Exacerbation of Recalcitrant Cutaneous Sarcoidosis with Adalimumab - a Paradoxical Effect? A Case Report
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2013 |
| Outros Autores: | , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10400.17/1804 |
Resumo: | The paradoxical adverse effects of tumor necrosis factor-alpha (TNF-alpha) antagonists have been described frequently as a result of the widespread use of these drugs. Among the TNF-alpha blocking agents, few reports exist relating the use of adalimumab in cutaneous sarcoidosis, although all of them show good results. More recently, sarcoidosis onsets have been reported with various TNF-alpha inhibitors. The current case is, to our knowledge, the first to describe the exacerbation of cutaneous lesions of sarcoidosis treated with adalimumab. |
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Exacerbation of Recalcitrant Cutaneous Sarcoidosis with Adalimumab - a Paradoxical Effect? A Case ReportAgravamento de Lesões Refratárias de Sarcoidose Cutânea com Adalimumab - um Efeito Paradoxal? Relato de um CasoHSAC DERAnti-InflamatóriosEfeitos AdversosAnticorpos Monoclonais HumanizadosBiópsiaEvolução da DoençaSarcoidoseDoenças da PeleResultado de TratamentoFactor de Necrose Tumoral AlfaThe paradoxical adverse effects of tumor necrosis factor-alpha (TNF-alpha) antagonists have been described frequently as a result of the widespread use of these drugs. Among the TNF-alpha blocking agents, few reports exist relating the use of adalimumab in cutaneous sarcoidosis, although all of them show good results. More recently, sarcoidosis onsets have been reported with various TNF-alpha inhibitors. The current case is, to our knowledge, the first to describe the exacerbation of cutaneous lesions of sarcoidosis treated with adalimumab.ScieloRepositório do Centro Hospitalar Universitário de Lisboa Central, EPESantos, GSousa, LJoão, A2014-05-23T16:05:29Z20132013-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.17/1804engAn Bras Dermatol. 2013 Nov-Dec;88(6 Suppl 1):26-8info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T09:33:25Zoai:repositorio.chlc.min-saude.pt:10400.17/1804Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:19:13.464465Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Exacerbation of Recalcitrant Cutaneous Sarcoidosis with Adalimumab - a Paradoxical Effect? A Case Report Agravamento de Lesões Refratárias de Sarcoidose Cutânea com Adalimumab - um Efeito Paradoxal? Relato de um Caso |
| title |
Exacerbation of Recalcitrant Cutaneous Sarcoidosis with Adalimumab - a Paradoxical Effect? A Case Report |
| spellingShingle |
Exacerbation of Recalcitrant Cutaneous Sarcoidosis with Adalimumab - a Paradoxical Effect? A Case Report Santos, G HSAC DER Anti-Inflamatórios Efeitos Adversos Anticorpos Monoclonais Humanizados Biópsia Evolução da Doença Sarcoidose Doenças da Pele Resultado de Tratamento Factor de Necrose Tumoral Alfa |
| title_short |
Exacerbation of Recalcitrant Cutaneous Sarcoidosis with Adalimumab - a Paradoxical Effect? A Case Report |
| title_full |
Exacerbation of Recalcitrant Cutaneous Sarcoidosis with Adalimumab - a Paradoxical Effect? A Case Report |
| title_fullStr |
Exacerbation of Recalcitrant Cutaneous Sarcoidosis with Adalimumab - a Paradoxical Effect? A Case Report |
| title_full_unstemmed |
Exacerbation of Recalcitrant Cutaneous Sarcoidosis with Adalimumab - a Paradoxical Effect? A Case Report |
| title_sort |
Exacerbation of Recalcitrant Cutaneous Sarcoidosis with Adalimumab - a Paradoxical Effect? A Case Report |
| author |
Santos, G |
| author_facet |
Santos, G Sousa, L João, A |
| author_role |
author |
| author2 |
Sousa, L João, A |
| author2_role |
author author |
| dc.contributor.none.fl_str_mv |
Repositório do Centro Hospitalar Universitário de Lisboa Central, EPE |
| dc.contributor.author.fl_str_mv |
Santos, G Sousa, L João, A |
| dc.subject.por.fl_str_mv |
HSAC DER Anti-Inflamatórios Efeitos Adversos Anticorpos Monoclonais Humanizados Biópsia Evolução da Doença Sarcoidose Doenças da Pele Resultado de Tratamento Factor de Necrose Tumoral Alfa |
| topic |
HSAC DER Anti-Inflamatórios Efeitos Adversos Anticorpos Monoclonais Humanizados Biópsia Evolução da Doença Sarcoidose Doenças da Pele Resultado de Tratamento Factor de Necrose Tumoral Alfa |
| description |
The paradoxical adverse effects of tumor necrosis factor-alpha (TNF-alpha) antagonists have been described frequently as a result of the widespread use of these drugs. Among the TNF-alpha blocking agents, few reports exist relating the use of adalimumab in cutaneous sarcoidosis, although all of them show good results. More recently, sarcoidosis onsets have been reported with various TNF-alpha inhibitors. The current case is, to our knowledge, the first to describe the exacerbation of cutaneous lesions of sarcoidosis treated with adalimumab. |
| publishDate |
2013 |
| dc.date.none.fl_str_mv |
2013 2013-01-01T00:00:00Z 2014-05-23T16:05:29Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.17/1804 |
| url |
http://hdl.handle.net/10400.17/1804 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
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An Bras Dermatol. 2013 Nov-Dec;88(6 Suppl 1):26-8 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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Scielo |
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Scielo |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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