New pricing models for generic medicines to ensure long-term sustainable competition in Europe

Detalhes bibliográficos
Autor(a) principal: Francois, Clement
Data de Publicação: 2023
Outros Autores: Gawlik, Gabriela, Mestre-Ferrandiz, Jorge, Pana, Adrian, Perelman, Julian, Yfantopoulos, John, Simoens, Steven
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/159723
Resumo: Funding Information: This study was funded by Medicines for Europe. Funding Information: CF and GG worked for Creativ-Ceutical (Which has been taken over by Putnam PHMR) which received funding from Medicines for Europe to undertake the study. SS has previously held the EGA Chair “European policy towards generic medicines”. Publisher Copyright: Copyright © 2023 Francois, Gawlik, Mestre-Ferrandiz, Pana, Perelman, Yfantopoulos and Simoens.
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spelling New pricing models for generic medicines to ensure long-term sustainable competition in EuropecompetitionEuropegeneric medicinespricingsustainabilityPharmacologyPharmacology (medical)Funding Information: This study was funded by Medicines for Europe. Funding Information: CF and GG worked for Creativ-Ceutical (Which has been taken over by Putnam PHMR) which received funding from Medicines for Europe to undertake the study. SS has previously held the EGA Chair “European policy towards generic medicines”. Publisher Copyright: Copyright © 2023 Francois, Gawlik, Mestre-Ferrandiz, Pana, Perelman, Yfantopoulos and Simoens.Background: Price erosion of generic medicines over time as a result of existing pricing policies in combination with increasing operational costs of these products due to high inflation, undermine long-term sustainable competition in European off-patent medicines markets. Therefore, the aim of this study is to identify new potential pricing models for retail generic medicines in Europe, examine their pros and cons, and illustrate them with examples inside or outside the pharmaceutical sector. Methods: A targeted literature review, one-to-one interviews and a joint advisory board meeting with experts from five European countries were carried out to assess potential pricing models for generic medicines. Results: We identified ten pricing models that can be applied to generic medicines. The tiered pricing model is viewed as a sustainable solution ensuring competitiveness, but requires market monitoring using a supportive IT infrastructure. De-linking the price of generic medicines from that of the off-patent originator medicine prevents the originator from forcing generic medicines’ prices to unsustainable levels. Higher costs due to inflation can be compensated in the automatic indexation model. Other pricing models that have less implementation potential include the one-in-one/multiple-out model, tax credits, value-based pricing, volume for savings and guaranteed margin/fee models. The hypothecated tax and cost allocation models, which add a patient fee to generic medicines prices, are not likely to be socially acceptable. Conclusion: When considering a new pricing model for generic medicines, the impact on innovative medicines and the characteristics of the healthcare system in a given country need to be taken into account. Also, there is a need to continuously follow up the level of competition in off-patent medicines markets and to identify sustainability risks.Escola Nacional de Saúde Pública (ENSP)Comprehensive Health Research Centre (CHRC) - Pólo ENSPCentro de Investigação em Saúde Pública (CISP/PHRC)RUNFrancois, ClementGawlik, GabrielaMestre-Ferrandiz, JorgePana, AdrianPerelman, JulianYfantopoulos, JohnSimoens, Steven2023-11-08T22:09:26Z20232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/159723eng1663-9812PURE: 75688853https://doi.org/10.3389/fphar.2023.1200641info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:42:11Zoai:run.unl.pt:10362/159723Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:57:40.608923Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv New pricing models for generic medicines to ensure long-term sustainable competition in Europe
title New pricing models for generic medicines to ensure long-term sustainable competition in Europe
spellingShingle New pricing models for generic medicines to ensure long-term sustainable competition in Europe
Francois, Clement
competition
Europe
generic medicines
pricing
sustainability
Pharmacology
Pharmacology (medical)
title_short New pricing models for generic medicines to ensure long-term sustainable competition in Europe
title_full New pricing models for generic medicines to ensure long-term sustainable competition in Europe
title_fullStr New pricing models for generic medicines to ensure long-term sustainable competition in Europe
title_full_unstemmed New pricing models for generic medicines to ensure long-term sustainable competition in Europe
title_sort New pricing models for generic medicines to ensure long-term sustainable competition in Europe
author Francois, Clement
author_facet Francois, Clement
Gawlik, Gabriela
Mestre-Ferrandiz, Jorge
Pana, Adrian
Perelman, Julian
Yfantopoulos, John
Simoens, Steven
author_role author
author2 Gawlik, Gabriela
Mestre-Ferrandiz, Jorge
Pana, Adrian
Perelman, Julian
Yfantopoulos, John
Simoens, Steven
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Escola Nacional de Saúde Pública (ENSP)
Comprehensive Health Research Centre (CHRC) - Pólo ENSP
Centro de Investigação em Saúde Pública (CISP/PHRC)
RUN
dc.contributor.author.fl_str_mv Francois, Clement
Gawlik, Gabriela
Mestre-Ferrandiz, Jorge
Pana, Adrian
Perelman, Julian
Yfantopoulos, John
Simoens, Steven
dc.subject.por.fl_str_mv competition
Europe
generic medicines
pricing
sustainability
Pharmacology
Pharmacology (medical)
topic competition
Europe
generic medicines
pricing
sustainability
Pharmacology
Pharmacology (medical)
description Funding Information: This study was funded by Medicines for Europe. Funding Information: CF and GG worked for Creativ-Ceutical (Which has been taken over by Putnam PHMR) which received funding from Medicines for Europe to undertake the study. SS has previously held the EGA Chair “European policy towards generic medicines”. Publisher Copyright: Copyright © 2023 Francois, Gawlik, Mestre-Ferrandiz, Pana, Perelman, Yfantopoulos and Simoens.
publishDate 2023
dc.date.none.fl_str_mv 2023-11-08T22:09:26Z
2023
2023-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/159723
url http://hdl.handle.net/10362/159723
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1663-9812
PURE: 75688853
https://doi.org/10.3389/fphar.2023.1200641
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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