
description Copyright: © 2013 Silva M, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credite.
publishDate 2013
dc.date.none.fl_str_mv 2013-07-26T09:42:46Z
2013-04
2013-04-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.3/2163
url http://hdl.handle.net/10400.3/2163
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Silva M, Vieira L, Almeida AP, Silva A, Seca A, Barreto MC, Neto AI, Pedro M, Pinto E & Kijjoa A (2013) (published online). "Chemical Study and Biological Activity Evaluation of Two Azorean Macroalgae: Ulva rigida and Gelidium microdon". «Oceanography», 1(1): 102.
2332-2632
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv OMICS Publishing Group
publisher.none.fl_str_mv OMICS Publishing Group
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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