Hierridin B Isolated from a Marine Cyanobacterium Alters VDAC1, Mitochondrial Activity, and Cell Cycle Genes on HT-29 Colon Adenocarcinoma Cells

Detalhes bibliográficos
Autor(a) principal: Freitas, Sara
Data de Publicação: 2016
Outros Autores: Martins, Rosario, Costa, Margarida, Leão, Pedro, Vitorino, Rui, Vasconcelos, Vitor, Urbatzka, Ralph
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.22/9269
Resumo: Hierridin B was isolated from a marine cyanobacterium Cyanobium sp. strain and induced cytotoxicity selectively in HT-29 adenocarcinoma cells. The underlying molecular mechanism was not yet elucidated.
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spelling Hierridin B Isolated from a Marine Cyanobacterium Alters VDAC1, Mitochondrial Activity, and Cell Cycle Genes on HT-29 Colon Adenocarcinoma CellsNatural productsBioactive compoundsAnticancer drugsColon cancer cellsMarine cyanobacteriaMitochondriaVdac1Cell cycleProteomicsHigh content analysisHierridin B was isolated from a marine cyanobacterium Cyanobium sp. strain and induced cytotoxicity selectively in HT-29 adenocarcinoma cells. The underlying molecular mechanism was not yet elucidated.MDPI Open Access JournalsRepositório Científico do Instituto Politécnico do PortoFreitas, SaraMartins, RosarioCosta, MargaridaLeão, PedroVitorino, RuiVasconcelos, VitorUrbatzka, Ralph2017-01-16T10:51:31Z20162016-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.22/9269eng10.3390/md14090158info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-13T12:50:01Zoai:recipp.ipp.pt:10400.22/9269Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T17:29:34.414420Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Hierridin B Isolated from a Marine Cyanobacterium Alters VDAC1, Mitochondrial Activity, and Cell Cycle Genes on HT-29 Colon Adenocarcinoma Cells
title Hierridin B Isolated from a Marine Cyanobacterium Alters VDAC1, Mitochondrial Activity, and Cell Cycle Genes on HT-29 Colon Adenocarcinoma Cells
spellingShingle Hierridin B Isolated from a Marine Cyanobacterium Alters VDAC1, Mitochondrial Activity, and Cell Cycle Genes on HT-29 Colon Adenocarcinoma Cells
Freitas, Sara
Natural products
Bioactive compounds
Anticancer drugs
Colon cancer cells
Marine cyanobacteria
Mitochondria
Vdac1
Cell cycle
Proteomics
High content analysis
title_short Hierridin B Isolated from a Marine Cyanobacterium Alters VDAC1, Mitochondrial Activity, and Cell Cycle Genes on HT-29 Colon Adenocarcinoma Cells
title_full Hierridin B Isolated from a Marine Cyanobacterium Alters VDAC1, Mitochondrial Activity, and Cell Cycle Genes on HT-29 Colon Adenocarcinoma Cells
title_fullStr Hierridin B Isolated from a Marine Cyanobacterium Alters VDAC1, Mitochondrial Activity, and Cell Cycle Genes on HT-29 Colon Adenocarcinoma Cells
title_full_unstemmed Hierridin B Isolated from a Marine Cyanobacterium Alters VDAC1, Mitochondrial Activity, and Cell Cycle Genes on HT-29 Colon Adenocarcinoma Cells
title_sort Hierridin B Isolated from a Marine Cyanobacterium Alters VDAC1, Mitochondrial Activity, and Cell Cycle Genes on HT-29 Colon Adenocarcinoma Cells
author Freitas, Sara
author_facet Freitas, Sara
Martins, Rosario
Costa, Margarida
Leão, Pedro
Vitorino, Rui
Vasconcelos, Vitor
Urbatzka, Ralph
author_role author
author2 Martins, Rosario
Costa, Margarida
Leão, Pedro
Vitorino, Rui
Vasconcelos, Vitor
Urbatzka, Ralph
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Repositório Científico do Instituto Politécnico do Porto
dc.contributor.author.fl_str_mv Freitas, Sara
Martins, Rosario
Costa, Margarida
Leão, Pedro
Vitorino, Rui
Vasconcelos, Vitor
Urbatzka, Ralph
dc.subject.por.fl_str_mv Natural products
Bioactive compounds
Anticancer drugs
Colon cancer cells
Marine cyanobacteria
Mitochondria
Vdac1
Cell cycle
Proteomics
High content analysis
topic Natural products
Bioactive compounds
Anticancer drugs
Colon cancer cells
Marine cyanobacteria
Mitochondria
Vdac1
Cell cycle
Proteomics
High content analysis
description Hierridin B was isolated from a marine cyanobacterium Cyanobium sp. strain and induced cytotoxicity selectively in HT-29 adenocarcinoma cells. The underlying molecular mechanism was not yet elucidated.
publishDate 2016
dc.date.none.fl_str_mv 2016
2016-01-01T00:00:00Z
2017-01-16T10:51:31Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.22/9269
url http://hdl.handle.net/10400.22/9269
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.3390/md14090158
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI Open Access Journals
publisher.none.fl_str_mv MDPI Open Access Journals
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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