Occurrence and predictors factors for delirium in critically-ill older patients: a prospective cohort study
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Tipo de documento: | Dissertação |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://hdl.handle.net/10216/139746 |
Resumo: | Purpose This study aims to analyze the occurrence of delirium in critically-ill older patients and to identify predictor factors for delirium. Methods This prospective study included critically-ill older patients admitted into level II units of Intensive Care Medicine Department of a University Hospital. Patients with Glasgow Coma Scale score ≤11, traumatic brain injury, terminal disease, history of psychosis, blindness/deafness or inability to understanding/speaking Portuguese were excluded. The Confusion Assessment Method-Short form (CAM-4) was used to delirium assessment. Results The final sample (n=105) had a median age of 80 years, being the majority female (56.2%), widowed (49.5%) and with complete primary education (53%). Through CAM-4, 36.2% of the patients had delirium. The delirium group presented more pre-existing cognitive decline (48.6% vs 19.6%, p=0.04) and severe dependency in instrumental activities of daily living (34.3% vs 14.8%, p=0.032), comparing to patients without delirium. The final multiple logistic regression model explained that patients with previous cognitive decline presented a higher risk for delirium (OR: 4.663, 95% CI: 1.055-20.599, p=0.042). Conclusion These findings corroborate previous studies, showing that cognitive decline is an independent predictor for delirium in older patients. This study is an important contribution for the knowledge regarding the predictor factors for delirium. The recognition of these factors will help to identify patients who are at high risk for this syndrome, and to implement an early screening and prevention strategies. However, further studies with larger samples, recruited from other clinical settings as well as analyzing other potential factors for delirium, will be needed. |
id |
RCAP_e400742bb3e7376cb5801ba2a7cbdef4 |
---|---|
oai_identifier_str |
oai:repositorio-aberto.up.pt:10216/139746 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Occurrence and predictors factors for delirium in critically-ill older patients: a prospective cohort studyMedicina clínicaClinical medicinePurpose This study aims to analyze the occurrence of delirium in critically-ill older patients and to identify predictor factors for delirium. Methods This prospective study included critically-ill older patients admitted into level II units of Intensive Care Medicine Department of a University Hospital. Patients with Glasgow Coma Scale score ≤11, traumatic brain injury, terminal disease, history of psychosis, blindness/deafness or inability to understanding/speaking Portuguese were excluded. The Confusion Assessment Method-Short form (CAM-4) was used to delirium assessment. Results The final sample (n=105) had a median age of 80 years, being the majority female (56.2%), widowed (49.5%) and with complete primary education (53%). Through CAM-4, 36.2% of the patients had delirium. The delirium group presented more pre-existing cognitive decline (48.6% vs 19.6%, p=0.04) and severe dependency in instrumental activities of daily living (34.3% vs 14.8%, p=0.032), comparing to patients without delirium. The final multiple logistic regression model explained that patients with previous cognitive decline presented a higher risk for delirium (OR: 4.663, 95% CI: 1.055-20.599, p=0.042). Conclusion These findings corroborate previous studies, showing that cognitive decline is an independent predictor for delirium in older patients. This study is an important contribution for the knowledge regarding the predictor factors for delirium. The recognition of these factors will help to identify patients who are at high risk for this syndrome, and to implement an early screening and prevention strategies. However, further studies with larger samples, recruited from other clinical settings as well as analyzing other potential factors for delirium, will be needed.2021-06-232021-06-23T00:00:00Z2031-06-22T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttps://hdl.handle.net/10216/139746TID:203179099engRita Sofia Carneiro Martinsinfo:eu-repo/semantics/embargoedAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T16:12:44Zoai:repositorio-aberto.up.pt:10216/139746Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:39:06.162747Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Occurrence and predictors factors for delirium in critically-ill older patients: a prospective cohort study |
title |
Occurrence and predictors factors for delirium in critically-ill older patients: a prospective cohort study |
spellingShingle |
Occurrence and predictors factors for delirium in critically-ill older patients: a prospective cohort study Rita Sofia Carneiro Martins Medicina clínica Clinical medicine |
title_short |
Occurrence and predictors factors for delirium in critically-ill older patients: a prospective cohort study |
title_full |
Occurrence and predictors factors for delirium in critically-ill older patients: a prospective cohort study |
title_fullStr |
Occurrence and predictors factors for delirium in critically-ill older patients: a prospective cohort study |
title_full_unstemmed |
Occurrence and predictors factors for delirium in critically-ill older patients: a prospective cohort study |
title_sort |
Occurrence and predictors factors for delirium in critically-ill older patients: a prospective cohort study |
author |
Rita Sofia Carneiro Martins |
author_facet |
Rita Sofia Carneiro Martins |
author_role |
author |
dc.contributor.author.fl_str_mv |
Rita Sofia Carneiro Martins |
dc.subject.por.fl_str_mv |
Medicina clínica Clinical medicine |
topic |
Medicina clínica Clinical medicine |
description |
Purpose This study aims to analyze the occurrence of delirium in critically-ill older patients and to identify predictor factors for delirium. Methods This prospective study included critically-ill older patients admitted into level II units of Intensive Care Medicine Department of a University Hospital. Patients with Glasgow Coma Scale score ≤11, traumatic brain injury, terminal disease, history of psychosis, blindness/deafness or inability to understanding/speaking Portuguese were excluded. The Confusion Assessment Method-Short form (CAM-4) was used to delirium assessment. Results The final sample (n=105) had a median age of 80 years, being the majority female (56.2%), widowed (49.5%) and with complete primary education (53%). Through CAM-4, 36.2% of the patients had delirium. The delirium group presented more pre-existing cognitive decline (48.6% vs 19.6%, p=0.04) and severe dependency in instrumental activities of daily living (34.3% vs 14.8%, p=0.032), comparing to patients without delirium. The final multiple logistic regression model explained that patients with previous cognitive decline presented a higher risk for delirium (OR: 4.663, 95% CI: 1.055-20.599, p=0.042). Conclusion These findings corroborate previous studies, showing that cognitive decline is an independent predictor for delirium in older patients. This study is an important contribution for the knowledge regarding the predictor factors for delirium. The recognition of these factors will help to identify patients who are at high risk for this syndrome, and to implement an early screening and prevention strategies. However, further studies with larger samples, recruited from other clinical settings as well as analyzing other potential factors for delirium, will be needed. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-06-23 2021-06-23T00:00:00Z 2031-06-22T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/masterThesis |
format |
masterThesis |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://hdl.handle.net/10216/139746 TID:203179099 |
url |
https://hdl.handle.net/10216/139746 |
identifier_str_mv |
TID:203179099 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/embargoedAccess |
eu_rights_str_mv |
embargoedAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799136297680371712 |