PRIMARY CUTANEOUS FOLLICLE CENTER LYMPHOMA – A DIAGNOSIS TO CONSIDER

Detalhes bibliográficos
Autor(a) principal: Resende, Cristina
Data de Publicação: 2015
Outros Autores: Araújo, Catarina, Santos, R., Brito, Celeste
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.29021/spdv.72.4.334
Resumo: Introduction: Follicular lymphoma is the most common B-cell lymphoma to occur as a primary tumor of skin.Case report: The case of a 69-year-old caucasian female patient, with a 1 year history of a painless nodule, localized in the frontal region, which had been observed several times on urgency room. On examination, we observed a nontender nodule, 3x2 cm, localized in the frontal region with small papules at the periphery. Histopathologic examination of a biopsy from the nodule was suggestive of follicular lymphoma.Immunophenotyping: CD20+, CD3-, CD5-, CD10+, Bcl2+ in rare cells. The patient was observed by Hematology/ Oncology and the staging was negative and a course of palliative chemotherapy with R-CHOP, followed by radiotherapy was given. During a follow-up of 6 months there wasn´t any evidence of recurrences.Conclusion: This case report intends emphasize the relevance of educate the doctors for the diagnosis of this disease.
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spelling PRIMARY CUTANEOUS FOLLICLE CENTER LYMPHOMA – A DIAGNOSIS TO CONSIDERLINFOMA DE CENTRO FOLICULAR CUTÂNEO PRIMÁRIO – UMA ENTIDADE A CONSIDERARLymphomafollicularSkin neoplasmsLinfoma folicularNeoplasias da peleIntroduction: Follicular lymphoma is the most common B-cell lymphoma to occur as a primary tumor of skin.Case report: The case of a 69-year-old caucasian female patient, with a 1 year history of a painless nodule, localized in the frontal region, which had been observed several times on urgency room. On examination, we observed a nontender nodule, 3x2 cm, localized in the frontal region with small papules at the periphery. Histopathologic examination of a biopsy from the nodule was suggestive of follicular lymphoma.Immunophenotyping: CD20+, CD3-, CD5-, CD10+, Bcl2+ in rare cells. The patient was observed by Hematology/ Oncology and the staging was negative and a course of palliative chemotherapy with R-CHOP, followed by radiotherapy was given. During a follow-up of 6 months there wasn´t any evidence of recurrences.Conclusion: This case report intends emphasize the relevance of educate the doctors for the diagnosis of this disease.Introdução: O linfoma de centro folicular cutâneo primário (LCFCP) é o subtipo mais comum de linfoma de células B primário.Caso clínico: Doente do sexo feminino, 69 anos, assintomática até há 1 ano, altura em que refere o aparecimento de um nódulo, indolor, na região frontal, tendo sido observada várias vezes no Serviço de Urgência. Ao exame objetivo, observava-se um nódulo, de coloração rosada, localizado na região frontal direita, com 3x2 cm, circundado por pequenas pápulas. Efetuou-se biópsia do nódulo e a histologia foi sugestiva de linfoma folicular.Imunofenotipagem: CD20+, CD3-, CD5-, CD10+, Bcl2+ em raras células. A doente foi enviada para a consulta de Hemato-Oncologia, tendo realizado estadiamento, que foi negativo e tratamento com R-CHOP, seguido de radioterapia. No follow-up de 6 meses não se diagnosticaram recidivas.Conclusão: Apresenta-se este caso para enfatizar a importância de alertar as outras especialidades para esta entidade, para a diagnosticar atempadamente.Sociedade Portuguesa de Dermatologia e Venereologia2015-04-13T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.72.4.334oai:ojs.revista.spdv.com.pt:article/334Journal of the Portuguese Society of Dermatology and Venereology; Vol 72 No 4 (2014): Outubro - Dezembro; 587-591Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 72 n. 4 (2014): Outubro - Dezembro; 587-5912182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spdv.com.pt/index.php/spdv/article/view/334https://doi.org/10.29021/spdv.72.4.334https://revista.spdv.com.pt/index.php/spdv/article/view/334/307Resende, CristinaAraújo, CatarinaSantos, R.Brito, Celesteinfo:eu-repo/semantics/openAccess2022-10-06T12:34:51Zoai:ojs.revista.spdv.com.pt:article/334Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:10:51.003331Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv PRIMARY CUTANEOUS FOLLICLE CENTER LYMPHOMA – A DIAGNOSIS TO CONSIDER
LINFOMA DE CENTRO FOLICULAR CUTÂNEO PRIMÁRIO – UMA ENTIDADE A CONSIDERAR
title PRIMARY CUTANEOUS FOLLICLE CENTER LYMPHOMA – A DIAGNOSIS TO CONSIDER
spellingShingle PRIMARY CUTANEOUS FOLLICLE CENTER LYMPHOMA – A DIAGNOSIS TO CONSIDER
Resende, Cristina
Lymphoma
follicular
Skin neoplasms
Linfoma folicular
Neoplasias da pele
title_short PRIMARY CUTANEOUS FOLLICLE CENTER LYMPHOMA – A DIAGNOSIS TO CONSIDER
title_full PRIMARY CUTANEOUS FOLLICLE CENTER LYMPHOMA – A DIAGNOSIS TO CONSIDER
title_fullStr PRIMARY CUTANEOUS FOLLICLE CENTER LYMPHOMA – A DIAGNOSIS TO CONSIDER
title_full_unstemmed PRIMARY CUTANEOUS FOLLICLE CENTER LYMPHOMA – A DIAGNOSIS TO CONSIDER
title_sort PRIMARY CUTANEOUS FOLLICLE CENTER LYMPHOMA – A DIAGNOSIS TO CONSIDER
author Resende, Cristina
author_facet Resende, Cristina
Araújo, Catarina
Santos, R.
Brito, Celeste
author_role author
author2 Araújo, Catarina
Santos, R.
Brito, Celeste
author2_role author
author
author
dc.contributor.author.fl_str_mv Resende, Cristina
Araújo, Catarina
Santos, R.
Brito, Celeste
dc.subject.por.fl_str_mv Lymphoma
follicular
Skin neoplasms
Linfoma folicular
Neoplasias da pele
topic Lymphoma
follicular
Skin neoplasms
Linfoma folicular
Neoplasias da pele
description Introduction: Follicular lymphoma is the most common B-cell lymphoma to occur as a primary tumor of skin.Case report: The case of a 69-year-old caucasian female patient, with a 1 year history of a painless nodule, localized in the frontal region, which had been observed several times on urgency room. On examination, we observed a nontender nodule, 3x2 cm, localized in the frontal region with small papules at the periphery. Histopathologic examination of a biopsy from the nodule was suggestive of follicular lymphoma.Immunophenotyping: CD20+, CD3-, CD5-, CD10+, Bcl2+ in rare cells. The patient was observed by Hematology/ Oncology and the staging was negative and a course of palliative chemotherapy with R-CHOP, followed by radiotherapy was given. During a follow-up of 6 months there wasn´t any evidence of recurrences.Conclusion: This case report intends emphasize the relevance of educate the doctors for the diagnosis of this disease.
publishDate 2015
dc.date.none.fl_str_mv 2015-04-13T00:00:00Z
dc.type.driver.fl_str_mv journal article
info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.29021/spdv.72.4.334
oai:ojs.revista.spdv.com.pt:article/334
url https://doi.org/10.29021/spdv.72.4.334
identifier_str_mv oai:ojs.revista.spdv.com.pt:article/334
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://revista.spdv.com.pt/index.php/spdv/article/view/334
https://doi.org/10.29021/spdv.72.4.334
https://revista.spdv.com.pt/index.php/spdv/article/view/334/307
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
dc.source.none.fl_str_mv Journal of the Portuguese Society of Dermatology and Venereology; Vol 72 No 4 (2014): Outubro - Dezembro; 587-591
Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 72 n. 4 (2014): Outubro - Dezembro; 587-591
2182-2409
2182-2395
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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