Food processing and cancer risk in Europe
| Autor(a) principal: | |
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| Data de Publicação: | 2023 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10362/153984 |
Resumo: | Funding Information: This work was supported by Cancer Research UK (C33493/A29678), World Cancer Research Fund International (IIG_FULL_2020_033), and the Institut National du Cancer (INCa number 2021–138). The coordination of EPIC is financially supported by the IARC and the Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, which has additional infrastructure support provided by the UK National Institute for Health and Care Research Imperial Biomedical Research Centre. The national cohorts are supported by the Danish Cancer Society (Denmark); Ligue Contre le Cancer, Institut Gustave Roussy, Mutuelle Générale de l'Education Nationale, Institut National de la Santé et de la Recherche Médicale (INSERM; France); German Cancer Aid, German Cancer Research Center (DKFZ), German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Federal Ministry of Education and Research (BMBF; Germany); Associazione Italiana per la Ricerca sul Cancro-AIRC–Italy, Compagnia di SanPaolo and National Research Council (Italy); Dutch Ministry of Public Health, Welfare and Sports (VWS), Netherlands Cancer Registry (NKR), LK Research Funds, Dutch Prevention Funds, Dutch ZON (Zorg Onderzoek Nederland), World Cancer Research Fund, Statistics Netherlands (Netherlands); Health Research Fund (FIS)—Instituto de Salud Carlos III (ISCIII), Regional Governments of Andalucía, Asturias, Basque Country, Murcia and Navarra, and the Catalan Institute of Oncology (ICO; Spain); Swedish Cancer Society, Swedish Research Council and County Councils of Skåne and Västerbotten (Sweden); and Cancer Research UK (14136 to EPIC–Norfolk; C8221/A29017 to EPIC–Oxford) and Medical Research Council (1000143 to EPIC–Norfolk; MR/M012190/1 to EPIC–Oxford; UK). Where authors are identified as personnel of the International Agency for Research on Cancer or WHO, they are responsible for the views expressed in this Article and they do not necessarily represent the decisions, policy, or views of the International Agency for Research on Cancer or WHO. Publisher Copyright: © 2023 World Health Organization UPDATE NOTICE Correction to Lancet Planet Health 2023; 7: e219–32. The Lancet Planetary Health. 2023;7(5):e357. Scopus ID: 85158098931 |
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Food processing and cancer risk in Europeresults from the prospective EPIC cohort studyMedicine (miscellaneous)Health(social science)Health PolicyPublic Health, Environmental and Occupational HealthSDG 3 - Good Health and Well-beingFunding Information: This work was supported by Cancer Research UK (C33493/A29678), World Cancer Research Fund International (IIG_FULL_2020_033), and the Institut National du Cancer (INCa number 2021–138). The coordination of EPIC is financially supported by the IARC and the Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, which has additional infrastructure support provided by the UK National Institute for Health and Care Research Imperial Biomedical Research Centre. The national cohorts are supported by the Danish Cancer Society (Denmark); Ligue Contre le Cancer, Institut Gustave Roussy, Mutuelle Générale de l'Education Nationale, Institut National de la Santé et de la Recherche Médicale (INSERM; France); German Cancer Aid, German Cancer Research Center (DKFZ), German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Federal Ministry of Education and Research (BMBF; Germany); Associazione Italiana per la Ricerca sul Cancro-AIRC–Italy, Compagnia di SanPaolo and National Research Council (Italy); Dutch Ministry of Public Health, Welfare and Sports (VWS), Netherlands Cancer Registry (NKR), LK Research Funds, Dutch Prevention Funds, Dutch ZON (Zorg Onderzoek Nederland), World Cancer Research Fund, Statistics Netherlands (Netherlands); Health Research Fund (FIS)—Instituto de Salud Carlos III (ISCIII), Regional Governments of Andalucía, Asturias, Basque Country, Murcia and Navarra, and the Catalan Institute of Oncology (ICO; Spain); Swedish Cancer Society, Swedish Research Council and County Councils of Skåne and Västerbotten (Sweden); and Cancer Research UK (14136 to EPIC–Norfolk; C8221/A29017 to EPIC–Oxford) and Medical Research Council (1000143 to EPIC–Norfolk; MR/M012190/1 to EPIC–Oxford; UK). Where authors are identified as personnel of the International Agency for Research on Cancer or WHO, they are responsible for the views expressed in this Article and they do not necessarily represent the decisions, policy, or views of the International Agency for Research on Cancer or WHO. Publisher Copyright: © 2023 World Health Organization UPDATE NOTICE Correction to Lancet Planet Health 2023; 7: e219–32. The Lancet Planetary Health. 2023;7(5):e357. Scopus ID: 85158098931Background: Food processing has been hypothesised to play a role in cancer development; however, data from large-scale epidemiological studies are scarce. This study investigated the association between dietary intake according to amount of food processing and risk of cancer at 25 anatomical sites using data from the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Methods: This study used data from the prospective EPIC cohort study, which recruited participants between March 18, 1991, and July 2, 2001, from 23 centres in ten European countries. Participant eligibility within each cohort was based on geographical or administrative boundaries. Participants were excluded if they had a cancer diagnosis before recruitment, had missing information for the NOVA food processing classification, or were within the top and bottom 1% for ratio of energy intake to energy requirement. Validated dietary questionnaires were used to obtain information on food and drink consumption. Participants with cancer were identified using cancer registries or during follow-up from a combination of sources, including cancer and pathology centres, health insurance records, and active follow-up of participants. We performed a substitution analysis to assess the effect of replacing 10% of processed foods and ultra-processed foods with 10% of minimally processed foods on cancer risk at 25 anatomical sites using Cox proportional hazard models. Findings: 521 324 participants were recruited into EPIC, and 450 111 were included in this analysis (318 686 [70·8%] participants were female individuals and 131 425 [29·2%] were male individuals). In a multivariate model adjusted for sex, smoking, education, physical activity, height, and diabetes, a substitution of 10% of processed foods with an equal amount of minimally processed foods was associated with reduced risk of overall cancer (hazard ratio 0·96, 95% CI 0·95–0·97), head and neck cancers (0·80, 0·75–0·85), oesophageal squamous cell carcinoma (0·57, 0·51–0·64), colon cancer (0·88, 0·85–0·92), rectal cancer (0·90, 0·85–0·94), hepatocellular carcinoma (0·77, 0·68–0·87), and postmenopausal breast cancer (0·93, 0·90–0·97). The substitution of 10% of ultra-processed foods with 10% of minimally processed foods was associated with a reduced risk of head and neck cancers (0·80, 0·74–0·88), colon cancer (0·93, 0·89–0·97), and hepatocellular carcinoma (0·73, 0·62–0·86). Most of these associations remained significant when models were additionally adjusted for BMI, alcohol and dietary intake, and quality. Interpretation: This study suggests that the replacement of processed and ultra-processed foods and drinks with an equal amount of minimally processed foods might reduce the risk of various cancer types. Funding: Cancer Research UK, l'Institut National du Cancer, and World Cancer Research Fund International.Centro de Investigação em Saúde Pública (CISP/PHRC)Comprehensive Health Research Centre (CHRC) - Pólo ENSPEscola Nacional de Saúde Pública (ENSP)RUNKliemann, NathalieRauber, FernandaBertazzi Levy, RenataViallon, VivianVamos, Eszter P.Cordova, ReynaldaFreisling, HeinzCasagrande, CorinneNicolas, GenevieveAune, DagfinnTsilidis, Konstantinos K.Heath, AliciaSchulze, Matthias B.Jannasch, FranziskaSrour, BernardKaaks, RudolfRodriguez-Barranco, MiguelTagliabue, GiovannaAgudo, AntonioPanico, SalvatoreArdanaz, EvaChirlaque, María DoloresVineis, PaoloTumino, RosarioPerez-Cornago, AuroraAndersen, Julie Louise MunkTjønneland, AnneSkeie, GuriWeiderpass, ElisabeteMonteiro, Carlos AugustoGunter, Marc J.Millett, ChristopherHuybrechts, Inge2023-06-15T22:20:59Z2023-032023-03-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfhttp://hdl.handle.net/10362/153984eng2542-5196PURE: 63761444https://doi.org/10.1016/S2542-5196(23)00021-9info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:36:26Zoai:run.unl.pt:10362/153984Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:55:27.135885Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Food processing and cancer risk in Europe results from the prospective EPIC cohort study |
| title |
Food processing and cancer risk in Europe |
| spellingShingle |
Food processing and cancer risk in Europe Kliemann, Nathalie Medicine (miscellaneous) Health(social science) Health Policy Public Health, Environmental and Occupational Health SDG 3 - Good Health and Well-being |
| title_short |
Food processing and cancer risk in Europe |
| title_full |
Food processing and cancer risk in Europe |
| title_fullStr |
Food processing and cancer risk in Europe |
| title_full_unstemmed |
Food processing and cancer risk in Europe |
| title_sort |
Food processing and cancer risk in Europe |
| author |
Kliemann, Nathalie |
| author_facet |
Kliemann, Nathalie Rauber, Fernanda Bertazzi Levy, Renata Viallon, Vivian Vamos, Eszter P. Cordova, Reynalda Freisling, Heinz Casagrande, Corinne Nicolas, Genevieve Aune, Dagfinn Tsilidis, Konstantinos K. Heath, Alicia Schulze, Matthias B. Jannasch, Franziska Srour, Bernard Kaaks, Rudolf Rodriguez-Barranco, Miguel Tagliabue, Giovanna Agudo, Antonio Panico, Salvatore Ardanaz, Eva Chirlaque, María Dolores Vineis, Paolo Tumino, Rosario Perez-Cornago, Aurora Andersen, Julie Louise Munk Tjønneland, Anne Skeie, Guri Weiderpass, Elisabete Monteiro, Carlos Augusto Gunter, Marc J. Millett, Christopher Huybrechts, Inge |
| author_role |
author |
| author2 |
Rauber, Fernanda Bertazzi Levy, Renata Viallon, Vivian Vamos, Eszter P. Cordova, Reynalda Freisling, Heinz Casagrande, Corinne Nicolas, Genevieve Aune, Dagfinn Tsilidis, Konstantinos K. Heath, Alicia Schulze, Matthias B. Jannasch, Franziska Srour, Bernard Kaaks, Rudolf Rodriguez-Barranco, Miguel Tagliabue, Giovanna Agudo, Antonio Panico, Salvatore Ardanaz, Eva Chirlaque, María Dolores Vineis, Paolo Tumino, Rosario Perez-Cornago, Aurora Andersen, Julie Louise Munk Tjønneland, Anne Skeie, Guri Weiderpass, Elisabete Monteiro, Carlos Augusto Gunter, Marc J. Millett, Christopher Huybrechts, Inge |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Centro de Investigação em Saúde Pública (CISP/PHRC) Comprehensive Health Research Centre (CHRC) - Pólo ENSP Escola Nacional de Saúde Pública (ENSP) RUN |
| dc.contributor.author.fl_str_mv |
Kliemann, Nathalie Rauber, Fernanda Bertazzi Levy, Renata Viallon, Vivian Vamos, Eszter P. Cordova, Reynalda Freisling, Heinz Casagrande, Corinne Nicolas, Genevieve Aune, Dagfinn Tsilidis, Konstantinos K. Heath, Alicia Schulze, Matthias B. Jannasch, Franziska Srour, Bernard Kaaks, Rudolf Rodriguez-Barranco, Miguel Tagliabue, Giovanna Agudo, Antonio Panico, Salvatore Ardanaz, Eva Chirlaque, María Dolores Vineis, Paolo Tumino, Rosario Perez-Cornago, Aurora Andersen, Julie Louise Munk Tjønneland, Anne Skeie, Guri Weiderpass, Elisabete Monteiro, Carlos Augusto Gunter, Marc J. Millett, Christopher Huybrechts, Inge |
| dc.subject.por.fl_str_mv |
Medicine (miscellaneous) Health(social science) Health Policy Public Health, Environmental and Occupational Health SDG 3 - Good Health and Well-being |
| topic |
Medicine (miscellaneous) Health(social science) Health Policy Public Health, Environmental and Occupational Health SDG 3 - Good Health and Well-being |
| description |
Funding Information: This work was supported by Cancer Research UK (C33493/A29678), World Cancer Research Fund International (IIG_FULL_2020_033), and the Institut National du Cancer (INCa number 2021–138). The coordination of EPIC is financially supported by the IARC and the Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, which has additional infrastructure support provided by the UK National Institute for Health and Care Research Imperial Biomedical Research Centre. The national cohorts are supported by the Danish Cancer Society (Denmark); Ligue Contre le Cancer, Institut Gustave Roussy, Mutuelle Générale de l'Education Nationale, Institut National de la Santé et de la Recherche Médicale (INSERM; France); German Cancer Aid, German Cancer Research Center (DKFZ), German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), Federal Ministry of Education and Research (BMBF; Germany); Associazione Italiana per la Ricerca sul Cancro-AIRC–Italy, Compagnia di SanPaolo and National Research Council (Italy); Dutch Ministry of Public Health, Welfare and Sports (VWS), Netherlands Cancer Registry (NKR), LK Research Funds, Dutch Prevention Funds, Dutch ZON (Zorg Onderzoek Nederland), World Cancer Research Fund, Statistics Netherlands (Netherlands); Health Research Fund (FIS)—Instituto de Salud Carlos III (ISCIII), Regional Governments of Andalucía, Asturias, Basque Country, Murcia and Navarra, and the Catalan Institute of Oncology (ICO; Spain); Swedish Cancer Society, Swedish Research Council and County Councils of Skåne and Västerbotten (Sweden); and Cancer Research UK (14136 to EPIC–Norfolk; C8221/A29017 to EPIC–Oxford) and Medical Research Council (1000143 to EPIC–Norfolk; MR/M012190/1 to EPIC–Oxford; UK). Where authors are identified as personnel of the International Agency for Research on Cancer or WHO, they are responsible for the views expressed in this Article and they do not necessarily represent the decisions, policy, or views of the International Agency for Research on Cancer or WHO. Publisher Copyright: © 2023 World Health Organization UPDATE NOTICE Correction to Lancet Planet Health 2023; 7: e219–32. The Lancet Planetary Health. 2023;7(5):e357. Scopus ID: 85158098931 |
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2023 |
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